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科研机构
上海药物研究所 [44]
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期刊论文 [44]
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2020 [4]
2019 [3]
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Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 4, 页码: 483-498
作者:
Xu, Ming-ming
;
Ryan, Philip
;
Rudrawar, Santosh
;
Quinn, Ronald J.
;
Zhang, Hai-yan
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
Recent advances in dopaminergic strategies for the treatment of Parkinson's disease
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Mao, Qi
;
Qin, Wang-zhi
;
Zhang, Ao
;
Ye, Na
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
Parkinson's disease
dopamine
D-1 receptor
D-2 receptor
allosteric modulator
neuroprotection
multitarget
drug discovery and development
neurodegenerative diseases
advancesinthedevelopmentofimagingprobesandaggregationinhibitorsforalphasynuclein
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 4, 页码: 483
作者:
Xu Mingming
;
Ryan Philip
;
Rudrawar Santosh
;
Quinn Ronald J
;
Zhang Haiyan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
Parkinson’s disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
recentadvancesindopaminergicstrategiesforthetreatmentofparkinsonsdisease
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 4, 页码: 471
作者:
Mao Qi
;
Qin Wangzhi
;
Zhang Ao
;
Ye Na
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Parkinson’s disease
dopamine
D_1 receptor
D_2 receptor
allosteric modulator
neuroprotection
multitarget
drug discovery and development
neurodegenerative diseases
Caffeic acid reduces A53T alpha-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease
期刊论文
PHARMACOLOGICAL RESEARCH, 2019, 卷号: 150, 页码: 14
作者:
Zhang, Yu
;
Wu, Qimei
;
Zhang, Lei
;
Wang, Qing
;
Yang, Zexian
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Caffeic acid
A53T
Parkinson's disease
Autophagy
JNK
Neuroprotective Effects of Ginseng Phytochemicals: Recent Perspectives
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 16, 页码: 20
作者:
Huang, Xing
;
Li, Ning
;
Pu, Yiqiong
;
Zhang, Tong
;
Wang, Bing
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
neuroprotective effects
ginseng
Alzheimer's disease
ginsenoside
Parkinson's disease
Identification of a New alpha-Synuclein Aggregation Inhibitor via Mass Spectrometry Based Screening
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 6, 页码: 2683-2691
作者:
Xu, Mingming
;
Loa-Kum-Cheung, Wendy
;
Zhang, Haiyan
;
Quinn, Ronald J.
;
Mellick, George D.
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
aggregation
mass spectrometry
screening
inhibitor
Nuclear Accumulation of Histone Deacetylase 4 (HDAC4) Exerts Neurotoxicity in Models of Parkinson's Disease
期刊论文
MOLECULAR NEUROBIOLOGY, 2017, 卷号: 54, 期号: 9, 页码: 6970-6983
作者:
Wu, Qimei
;
Yang, Xiaoyu
;
Zhang, Lei
;
Zhang, Yu
;
Feng, Linyin
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
HDAC4
alpha-Synuclein
Neuroprotection
Parkinson's disease
PKC
Chronic mild stress accelerates the progression of Parkinson's disease in A53T alpha-synuclein transgenic mice
期刊论文
EXPERIMENTAL NEUROLOGY, 2016, 卷号: 285, 页码: 61-71
作者:
Wu, Qimei
;
Yang, Xiaoyu
;
Zhang, Yu
;
Zhang, Lei
;
Feng, Linyin
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Chronic mild stress
Parkinson's disease
alpha-synuclein
Dopamine
Microglia
Association between cigarette smoking and Parkinson's disease: A meta-analysis
期刊论文
ARCHIVES OF GERONTOLOGY AND GERIATRICS, 2015, 卷号: 61, 期号: 3, 页码: 510-516
作者:
Li, Xiao
;
Li, Weihua
;
Liu, Guixia
;
Shen, Xu
;
Tang, Yun
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Cigarette smoking
Parkinson's disease
Meta-analysis
Pack-year
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