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Metabolism, pharmacokinetics, and hepatic disposition of xanthones and saponins on Zhimu treatments for exploratively interpreting the discrepancy between the herbal safety and timosaponin A3-induced hepatotoxicity 期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1923-1934
作者:  Xie, Yang;  Zhou, Xu;  Pei, Hu;  Chen, Ming-Cang;  Sun, Zhao-Lin
收藏  |  浏览/下载:96/0  |  提交时间:2019/01/08
Absorption, Metabolism, and Pharmacokinetics Profiles of Norathyriol, an Aglycone of Mangiferin, in Rats by HPLC-MS/MS 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018, 卷号: 66, 期号: 46, 页码: 12227-12235
作者:  Guo, Xiaozhen;  Cheng, Mingcang;  Hu, Pei;  Shi, Zhangpeng;  Chen, Shuoji
收藏  |  浏览/下载:269/0  |  提交时间:2019/01/08
metabolismpharmacokineticsandhepaticdispositionofxanthonesandsaponinsonzhimutreatmentsforexplorativelyinterpretingthediscrepancybetweentheherbalsafetyandtimosaponina3inducedhepatotoxicity 期刊论文
actapharmacologicasinica, 2018, 卷号: 39, 期号: 12, 页码: 1923
作者:  Xie Yang;  Zhou Xu;  Pei Hu;  Chen Mingcang;  Sun Zhaolin
收藏  |  浏览/下载:5/0  |  提交时间:2020/07/01
Pharmacokinetics of mangiferin and its metabolite-Norathyriol, Part 1: Systemic evaluation of hepatic first-pass effect in vitro and in vivo 期刊论文
BIOFACTORS, 2016, 卷号: 42, 期号: 5, 页码: 533-544
作者:  Tian, Xiaoting;  Gao, Yu;  Xu, Zhou;  Lian, Shan;  Ma, Yuanjie
收藏  |  浏览/下载:28/0  |  提交时间:2019/01/08
Pharmacokinetics of mangiferin and its metabolite-Norathyriol, Part 2: Influence of UGT, CYP450, P-gp, and enterobacteria and the potential interaction in Rhizoma Anemarrhenae decoction with timosaponin B2 as the major contributor 期刊论文
BIOFACTORS, 2016, 卷号: 42, 期号: 5, 页码: 545-555
作者:  Tian, Xiaoting;  Xu, Zhou;  Li, Zhixiong;  Ma, Yuanjie;  Lian, Shan
收藏  |  浏览/下载:27/0  |  提交时间:2019/01/08
Mangiferin attenuates the symptoms of dextran sulfate sodium-induced colitis in mice via NF-κB and MAPK signaling inactivation 期刊论文
International immunopharmacology, 2014, 卷号: 23, 期号: 1, 页码: 170-8
作者:  Dou, Wei;  Zhang, Jingjing;  Ren, Gaiyan;  Ding, Lili;  Sun, Aning
收藏  |  浏览/下载:20/0  |  提交时间:2019/01/08
Timosaponin A3 induces hepatotoxicity in rats through inducing oxidative stress and down-regulating bile acid transporters 期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 9, 页码: 1188-1198
作者:  Wu, Zhi-tao;  Qi, Xin-ming;  Sheng, Jing-jing;  Ma, Lei-lei;  Ni, Xuan
收藏  |  浏览/下载:20/0  |  提交时间:2019/01/08
Xanthones from Swertia mussotii as Multitarget-Directed Antidiabetic Agents 期刊论文
CHEMMEDCHEM, 2014, 卷号: 9, 期号: 7, 页码: 1374-1377
作者:  Zheng, Huan-Huan;  Luo, Cui-Ting;  Chen, Heru;  Lin, Juan-Na;  Ye, Chun-Ling
收藏  |  浏览/下载:12/0  |  提交时间:2019/01/08
Antioxidant xanthones from Swertia mussotii, a high altitude plant 期刊论文
FITOTERAPIA, 2013, 卷号: 91, 页码: 140-147
作者:  Luo, Cui-Ting;  Mao, Shuang-Shuang;  Liu, Fang-Lan;  Yang, Mao-xun;  Chen, Heru
收藏  |  浏览/下载:65/0  |  提交时间:2019/01/08
Characterization and Identification of Major Constituents in Baihe Zhimu Decoction by HPLC-MSn 期刊论文
ASIAN JOURNAL OF CHEMISTRY, 2013, 卷号: 25, 期号: 16, 页码: 8976-8980
作者:  Jiang, Weixin;  Liu, Zhiyu;  Wu, Bin;  Huang, Chenggang
收藏  |  浏览/下载:18/0  |  提交时间:2019/01/08


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