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上海药物研究所 [18]
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大连化学物理研究所 [6]
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Optogenetically engineered cell-based graphene transistor for pharmacodynamic evaluation of anticancer drugs
期刊论文
Sensors and Actuators B: Chemical, 2022, 卷号: 358, 页码: 1-11
作者:
Yang J(杨佳)
;
Li GX(李恭新)
;
Zu LP(祖立鹏)
;
Wang WX(王文学)
;
Ge ZX(葛治星)
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/03/07
Cell-based biosensor
Optogenetics
Photosensitive proteins
Cancer cells
Graphene transistor
Pharmacodynamic evaluation
Oxidosqualene Cyclases Involved in the Biosynthesis of Diverse Triterpenes in Camellia sasanqua
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2022
作者:
Huang, Liufang
;
Hu, Yonger
;
Huang, Ruoshi
;
Chen, Jiabo
;
Zhang, Xiande
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/07
oxidosqualene cyclases (OSCs)
Camellia sasanqua
triterpene biosynthesis
catalytic mechanism
Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity
期刊论文
XENOBIOTICA, 2021, 页码: 13
作者:
Sun, Dongxue
;
Gao, Xiaoxia
;
Wang, Qiao
;
Krausz, Kristopher W.
;
Fang, Zhongze
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  |  
浏览/下载:49/0
  |  
提交时间:2021/11/04
CYP
podophyllotoxin metabolism
liver microsomes
recombinant drug-metabolizing enzymes
hepatic and intestinal toxicity
Experimental and theoretical explorations of nanocarriers' multistep delivery performance for rational design and anticancer prediction
期刊论文
SCIENCE ADVANCES, 2021, 卷号: 7, 期号: 6, 页码: 15
作者:
Bao, Weier
;
Tian, Falin
;
Lyu, Chengliang
;
Liu, Bin
;
Li, Bin
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  |  
浏览/下载:27/0
  |  
提交时间:2021/03/29
DeepDRK: a deep learning framework for drug repurposing through kernel-based multi-omics integration
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 5
作者:
Wang, Yongcui
;
Yang, Yingxi
;
Chen, Shilong
;
Wang, Jiguang
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  |  
浏览/下载:31/0
  |  
提交时间:2021/11/18
drug repurposing
multi-omics data sources
kernel-based data integration
machine learning
cancer precision medicine
Engineering magnetosomes with chimeric membrane and hyaluronidase for efficient delivery of HIF-1 siRNA into deep hypoxic tumors
期刊论文
CHEMICAL ENGINEERING JOURNAL, 2020, 卷号: 398, 页码: 12
作者:
Lyu, Chengliang
;
Lu, Guihong
;
Bao, Weier
;
Li, Feng
;
Wang, Shuang
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/10/30
Tumor-macrophage chimeric cell membrane
Hyaluronidase
Small interfering RNA delivery
Hypoxia
Hypoxia-inducible factor-1
Marine bacterial surfactin CS30-2 induced necrosis-like cell death in Huh7.5 liver cancer cells
期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2020, 卷号: 38, 期号: 3, 页码: 826-833
作者:
Zhou Shengnan
;
Liu Ge
;
Wu Shimei
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  |  
浏览/下载:15/0
  |  
提交时间:2020/09/24
Bacillus
surfactin
anticancer activity
reactive oxygen species (ROS)
Laser ablation in liquids for the assembly of Se@Au chain-oligomers with long-term stability for photothermal inhibition of tumor cells
期刊论文
JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2020, 卷号: 566
作者:
Cai, Yunyu
;
Zhang, Yajun
;
Ji, Sihan
;
Ye, Yixing
;
Wu, Shouliang
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  |  
浏览/下载:64/0
  |  
提交时间:2020/11/26
Au nanoparticle
Se nanoparticle
Chain-oligomer
Laser ablation
Green synthesis
Photothermal therapy
Directional assembly
Bipolar interaction
Long-term stability
High photothermal transduction efficiency
An UHPLC-TOF-MS method for quantifying novel brominated anticancer compound bromophenol-thiosemicarbazone hybrid and its application to in vivo pharmacokinetic study
期刊论文
JOURNAL OF ANALYTICAL SCIENCE AND TECHNOLOGY, 2020, 卷号: 11, 期号: 1, 页码: 7
作者:
Li, Xiuxue
;
Wang, Lijun
;
Jia, Xiaoling
;
Guo, Chuanlong
;
Li, Chao
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/09/23
Novel compound
Quantitation
UHPLC-TOF-MS
Pharmacokinetics
(20S)-Protopanaxadiol Ginsenosides Induced Cytotoxicity via Blockade of Autophagic Flux in HGC-27 Cells
期刊论文
CHEMISTRY & BIODIVERSITY, 2020, 卷号: 17, 期号: 7
作者:
Han, Qingqing
;
Han, Lijuan
;
Tie, Fangfang
;
Wang, Zhenhua
;
Ma, Chengjun
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/11/25
(20S)-protopanaxadiol ginsenosides
autophagic flux
ginsenoside Rh2
lysosome
mitochondria
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