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四川大学 [6]
上海药物研究所 [4]
中南大学 [3]
南华大学 [2]
厦门大学 [2]
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期刊论文 [31]
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Interactome Mapping Uncovers a General Role for Numb in Protein Kinase Regulation.
期刊论文
Molecular & cellular proteomics : MCP, 2018, 卷号: 17, 页码: 2216-2228
作者:
Wei Ran
;
Kaneko Tomonori
;
Liu Xuguang
;
Liu Huadong
;
Li Lei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/26
Protein kinases
Protein-Protein Interactions
Peptide array
Tyrosine Kinases
Numb
PTB domain
SMALI
Protein array
Efficacy and safety of rituximab in the treatment of refractory myasthenia gravis: Meta-analysis
期刊论文
Chinese Journal of Contemporary Neurology and Neurosurgery, 2018, 卷号: Vol.18 No.7, 页码: 494-500
作者:
Shan-shan CHU
;
Deng CHEN
;
Li-na ZHU
;
Ge TAN
;
Da XU
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/02/25
Myasthenia
gravis
Receptors,
cholinergic
Receptor
protein
⁃
tyrosine
kinases
Meta⁃analysis
Efficacy and safety of rituximab in the treatment of refractory myasthenia gravis: Meta-analysis
期刊论文
Chinese Journal of Contemporary Neurology and Neurosurgery, 2018, 卷号: Vol.18 No.7, 页码: 494-500
作者:
Shan-shan CHU
;
Deng CHEN
;
Li-na ZHU
;
Ge TAN
;
Da XU
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/02/25
Myasthenia
gravis
Receptors,
cholinergic
Receptor
protein
⁃
tyrosine
kinases
Meta⁃analysis
Synthesis and Activity Evaluation of Novel 3,4-Dihydro-benzo[b]-oxazepin-5(2H)-one Derivatives as Protein Kinases Inhibitors
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2017, 卷号: 37, 期号: 6, 页码: 1463-1472
作者:
Hou Guige
;
Jiang Chengshi
;
Liu Hongchun
;
Tong Linjiang
;
Peng Xia
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
3,4-dihydro-benzo[b]oxazepin-5(2H)-one derivatives
synthesis
protein-tyrosine kinases inhibitors
ErbB1
ErbB2
Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance
期刊论文
European Journal of Medicinal Chemistry, 2017, 卷号: 135, 页码: 34-48
作者:
Zha, Gao-Feng
;
Qin, Hua-Li*
;
Youssif, Bahaa G. M.
;
Amjad, Muhammad Wahab
;
Raja, Maria Abdul Ghafoor
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/04
Epidermal growth factor receptor (EGFR)
BRAF
Focal adhesion kinase (FAK)
Tubulin polymerization
Cancer cell lines
MDR
multidrug resistance
EGFR
epidermal growth factor receptor
EMEA
European Medicines Evaluation Agency
FDA
US Food and Drug Administration
NSCLC
non-small cell lung
FAK
focal adhesion kinase
RTK
receptor tyrosine kinases
MAPK
mitogen-activated protein kinase
ABC
ATP-binding cassette
NF-kB
NF-kappaB
FERM
Four-point-one, ezrin, radixin, moesin
TMP
Ligustrazine or tetramethylpyrazine
Adr
Adriamycin
DRS
death receptors
TFN
tumor necrosis factor
PI
propidium iodide
TKIs
tyrosine kinase inhibitors
FAR
fluorescence activity ratio
HRMS
high resolution mass spectra
TLC
thin layer chromatography
UV
ultraviolet
DMEM
Dulbecco's modified Eagle's medium
DMSO
dimethyl sulfoxide
IBX
2-iodoxybenzoic acid
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:
Yang, Xin
;
Xu, Zhipeng
;
Zhang, Chunlan
;
Cai, Zixin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/12/03
A1c
glycated hemoglobin
AACE
American Association of Clinical Endocrinologists
ACC
acetyl-CoA carboxylase
ADA
American Diabetes Association
Akt/PKB
tyrosine kinase/protein kinase B
AMP
adenosine monophosphate
AMPK
adenosine monophosphate-activated protein
Ang II
angiotensin II
ATP
adenosine triphosphate
BAT
brown adipose tissue
CHOP
CEBP-homologous protein
CEBP
CCAAT enhancer binding protein
CoA
coenzyme A
DPP
Diabetes Prevention Program
EASD
European Association for the Study of Diabetes
eNOS
endothelial nitric oxide synthase
ER
endoplasmic reticulum
FDA
Food and Drug Administration
FFA
free fatty acid
FOXO1
forkhead box protein O1
