Antioxidant xanthones from Swertia mussotii, a high altitude plant

doi:10.1016/j.fitote.2013.08.021

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	Antioxidant xanthones from Swertia mussotii, a high altitude plant
	Luo, Cui-Ting 2; Mao, Shuang-Shuang 2; Liu, Fang-Lan 2; Yang, Mao-xun 2; Chen, Heru 2,3,4; Kurihara, Hiroshi 2,4; Li, Yulin 1
刊名	FITOTERAPIA
	2013-12
卷号	91 页码:140-147
关键词	Swertia L. Swertia mussotii Xanthones Antioxidant ORAC
ISSN号	0367-326X
DOI	10.1016/j.fitote.2013.08.021
文献子类	Article
英文摘要	Four new xanthones, 3,5,6,8-tetrahydroxyxanthone-1-C-beta-D-glucoside (1), 7-hydroxy-3,4,8-trimethoxyxanthone-1-O-(beta-D-glucoside) (2), 6-hydroxy-3,5-dimethoxyxanthone-1-O-(beta-D-glucoside) (3), 3,4,7,8-tetramethoxyxanthone-1-O-(beta-D-glucoside) (4), together with twenty-one known xanthones (5-25) were isolated from the ethanol aqueous extract of Swertia mussotii. Their structures were elucidated via spectroscopic analyses. Oxygen radical absorbance capacity of all the isolated xanthones was systematically evaluated by ORAC(FL) assay. Results disclose that all the tested xanthones display moderate to excellent antioxidant activity, where I is the most active compound and 13 is the least one. A preliminary structure-activity relationship is also discussed. (C) 2013 Elsevier B.V. All rights reserved.
资助项目	National Natural Science Foundation of China[81172982] ; Guangdong Provincial Project of Science and Technology[2010A030100006] ; State Key Laboratory of Drug Research[SIMM1302KF-12]
WOS关键词	GARCINIA-MANGOSTANA ; MEDICINE ; FRANCH ; CONSTITUENTS ; GENTIANACEAE ; METABOLITES ; MANGIFERIN ; CELLS
WOS研究方向	Pharmacology & Pharmacy
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000327574300020
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/277355]
专题	新药研究国家重点实验室中科院受体结构与功能重点实验室
通讯作者	Chen, Heru
作者单位	1.Chinese Acad Sci, Northwest Inst Plateau Biol, Xining 810001, Peoples R China 2.Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Guangzhou 510632, Guangdong, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 4.Guangdong Prov Key Lab Pharmacodynam Constituents, Guangzhou 510632, Guangdong, Peoples R China;
推荐引用方式 GB/T 7714	Luo, Cui-Ting,Mao, Shuang-Shuang,Liu, Fang-Lan,et al. Antioxidant xanthones from Swertia mussotii, a high altitude plant[J]. FITOTERAPIA,2013,91:140-147.
APA	Luo, Cui-Ting.,Mao, Shuang-Shuang.,Liu, Fang-Lan.,Yang, Mao-xun.,Chen, Heru.,...&Li, Yulin.(2013).Antioxidant xanthones from Swertia mussotii, a high altitude plant.FITOTERAPIA,91,140-147.
MLA	Luo, Cui-Ting,et al."Antioxidant xanthones from Swertia mussotii, a high altitude plant".FITOTERAPIA 91(2013):140-147.