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科研机构
西安交通大学 [2]
上海药物研究所 [2]
中南大学 [1]
华南理工大学 [1]
湖南农业大学 [1]
内容类型
期刊论文 [6]
学位论文 [1]
发表日期
2018 [2]
2014 [2]
2013 [2]
2009 [1]
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HCBP6 upregulates human SREBP1c expression by binding to C/EBP beta-binding site in the SREBP1c promoter
期刊论文
BMB REPORTS, 2018, 卷号: 51, 页码: 33-38
作者:
Yang, Xueliang
;
Han, Ming
;
Liu, Shunai
;
Yuan, Xiaoxue
;
Liu, Xiaojing
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/11/19
HCBP6
SREBP1c
Triglyceride homeostasis
Transcription factor
C/EBP beta
HCBP6对肝细胞内甘油三酯合成的作用和机制研究
学位论文
2018
作者:
杨雪亮
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/26
甘油三酯
HCBP6
SREBP1c
启动子
磷酸化
Hypolipidemic Activity of Okra is Mediated Through Inhibition of Lipogenesis and Upregulation of Cholesterol Degradation
期刊论文
PHYTOTHERAPY RESEARCH, 2014, 卷号: 28, 页码: 268-273
作者:
Wang, Hong[1]
;
Chen, Gu[1]
;
Ren, Dandan[1]
;
Yang, Shang-Tian[1,2]
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/04/25
okra
hypolipidemic activity
CYP7A1
SREBP1c
FAS
polysaccharide
Mindin/Spondin 2 inhibits hepatic steatosis, insulin resistance, and obesity via interaction with peroxisome proliferator-activated receptor α in mice
期刊论文
Journal of Hepatology, 2014, 卷号: 60, 期号: 5, 页码: 1046-1054
作者:
Zhu, Li-Hua
;
Wang, Aibing
;
Luo, Pengcheng
;
Wang, Xinan
;
Jiang, Ding-Sheng
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/23
IR
insulin resistance
WT
wild type
KO
knockout
TG
transgenic
NTG
non-transgenic
NC
normal chow
HFD
high-fat diet
PPARα
peroxisome proliferator-activated receptor alpha
ECM
extracellular matrix
NL
normal liver
NAFLD
non-alcoholic fatty liver disease
H&E
hematoxylin and eosin
ALT
alanine transaminase
AST
aspartate transaminase
ALP
alkaline phosphatase
HMGCR
3-hydroxy-3-methyl-glutaryl-CoA reductase
LDL
low density lipoprotein
HDL
high density lipoprotein
LDLR
low-density lipoprotein receptor
GPAT
glycerol-3-phosphate acyltransferase
DGAT
diglyceride acyltransferase
FFA
free fatty acid
SREBP1c
sterol response element binding protein 1c
ACC
acetyl-CoA carboxylase
FAS
fatty acid synthase
SCD
stearoyl-CoA desaturase
LXR-α
liver X receptor-α
ARG-1
arginase-1
ABCA
ATP-binding cassette transporter A
ABCG
ATP-binding cassette transporter G
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
AMPK
AMP-activated protein kinase
IL
interleukin
TNF-α
tumor necrosis factor alpha
MCP-1
monocyte chemoattractant protein 1
MRC1
mannose receptor, C type 1
MGL
macrophage galactose-type C-type lectin
JNK
Jun N-terminal kinase
FBG
fasting glucose
HOMA-IR
homeostasis model assessment of insulin resistance
GTT
glucose tolerance test
ITT
intraperitoneal insulin tolerance test
Fins
fasting insulin
shRNA
short hairpin RNA
GFP
green fluorescent protein
IRS
insulin receptor substrate
Akt
protein kinase B
HSL
hormone sensitive lipase
ATGL
adipose triacylglycerol lipase
ACOX
acyl-coenzyme A oxidase
CPT-1α
carnitine palmitoyltransferase-1-α
LCAD
long-chain acyl-CoA dehydrogenase
MCAD
medium-chain acyl-CoA dehydrogenase
UCP
uncoupling protein
FGF21
fibroblast growth factor
PPRE
peroxisome proliferators response element
AUC
area under the curve
IKKβ
inhibitor of nuclear factor kappa B kinase beta subunit
Spondin 2
Fatty liver
Insulin resistance
PPARα
Danthron activates AMP-activated protein kinase and regulates lipid and glucose metabolism in vitro
期刊论文
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 8, 页码: 1061-1069
作者:
Zhou, Rong
;
Wang, Ling
;
Xu, Xing
;
Chen, Jing
;
Hu, Li-hong
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
1,8-dihydroxyanthraquinone (danthron)
traditional Chinese medicine
AMPK
SREBP1c
fatty acid synthetase
cholesterol
triglyceride
glucose consumption
danthronactivatesampactivatedproteinkinaseandregulateslipidandglucosemetabolisminvitro
期刊论文
actapharmacologicasinica, 2013, 卷号: 34, 期号: 8, 页码: 1061
作者:
Zhou Rong
;
Wang Ling
;
Xu Xing
;
Chen Jing
;
Hu Lihong
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
1
8-dihydroxyanthraquinone (danthron)
traditional Chinese medicine
AMPK
SREBP1c
fatty acid synthetase
cholesterol
triglyceride
glucose consumption
Evidence for an effect of clozapine on the regulation of fat-cell derived factors
期刊论文
Clinica Chimica Acta, 2009, 卷号: 408, 期号: 1-2, 页码: 98-104
作者:
Yang, Zhi
;
Yin, Ji-Ye
;
Gong, Zhi-Cheng
;
Huang, Qiong
;
Chen, Hao
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/03
PPARγ
peroxisome proliferator-activated receptor-γ
C/EBPα
CCAAT-enhancer binding protein
ADD1/SREBP1C
adipocyte determination and differentiation factor 1/sterol regulatory element binding protein
DGAT1
diacylglycerol acyltransferase1
LPL
lipoprotein lipase
PVDF
polyvinylidene difluoride
Clozapine
Rosiglitazone
Adipocyte
Fat-cell derived factors
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