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中南大学 [7]
中国医学科学院 北京... [2]
南华大学 [1]
中国水产科学院 [1]
武汉大学 [1]
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期刊论文 [16]
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2019 [1]
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Tepotinib reverses ABCB1-mediated multidrug resistance in cancer cells
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2019, 卷号: 166
作者:
Wu, Zhuo-Xun
;
Teng, Qiu-Xu
;
Cai, Chao-Yun
;
Wang, Jing-Quan
;
Lei, Zi-Ning
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/05
Tepotinib
Multidrug resistance (MDR)
ATP-binding cassette (ABC) transporter
ABCB1
Tyrosine kinase inhibitor
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance
期刊论文
European Journal of Medicinal Chemistry, 2017, 卷号: 135, 页码: 34-48
作者:
Zha, Gao-Feng
;
Qin, Hua-Li*
;
Youssif, Bahaa G. M.
;
Amjad, Muhammad Wahab
;
Raja, Maria Abdul Ghafoor
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/04
Epidermal growth factor receptor (EGFR)
BRAF
Focal adhesion kinase (FAK)
Tubulin polymerization
Cancer cell lines
MDR
multidrug resistance
EGFR
epidermal growth factor receptor
EMEA
European Medicines Evaluation Agency
FDA
US Food and Drug Administration
NSCLC
non-small cell lung
FAK
focal adhesion kinase
RTK
receptor tyrosine kinases
MAPK
mitogen-activated protein kinase
ABC
ATP-binding cassette
NF-kB
NF-kappaB
FERM
Four-point-one, ezrin, radixin, moesin
TMP
Ligustrazine or tetramethylpyrazine
Adr
Adriamycin
DRS
death receptors
TFN
tumor necrosis factor
PI
propidium iodide
TKIs
tyrosine kinase inhibitors
FAR
fluorescence activity ratio
HRMS
high resolution mass spectra
TLC
thin layer chromatography
UV
ultraviolet
DMEM
Dulbecco's modified Eagle's medium
DMSO
dimethyl sulfoxide
IBX
2-iodoxybenzoic acid
Extending the structure-activity relationship study of marine natural ningalin B analogues as P-glycoprotein inhibitors
期刊论文
2017, 卷号: 125, 页码: 795-806
作者:
Yang, Chao
;
Wong, Iris L. K.
;
Peng, Kai
;
Liu, Zhen
;
Wang, Peng
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
Ningalin B
Multidrug resistance (MDR)
P-glycoprotein (P-gp)
P-gp chemosensitizer
ATP-Binding cassette (ABC) transporter
Mouse ATP-Binding Cassette (ABC) Transporters Conferring Multi-Drug Resistance
期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2015, 卷号: 15, 期号: 4, 页码: 423-432
作者:
Li, Shuaizhang
;
Zhang, Wen
;
Yin, Xuejiao
;
Xing, Shilai
;
Xie, Heidi Qunhui
收藏
  |  
浏览/下载:182/0
  |  
提交时间:2016/03/10
ATP-binding cassette (ABC) transporter
cancer
inhibitors
multi-drug resistance
substrate
Optimization of permethyl ningalin B analogs as P-glycoprotein inhibitors
期刊论文
2015, 卷号: 23, 期号: 17, 页码: 5566-5573
作者:
Wang, Zhen
;
Wong, Iris L. K.
;
Li, Fu Xing
;
Yang, Chao
;
Liu, Zhen
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/13
Permethyl ningalin B
Multidrug resistance (MDR)
P-glycoprotein (P-gp)
P-gp chemosensitizer
ATP-binding cassette (ABC) transporter
Molecular cloning and expression analysis of PDR1-like gene in ginseng subjected to salt and cold stresses or hormonal treatment
期刊论文
Plant Physiology and Biochemistry, 2013, 卷号: 71, 页码: 203-211
作者:
Zhang, Ru
;
Zhu, Jie
;
Cao, Hong-Zhe
;
An, Yan-Ru
;
Huang, Jing-Jia
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/03
ABA
ABC
ATP-binding cassette
CaMV
DIG
Environmental stresses
GFP
Gene expression
Hormones
JA
MDR
MDR-associated protein
MRP
MS
MeJA
Murashige and Skoog
NBD
ORF
PDR
Panax ginseng
Pleiotropic drug resistance transporter
RACE
SA
SAR
TMD
abscisic acid
cauliflower mosaic virus
digoxigenin
green fluorescent protein
jasmonic acid
methyl jasmonate
multidrug resistance
nucleotide binding domain
open reading frame
pleiotropic drug resistance
qRT-RCR
quantitative real-time PCR
rapid-amplification of cDNA end
salicylic acid
systemic acquired resistance
transmembrane domain
hABCF3, a TPD52L2 interacting partner, enhances the proliferation of human liver cancer cell lines in vitro
期刊论文
MOLECULAR BIOLOGY REPORTS, 2013, 卷号: 40, 期号: 10
作者:
Zhou, Juan
;
Lin, Ying
;
Shi, Huili
;
Huo, Keke
;
Li, Yanhong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/19
ABC transporters
ATP-binding cassette (ABC)
Cell localization
Cell proliferation
hABCF3
Yeast-two-hybrid (Y2H)
OSI-930 analogues as novel reversal agents for ABCG2-mediated multidrug resistance
期刊论文
Biochemical Pharmacology, 2012, 卷号: 84, 期号: 6, 页码: 766-774
作者:
Ye-Hong Kuang
;
Jay P. Patel
;
Kamlesh Sodani
;
Chung-Pu Wu
;
Li-Qiu Liao
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
OSI-930
{N-(4-trifluoromethoxyphenyl)3-((quinolin-4-ylmethyl) amino) thiophene-2-carboxamide}
ABC
ATP binding cassette
ABCG2 (BCRP/MXR/ABCP)
ABC subfamily G member 2
MDR
multidrug resistance
P-gp
P-glycoprotein
ABCCs (MRPs)
ABC subfamily C member
RTK
receptor tyrosine kinases
KDR
kinase insert domain receptor
TKIs
tyrosine kinase inhibitors
IAAP
[125I]-iodoarylazidoprazosin
FTC
fumitremorgin C
MTT
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
DMSO
dimethylsulfoxide
OSI-930
ABC transporters
ABCG2
Multidrug resistance
cDNA cloning and expression profile analysis of an ATP-binding cassette transporter in the hepatopancreas and intestine of shrimp Fenneropenaeus chinensis
期刊论文
AQUACULTURE, 2012, 卷号: 356, 页码: 250-255
作者:
Chang, Zhi-Qiang[1]
;
Li, Jian[2]
;
Liu, Ping[3]
;
Kuo, Mario Meng-Chiang[4]
;
He, Yu-Ying[5]
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/02
ATP-binding cassette (ABC) transporters
Fenneropenaeus chinensis
pH
Norfloxacin
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