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科研机构
上海药物研究所 [132]
内容类型
期刊论文 [130]
会议论文 [1]
学位论文 [1]
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2021 [13]
2020 [12]
2019 [12]
2018 [7]
2017 [9]
2016 [16]
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Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Rosmarinic Acid Suppresses Abdominal Aortic Aneurysm Progression in Apolipoprotein E-deficient Mice
期刊论文
PLANTA MEDICA, 2021, 页码: 14
作者:
Bian, Huimiao
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/12/16
abdominal aortic aneurysm
rosmarinic acid
salvianolic acid C
salvianolic acid B
Salvia miltiorrhiza Bunge
Labiatae
Molecular simulation studies of the interactions between the human/ pangolin/cat/bat ACE2 and the receptor binding domain of the SARS-CoV-2 spike protein
期刊论文
BIOCHIMIE, 2021, 卷号: 187, 页码: 1-13
作者:
Ma, Shaojie
;
Li, Hui
;
Yang, Jun
;
Yu, Kunqian
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2021/08/17
SARS-CoV-2
ACE2
Molecular simulation
Binding energy
Animal hosts
Discovery of SARS-CoV-2-E channel inhibitors as antiviral candidates
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 7
作者:
Wang, Yi
;
Fang, Sui
;
Wu, Yan
;
Cheng, Xi
;
Zhang, Lei-ke
收藏
  |  
浏览/下载:110/0
  |  
提交时间:2021/08/17
SARS-CoV-2
envelope protein (2-E)
cation channel
high-throughput screening (HTS)
anti-virus
Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 7, 页码: 1885-1902
作者:
Wu, Xu
;
Yin, Chun
;
Ma, Jiang
;
Chai, Stella
;
Zhang, Chunyuan
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  |  
浏览/下载:40/0
  |  
提交时间:2021/11/04
Multidrug resistance
ABCB1
Polyoxypregnane
Combination chemotherapy
Marsdenia tenacissima
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
Glycogen synthase kinase 3 beta inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 2, 页码: 18
作者:
Zhang, Ning
;
Tian, Yu-Nan
;
Zhou, Li-Na
;
Li, Meng-Zhu
;
Chen, Hua-Dong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
Nosiheptide analogues as potential antibacterial agents via dehydroalanine region modifications: Semi-synthesis, antimicrobial activity and molecular docking study
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 31, 页码: 10
作者:
Fan, Yafei
;
Chen, Hangfei
;
Mu, Ning
;
Wang, Wengui
;
Zhu, Kongkai
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
Nosiheptide analogues
Semi-synthesis
Antimicrobial activity
Molecular docking
Anti-nociceptive, anti-inflammatory and anti-arthritic activities of pregnane glycosides from the root bark of Periploca sepium Bunge
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 265, 页码: 12
作者:
Lin, Ze-min
;
Liu, Yu-ting
;
Huang, Yue-teng
;
Yang, Xiao-qian
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/05/24
Periploca sepium Bunge
Pregnane glycosides
Anti-nociceptive activity
Anti-inflammatory activity
Anti-arthritic activity
Inflammatory arthritis
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