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科研机构
上海药物研究所 [10]
内容类型
期刊论文 [10]
发表日期
2021 [2]
2020 [4]
2018 [1]
2016 [2]
2015 [1]
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Clerodane diterpenoids from Dodonaea viscosa and their inhibitory effects on ATP citrate lyase
期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 183, 页码: 8
作者:
Lei, Chun
;
Wang, Xiao-Hang
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/06/11
Dodonaea viscosa (L.) Jacq
Sapindaceae
Clerodane diterpenoids
Dodovisins A-F
ATP citrate Lyase
Clerodane diterpenoids from Dodonaea viscosa and their inhibitory effects on ATP citrate lyase
期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 183, 页码: 8
作者:
Lei, Chun
;
Wang, Xiao-Hang
;
Liu, Yi-Nan
;
Zhao, Ting
;
Hu, Zhu
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/06/11
Dodonaea viscosa (L.) Jacq
Sapindaceae
Clerodane diterpenoids
Dodovisins A-F
ATP citrate Lyase
Revelation of AbfR in regulation of mismatch repair and energy metabolism in S. epidermidis by integrated proteomic and metabolomic analysis
期刊论文
JOURNAL OF PROTEOMICS, 2020, 卷号: 226, 页码: 10
作者:
Gu, Lei
;
Liu, Xing
;
Wang, Yu-Qiu
;
Zhou, Yan-ting
;
Zhu, Hong-wen
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/21
Staphylococcus epidermidis
AbfR transcription factor
Oxidation-sensing regulator
Oxidative stress
TMT10-plex labelling
Antibiotic resistance regulator
Revelation of AbfR in regulation of mismatch repair and energy metabolism in S. epidermidis by integrated proteomic and metabolomic analysis
期刊论文
JOURNAL OF PROTEOMICS, 2020, 卷号: 226, 页码: 10
作者:
Gu, Lei
;
Liu, Xing
;
Wang, Yu-Qiu
;
Zhou, Yan-ting
;
Zhu, Hong-wen
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/21
Staphylococcus epidermidis
AbfR transcription factor
Oxidation-sensing regulator
Oxidative stress
TMT10-plex labelling
Antibiotic resistance regulator
Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Tian, Qian-qian
;
Zhu, Yun-ting
;
Diao, Xing-xing
;
Zhang, Xiang-lei
;
Xu, Ye-chun
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2020/12/24
PDE5 inhibitor
TPN729
M3
species difference
pharmacokinetics
metabolite identification
Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 5
作者:
Satheeshkumar, Rajendran
;
Zhu, Rui
;
Feng, Bo
;
Huang, Chao
;
Gao, Ya
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Heterocyclic bis-aryl amides
PTP1B
SHP2
Inhibitors
Structure-activity relationships (SAR)
Transgelin-2 as a therapeutic target for asthmatic pulmonary resistance
期刊论文
SCIENCE TRANSLATIONAL MEDICINE, 2018, 卷号: 10, 期号: 427
作者:
Yin, Lei-Miao
;
Xu, Yu-Dong
;
Peng, Ling-Ling
;
Duan, Ting-Ting
;
Liu, Jia-Yuan
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
Lineage-Specific Reductions of Plastid Genomes in an Orchid Tribe with Partially and Fully Mycoheterotrophic Species
期刊论文
Genome biology and evolution, 2016, 卷号: 8, 期号: 7, 页码: 2164-75
作者:
Feng, Yan-Lei
;
Wicke, Susann
;
Li, Jian-Wu
;
Han, Yu
;
Lin, Choun-Sea
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation
期刊论文
NATURE COMMUNICATIONS, 2016, 卷号: 7
作者:
Li, Defang
;
Liu, Jin
;
Guo, Baosheng
;
Liang, Chao
;
Dang, Lei
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Application of chemical biology in target identification and drug discovery
期刊论文
ARCHIVES OF PHARMACAL RESEARCH, 2015, 卷号: 38, 期号: 9, 页码: 1642-1650
作者:
Zhu, Yue
;
Xiao, Ting
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Chemical biology
Genomics
Proteomics
Drug discovery
Target validation
High-throughput screening (HTS)
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