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科研机构
上海药物研究所 [9]
江苏大学 [1]
大连化学物理研究所 [1]
湖南大学 [1]
兰州化学物理研究所 [1]
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期刊论文 [13]
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2018 [1]
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1998 [1]
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分析化学与药物化学 [1]
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Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2 ',3 ': 4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5 '-monophosphate-activated protein kinase (AMPK)
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 2017-2027
作者:
Gu, Zhanni
;
Wu, Lingyan
;
Duan, Yanan
;
Wang, Jiang
;
Zhou, Shengbin
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
Adenosine 5 '-monophosphate-activated protein kinase
AMPK activators
Berberine
Tetrahydroberberine
T2DM
Design, synthesis and. biological evaluation of 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines as novel adenosine 5 '-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of type 2 diabetes
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 448-464
作者:
Zhou, Shengbin
;
Duan, Yanan
;
Wang, Jiang
;
Zhang, Jin
;
Sun, Haifeng
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
Tetrahydroberberine
4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines
Mitochondrial respiration
AMPK indirect activators
db/db mice
Effects of tetrahydroberberine and tetrahydropalmatine on hepatic cytochrome P450 expression and their toxicity in mice
期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2017, 卷号: 268, 页码: 47-52
作者:
Wang, Dujun[1]
;
Wang, Kai[2]
;
Sui, Danjuan[3]
;
Ouyang, Zhen[4]
;
Xu, Haiyu[5]
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/24
Tetrahydroberberine
Tetrahydropalmatine
Cytochrome P450
Expression level
Toxicity
Cloning and Expression Analysis of Tetrahydroberberine Oxidase (STOX) Gene in Macleaya cordata
期刊论文
Genomics and Applied Biology, 2017, 卷号: Vol.36 No.6, 页码: 2458-2463
作者:
Huang Peng
;
Liu Jinfeng
;
Qing Zhixing
;
Liu Yisong
;
Tang Qi
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  |  
浏览/下载:6/0
  |  
提交时间:2019/12/31
Macleaya cordata
Tetrahydroberberine oxidase
Real-time quantitative expression
Tetrahydroberberine blocks ATP-sensitive potassium channels in dopamine neurons acutely-dissociated from rat substantia nigra pars compacta
期刊论文
NEUROPHARMACOLOGY, 2010, 卷号: 59, 期号: 7-8, 页码: 567-572
作者:
Wu, Chen
;
Yang, Kechun
;
Liu, Qiang
;
Wakui, Matoko
;
Jin, Guo-Zhang
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Tetrahydroberberine
Dopaminergic neurons
Substantia nigra compacta
ATP-sensitive K+ channel
Rotenone
Parch-clamp
NMR Characterization and Structural Elucidation of Fluorine Derivative of Tetrahydroberberine
期刊论文
Chinese Journal of Magnetic Resonance, 2009, 卷号: 26, 期号: 1, 页码: 111-119
作者:
ZHANG Pei-xuan
;
LI Jian-feng
;
WEI Ya-bing
;
SHEN Jing-shan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
nuclear magnetic resonance
structure elucidation
mass spectrometry
fluoro tetrahydroberberine
Chiral high-performance liquid chromatographic separation of the enantiomers of tetrahydropalmatine and tetrahydroberberine, isolated from Corydalis yanhusuo
期刊论文
Anal Bioanal Chem, 2006, 卷号: 384, 页码: 939-945
作者:
Shi YP(师彦平)
;
Shi YP(师彦平)
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2012/10/14
Enantiomer separation
Polysaccharide carbamate phase
Specific rotation
Circular dichroism
Tetrahydropalmatine
Tetrahydroberberine
Investigation of the metabolism of 7-(4-chlorbenzyl)7,8,13,13a-tetrahydroberberine chloride in the rat
期刊论文
european journal of drug metabolism and pharmacokinetics, 1998, 卷号: 23, 期号: 1, 页码: 41-44
作者:
Feng, N
;
Zhang, Z
;
An, D
;
Huang, W
;
Wang, G
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2015/11/09
metabolism
7-(4-chlorbenzyl)-7
rat
LC/MS
LC/NMR
8
13
13a-tetrahydroberberine chloride
Tetrahydroberberine blocks membrane K+ channels underlying its inhibition of intracellular message-mediated outward currents in acutely dissociated CA1 neurons from rat hippocampus
期刊论文
BRAIN RESEARCH, 1997, 卷号: 775, 期号: 1-2, 页码: 214-218
作者:
Wu, J
;
Jin, GZ
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  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
tetrahydroberberine
K+ current
K+ channel
hippocampus
dissociated neuron
patch clamp
Tetrahydroberberine inhibits acetylcholine-induced K+ current in acutely dissociated rat hippocampal CA1 pyramidal neurons
期刊论文
NEUROSCIENCE LETTERS, 1997, 卷号: 222, 期号: 2, 页码: 115-118
作者:
Wu, J
;
Jin, GZ
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
tetrahydroberberine
acetylcholine
K+ current
rat hippocampus
dissociated neurons
patch-clamp
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