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A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TPN171H, a Novel Phosphodiesterase Type 5 Inhibitor, in Healthy Subjects
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 卷号: 15, 页码: 2947-2959
作者:
Qian, Hongjie
;
Chen, Qian
;
Lang, Liyu
;
Zou, Yang
;
Pu, Huahua
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/08/17
TPN171H
PDE5 inhibitor
safety
pharmacokinetics
food effect
healthy subjects
Parallel group ICA plus ICA: Joint estimation of linked functional network variability and structural covariation with application to schizophrenia
期刊论文
HUMAN BRAIN MAPPING, 2019, 卷号: 40, 期号: 13, 页码: 3795-3809
作者:
Qi, Shile
;
Sui, Jing
;
Chen, Jiayu
;
Liu, Jingyu
;
Jiang, Rongtao
收藏
  |  
浏览/下载:106/0
  |  
提交时间:2019/12/16
group independent component analysis
multimodal fusion
parallel independent component analysis
schizophrenia
subjects' variability
temporal information
Interethnic scaling of fraction unbound of a drug in plasma and volume of distribution: an analysis of extrapolation from Caucasians to Chinese
期刊论文
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2019, 卷号: 75, 期号: 4
作者:
Yu, Guo
;
Zhou, Hong-Hao
;
Zheng, Qing-Shan
;
Li, Guo-Fu
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/05
Interethnic scaling
Fraction unbound
Volume of distribution
Healthy subjects
Clinical pharmacokinetics
Effects of a High-fat Meal on the Pharmacokinetics of the VEGFR Inhibitor Fruquintinib: A Randomized Phase I Study in Healthy Subjects
期刊论文
CLINICAL THERAPEUTICS, 2019, 卷号: 41, 期号: 8
作者:
Liu, Yun
;
Li, Tingting
;
Wang, Wei
;
Jia, Jingying
;
Liu, Yanmei
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/05
food effect
fruquintinib
healthy Chinese subjects
pharmacokinetics
Phase I
tolerability
Interethnic scaling of fraction unbound of a drug in plasma and volume of distribution: an analysis of extrapolation from Caucasians to Chinese
期刊论文
European journal of clinical pharmacology, 2019, 卷号: 75, 页码: 543-551
作者:
Yu Guo[1]
;
Zhou Hong-Hao[2]
;
Zheng Qing-Shan[3]
;
Li Guo-Fu[4]
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/04/22
Clinical pharmacokinetics
Fraction unbound
Healthy subjects
Interethnic scaling
Volume of distribution
Bradycardia and Tachycardia Detection Using a Synthesis-by-Analysis Modeling Approach of Pulsatile Signal
期刊论文
IEEE Access, 2019, 卷号: 7, 页码: 131256-131269
作者:
Chou, Yongxin
;
Gu, Jason
;
Liu, Jicheng
;
Gu, Ya
;
Lin, Jiajun
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/11/14
Cardiovascular system
Decision trees
Random forests
Analysis models
Classification performance
Classification results
Feature vectors
Healthy subjects
Kappa coefficient
Model-based method
Probabilistic neural networks
Short-term Safety, Tolerability, and Pharmacokinetics of MRX-I, an Oxazolidinone Antibacterial Agent, in Healthy Chinese Subjects
期刊论文
CLINICAL THERAPEUTICS, 2018, 卷号: 40, 期号: 2
作者:
Wu, Xiaojie
;
Li, Yunfei
;
Zhang, Jing
;
Zhang, Yingyuan
;
Yu, Jicheng
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  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
healthy subjects
MRX-I
pharmacokinetics
safety
A Tendon-driven Upper-limb Rehabilitation Robot
会议论文
作者:
Li, Min
;
Guo, Wenliang
;
Xu, Guanghua
;
Jia, Yanjun
;
Xie, Jun
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/11/19
Human subjects
Joint movement
Joint rotations
Physiological structures
Rehabilitation robot
Rehabilitation training
Secondary damage
Upper-limb rehabilitation
Metabolism of Piperaquine to Its Antiplasmodial Metabolites and Their Pharmacokinetic Profiles in Healthy Volunteers
期刊论文
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2018, 卷号: 62, 期号: 8
作者:
Liu, Huixiang
;
Zhou, Hongchang
;
Cai, Tianyu
;
Yang, Aijuan
;
Zang, Meitong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
piperaquine
metabolite
antiplasmodial activity
healthy subjects
pharmacokinetics
ANNOTATIONS.
期刊论文
Ethics & Human Research, 2018, 卷号: Vol.40 No.2, 页码: 19-20
-
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浏览/下载:3/0
  |  
提交时间:2019/12/24
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