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科研机构
上海药物研究所 [6]
中国科学院大学 [2]
复旦大学上海医学院 [1]
上海中医药大学 [1]
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期刊论文 [10]
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2019 [3]
2018 [2]
2013 [1]
2008 [2]
2006 [1]
2005 [1]
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Assay development for determination of DZ2002, a new reversible SAHH inhibitor, and its acid metabolite DZA in blood and application to rat pharmacokinetic study
期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2019, 卷号: 9, 期号: 1, 页码: 25-33
作者:
Jia, Weiwei
;
Li, Jing
;
Du, Feifei
;
Sun, Yan
;
Xu, Fang
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
S-adenosyl-L-homocysteine hydrolase
DZ2002
Carboxylesterases
Pharmacokinetics
Assay development for determination of DZ2002, a new reversible SAHH inhibitor, and its acid metabolite DZA in blood and application to rat pharmacokinetic study
期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2019, 卷号: 9, 期号: 1
作者:
Li, Chuan
;
Olaleye, Olajide E.
;
Chen, Danghui
;
Tang, Wei
;
Zuo, Jianping
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/12/05
S-adenosyl-L-homocysteine hydrolase
DZ2002
Carboxylesterases
Pharmacokinetics
assaydevelopmentfordeterminationofdz2002anewreversiblesahhinhibitoranditsacidmetabolitedzainbloodandapplicationtoratpharmacokineticstudy
期刊论文
药物分析学报英文版, 2019, 卷号: 009, 期号: 001, 页码: 25
作者:
Weiwei Jia
;
Jing Li
;
Feifei Du
;
Yan Sun
;
Fang Xu
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
S-adenosyl-L-homocysteine
hydrolase
DZ2002
Carboxylesterases
Pharmacokinetics
Topical administration of reversible SAHH inhibitor ameliorates imiquimod-induced psoriasis-like skin lesions in mice via suppression of TNF-alpha/IFN-gamma-induced inflammatory response in keratinocytes and T cell-derived IL-17
期刊论文
PHARMACOLOGICAL RESEARCH, 2018, 卷号: 129, 页码: 443-452
作者:
Lin, Ze-Min
;
Ma, Meng
;
Li, Heng
;
Qi, Qing
;
Liu, Yu-Ting
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/01/08
Reversible S-adenosyl-L-homocysteine
hydrolase inhibitor
Keratinocyte
Inflammation
Interleukin-17
Imiquimod
Psoriasis
Topical administration of reversible SAHH inhibitor ameliorates imiquimod-induced psoriasis-like skin lesions in mice via suppression of TNF-alpha/IFN-gamma-induced inflammatory response in keratinocytes and T cell-derived IL-17
期刊论文
PHARMACOLOGICAL RESEARCH, 2018, 卷号: 129
作者:
Lin, Ze-Min
;
Ma, Meng
;
Li, Heng
;
Qi, Qing
;
Liu, Yu-Ting
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Reversible S-adenosyl-L-homocysteine
hydrolase inhibitor
Keratinocyte
Inflammation
Interleukin-17
Imiquimod
Psoriasis
Critical role of transmethylation in TLR signaling and systemic lupus erythematosus
期刊论文
CLINICAL IMMUNOLOGY, 2013, 卷号: 147, 期号: 2, 页码: 133-143
作者:
Tardif, Virginie
;
Manenkova, Yulia
;
Berger, Michael
;
Hoebe, Kasper
;
Zuo, Jian-Ping
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Systemic lupus erythematosus
Transmethylation
S-adenosyl-L-homocysteine hydrolase
Toll-like receptors
Lymphocytes
Synthesis and biological evaluation of immunosuppressive agent DZ2002 and its stereoisomers
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 卷号: 16, 期号: 20, 页码: 9212-9216
作者:
Zhang, Yang-Ming
;
Ding, Yu
;
Tang, Wei
;
Luo, Wei
;
Gu, Min
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
DZ2002
stereoisomers
synthesis
immunosuppressive potency
S-adenosyl-L-homocysteine hydrolase
Down-regulation of s-adenosyl-l-homocysteine hydrolase reveals a role of cytokinin in promoting transmethylation reactions
期刊论文
Planta, 2008, 卷号: 228, 期号: 1, 页码: 125-136
作者:
Li, Chun-Hong
;
Yu, Nan
;
Jiang, Shi-Min
;
Shangguan, Xiao-Xia
;
Wang, Ling-Jian
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/05/10
Arabidopsis
Cytokinin
Dna methylation
S-adenosyl-l-homocysteine hydrolase
Advances in research of novel drugs based on S-adenosyl-L-homocysteine hydrolase as a potential target
期刊论文
Chinese Journal of Pharmacology and Toxicology, 2006, 卷号: 20, 期号: 6, 页码: 510-514
作者:
Fu Yufeng
;
Wu Qingli
;
Yang Yifu
;
Zuo Jianping
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
S-adenosyl-L-homocysteine hydrolase
autoimmune diseases
viruses
atherosclerosis
Alzheimer disease
Inhibitory effect of epimedium extract on s-adenosyl-l-homocysteine hydrolase and biomethylation
期刊论文
Life sciences, 2005, 卷号: 78, 期号: 2, 页码: 180-186
作者:
Zhang, XY
;
Li, YJ
;
Yang, XD
;
Wang, K
;
Ni, JZ
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/05/10
Epimedium extract
S-adenosyl-l-homocysteine hydrolase
Biomethylation
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