Clerodane diterpenoids from Dodonaea viscosa and their inhibitory effects on ATP citrate lyase

doi:10.1016/j.phytochem.2020.112614

	Clerodane diterpenoids from Dodonaea viscosa and their inhibitory effects on ATP citrate lyase
	Lei, Chun 1; Wang, Xiao-Hang 1; Liu, Yi-Nan 2; Zhao, Ting 1; Hu, Zhu 1; Li, Jing-Ya 2,3; Hou, Ai-Jun 1
刊名	PHYTOCHEMISTRY
	2021-03-01
卷号	183 页码:8
关键词	Dodonaea viscosa (L.) Jacq Sapindaceae Clerodane diterpenoids Dodovisins A-F ATP citrate Lyase
ISSN号	0031-9422
DOI	10.1016/j.phytochem.2020.112614
通讯作者	Hou, Ai-Jun(ajhou@shmu.edu.cn)
英文摘要	Six undescribed clemdane diterpenoids, dodovisins A-F, together with nine known ones, were isolated from the aerial parts of Dodonaea viscosa (L.) Jacq. Their structures were elucidated by extensive spectroscopic techniques, X-ray crystallographic analysis, and ECD calculation. Dodovisins A and B possess a rare carbon skeleton featuring a bicyclo[6.2.0]decane motif. Dodovisins C-E represent the first clerodane diterpenoids with a 4(5 -> 19)-abeo2,4,10(1)-triene moiety. Dodovisins A, E, and strictic acid showed potent inhibitory activities against ATP citrate lyase.
资助项目	National Natural Science Foundation of China[21672040] ; National Natural Science Foundation of China[82073717] ; Drug Innovation Major Project of China[2018ZX09735001-002-006] ; Fudan-SIMM Joint Research Fund[FU-SIMM20181011]
WOS关键词	STRICTIC ACID ; CONSTITUENTS ; DERIVATIVES
WOS研究方向	Biochemistry & Molecular Biology ; Plant Sciences
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000631272700006
内容类型	期刊论文
源URL	[http://119.78.100.183/handle/2S10ELR8/296533]
专题	中国科学院上海药物研究所
通讯作者	Hou, Ai-Jun
作者单位	1.Fudan Univ, Sch Pharm, State Key Lab Med Neurobiol, Shanghai 201203, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China 3.Univ Chinese Acad Sci, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Lei, Chun,Wang, Xiao-Hang,Liu, Yi-Nan,et al. Clerodane diterpenoids from Dodonaea viscosa and their inhibitory effects on ATP citrate lyase[J]. PHYTOCHEMISTRY,2021,183:8.
APA	Lei, Chun.,Wang, Xiao-Hang.,Liu, Yi-Nan.,Zhao, Ting.,Hu, Zhu.,...&Hou, Ai-Jun.(2021).Clerodane diterpenoids from Dodonaea viscosa and their inhibitory effects on ATP citrate lyase.PHYTOCHEMISTRY,183,8.
MLA	Lei, Chun,et al."Clerodane diterpenoids from Dodonaea viscosa and their inhibitory effects on ATP citrate lyase".PHYTOCHEMISTRY 183(2021):8.