G6P
glucose 6-phosphate
GDM
gestational diabetes mellitus
GIPR
glucose-dependent insulinotropic polypeptide receptor
GLP-1R
glucagon-like peptide-1 receptor
GLUT1
glucose transporter-1
GLUT4
glucose transporter type 4
GLUTs
glucose transporters
G6P
glucose 6-phosphate, glucose transporter-1
GPR40
G protein-coupled receptor 40
HbA1c
hemoglobin A1c
HGP
hepatic glucose production
HSL
hormone sensitive lipase
IL-6
interleukin 6
INS-1
insulinoma cells in rat
IR
insulin resistance
IRS-1
insulin receptor substrate 1
JNK
c-Jun. N-terminal kinase
Kir6.2
inwardly rectifying potassium/kalium channel
LDs
lipid droplets
LDL
low density lipoprotein
LV
left ventricular
MIN6 cells
mouse insulinoma cells
MAPK
mitogen-activated protein kinases
mPTP
mitochondrial permeability transition pore opening
mTOR
mammalian target of rapamycin
NADPH
nicotinamide adenine dinucleotide phosphate
NF-kappaB
nuclear factors-kappa B
NIT-1 cells
insulinoma cells
p70S6K
p70 ribosomal S6 kinase
PA
palmitic acid
NOS
NADPH oxidase
p38 MAPK
p38 mitogen-activated protein kinase
PA
palmitic acid
PCOS
polycystic ovary syndrome
PGC-1α
peroxisome proliferator-activated receptor-g coactivator-1α
PI3K
phosphatidylinositol 3-kinase
PKB
protein kinase B
PKC
protein kinase C
PPARα
peroxisome-proliferator activated receptor α
PTP
permeability transition pore
RCT
randomized controlled trial
RISK
reperfusion injury salvage kinase
ROS
reactive oxygen species
SERCA2
reticulum sarcoplasmic Ca2 +-ATPase
RISK
reperfusion injury salvage kinase
Smad3
mothers against decapentaplegic homolog 3
SRC-2
steroid receptor coactivator 2
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TGFβ1
transforming growth factor β1
TLR4
Toll-like receptor
TNF-α
tumor necrosis factor α
TR4
testicular receptor 4
UKPDS
United Kingdom Prospective Diabetes Study
VLDL
very low density lipoprotein
Metformin
Pancreatic β Cells
Heart failure
Insulin sensitizer
Mfn2 protects dopaminergic neurons exposed to paraquat both in vitro and in vivo: Implications for idiopathic Parkinson's disease
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 6, 页码: 1359-1370
作者:
Zhao, Fanpeng
;
Wang, Wenzhang
;
Wang, Chunyu
;
Siedlak, Sandra L.
;
Fujioka, Hisashi
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
DA
dopaminergic
DIV
days in vitro
DLP1
dynamin-like protein 1
4-HNE
4-hydroxynonenal
JNKs
c-Jun N-terminal kinases
MPTP
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
MAP2
microtubule-associated protein-2
Fis1
mitochondrial fission 1
Mff
mitochondrial fission factor
Mfn2
mitofusin 2
MMP
mitochondrial membrane potential
Mfn1/2
mitofusin 1/2
OPA1
optic atrophy 1
PQ
paraquat
PD
Parkinson's disease
ROS
reactive oxygen species
SN
substantia nigra pars compacta
TMRM
tetramethylrhodamine methyl ester
TH
tyrosine hydroxylase
Tg
transgenic
Mitochondrial dynamics
DLP1
Drp1
Mfn2
Paraquat
Parkinson's disease
G-Protein G alpha(13) Functions with Abl Kinase to Regulate Actin Cytoskeletal Reorganization
期刊论文
JOURNAL OF MOLECULAR BIOLOGY, 2017, 卷号: 429, 期号: 24
作者:
Wang, Limin
;
Wang, Dawei
;
Xing, Bowen
;
Tan, Ying-cai
;
Huang, Jianyun
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
cell signaling
G-protein
Abl
tyrosine kinases
actin cytoskeleton
NOK/STYK1单克隆抗体的制备及应用
期刊论文
2016, 2016
张国芳
;
王银银
;
常智杰
;
ZHANG Guofang
;
WANG Yinyin
;
CHANG Zhijie
收藏
  |  
浏览/下载:9/0
Protein kinase-based neural signaling pathways for ginsenosides: a retrospective review
期刊论文
2015, 卷号: 35, 期号: 3, 页码: 349-354
作者:
He Wenbin
;
Zhang Junlong
;
Chen Naihong
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/13
Panax
Ginsenosides
Signal transduction
Protein kinase C
Calcium-calmodulin-dependent protein kinase type 2
JNK mitogen-activated protein kinases
Protein-tyrosine kinases
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