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Tepotinib reverses ABCB1-mediated multidrug resistance in cancer cells 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2019, 卷号: 166
作者:  Wu, Zhuo-Xun;  Teng, Qiu-Xu;  Cai, Chao-Yun;  Wang, Jing-Quan;  Lei, Zi-Ning
收藏  |  浏览/下载:17/0  |  提交时间:2019/12/05
Broad targeting of triptolide to resistance and sensitization for cancer therapy 期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:  Hou, Zhen-yan;  Tong, Xiao-pei;  Peng, Yong-bo;  Zhang, Bi-Kui*;  Yan, Miao*
收藏  |  浏览/下载:50/0  |  提交时间:2019/12/03
ABC  ATP-binding cassette  AKT  V-Akt murine thymoma viral oncogene homolog  ALDH1  aldehyde dehydrogenase 1  AR  androgen receptor  Bad  Bcl-2-associated death promoter  Bak  Bcl-2 homologous antagonist killer  Bax  Bcl-2-associated X protein  Bcl-2  B-cell lymphoma  Bcl-xL  Bcl-extra large  Bcl-xs  Bcl-extra short  BCRP  breast cancer resistance protein  Bid  BH3 interacting domain death agonist  Bik  Bcl-2-interacting killer  BNIP3  Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3  CAF  cancer-associated fibroblast  CAIX  carbonic anhydrase IX  cFLIP  cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein  ChIP  chromatin immunoprecipitation  CI  Combination Index  cIAP1/2  cellular IAP1/2  CML  chronic myelogenous leukemia  CSC  cancer stem cell  DISC  death-inducing signaling complex  DR  death receptor  DRI  Dose Reduction Index  ECM  extracellular matrix  EMT  epithelial-mesenchymal transition  EpCAM  epithelial cell adhesion molecule  GLUT  glucose transporter  GSK3β  glycogen synthase kinase-3β  HIF-1  hypoxia inducible factor-1  HSF1  heat shock factor 1  HSP  heat shock protein  IAP  inhibitor of apoptosis protein  JNK  c-JUN N-terminal kinase  MAPK  mitogen-activated protein kinase  Mcl-1  myeloid leukemia cell differentiation protein  MDM2  murine double minute 2  MDR  multidrug resistance  MKP  MAPK phosphatase  MRP1  multidrug resistance protein 1  NF-κB  nuclear factor-kappaB  pAkt  phosphor-Akt  PARP  poly ADP-ribose polymerase  P-gp  P-glycoprotein  PI3K-PTEN  phosphatidylinositol 3-kinase-phosphatase and tensin homolog  PKC  phosphorylated at Ser9 by protein kinase C  pp2A  protein phosphatase 2A  REST  repressor element-1 silencing transcription factor  SAR  structure-activity relationship  TAM  tumor-associated macrophage  TFIIH  transcription factor IIH  TKI  tyrosine kinase inhibitor  TM  tumor-microenvironment  TRAIL/Apo-2L  TNF-related apoptosis-inducing ligand  tRXRα  the N-terminal truncated form of the nuclear retinoid X receptor-α  TWHF  Tripterygium wilfordii Hook F  VEGF  vascular endothelial growth factor  XIAP  X-linked IAP  XPB  xerodermapigmentosum group B protein  Triptolide  Antineoplastic  Resistance  Sensitization  Mechanism  
Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance 期刊论文
European Journal of Medicinal Chemistry, 2017, 卷号: 135, 页码: 34-48
作者:  Zha, Gao-Feng;  Qin, Hua-Li*;  Youssif, Bahaa G. M.;  Amjad, Muhammad Wahab;  Raja, Maria Abdul Ghafoor
收藏  |  浏览/下载:14/0  |  提交时间:2019/12/04
Epidermal growth factor receptor (EGFR)  BRAF  Focal adhesion kinase (FAK)  Tubulin polymerization  Cancer cell lines  MDR  multidrug resistance  EGFR  epidermal growth factor receptor  EMEA  European Medicines Evaluation Agency  FDA  US Food and Drug Administration  NSCLC  non-small cell lung  FAK  focal adhesion kinase  RTK  receptor tyrosine kinases  MAPK  mitogen-activated protein kinase  ABC  ATP-binding cassette  NF-kB  NF-kappaB  FERM  Four-point-one, ezrin, radixin, moesin  TMP  Ligustrazine or tetramethylpyrazine  Adr  Adriamycin  DRS  death receptors  TFN  tumor necrosis factor  PI  propidium iodide  TKIs  tyrosine kinase inhibitors  FAR  fluorescence activity ratio  HRMS  high resolution mass spectra  TLC  thin layer chromatography  UV  ultraviolet  DMEM  Dulbecco's modified Eagle's medium  DMSO  dimethyl sulfoxide  IBX  2-iodoxybenzoic acid  
Extending the structure-activity relationship study of marine natural ningalin B analogues as P-glycoprotein inhibitors 期刊论文
2017, 卷号: 125, 页码: 795-806
作者:  Yang, Chao;  Wong, Iris L. K.;  Peng, Kai;  Liu, Zhen;  Wang, Peng
收藏  |  浏览/下载:6/0  |  提交时间:2020/01/03
Mouse ATP-Binding Cassette (ABC) Transporters Conferring Multi-Drug Resistance 期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2015, 卷号: 15, 期号: 4, 页码: 423-432
作者:  Li, Shuaizhang;  Zhang, Wen;  Yin, Xuejiao;  Xing, Shilai;  Xie, Heidi Qunhui
收藏  |  浏览/下载:182/0  |  提交时间:2016/03/10
Optimization of permethyl ningalin B analogs as P-glycoprotein inhibitors 期刊论文
2015, 卷号: 23, 期号: 17, 页码: 5566-5573
作者:  Wang, Zhen;  Wong, Iris L. K.;  Li, Fu Xing;  Yang, Chao;  Liu, Zhen
收藏  |  浏览/下载:3/0  |  提交时间:2020/01/13
Molecular cloning and expression analysis of PDR1-like gene in ginseng subjected to salt and cold stresses or hormonal treatment 期刊论文
Plant Physiology and Biochemistry, 2013, 卷号: 71, 页码: 203-211
作者:  Zhang, Ru;  Zhu, Jie;  Cao, Hong-Zhe;  An, Yan-Ru;  Huang, Jing-Jia
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/03
hABCF3, a TPD52L2 interacting partner, enhances the proliferation of human liver cancer cell lines in vitro 期刊论文
MOLECULAR BIOLOGY REPORTS, 2013, 卷号: 40, 期号: 10
作者:  Zhou, Juan;  Lin, Ying;  Shi, Huili;  Huo, Keke;  Li, Yanhong
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/19
OSI-930 analogues as novel reversal agents for ABCG2-mediated multidrug resistance 期刊论文
Biochemical Pharmacology, 2012, 卷号: 84, 期号: 6, 页码: 766-774
作者:  Ye-Hong Kuang;  Jay P. Patel;  Kamlesh Sodani;  Chung-Pu Wu;  Li-Qiu Liao
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/03
cDNA cloning and expression profile analysis of an ATP-binding cassette transporter in the hepatopancreas and intestine of shrimp Fenneropenaeus chinensis 期刊论文
AQUACULTURE, 2012, 卷号: 356, 页码: 250-255
作者:  Chang, Zhi-Qiang[1];  Li, Jian[2];  Liu, Ping[3];  Kuo, Mario Meng-Chiang[4];  He, Yu-Ying[5]
收藏  |  浏览/下载:3/0  |  提交时间:2020/01/02


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