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北京大学 [15]

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期刊论文 [15]

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限定条件	专题：北京大学第一署名单位第一作者单位通讯作者单位

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	Conformational Flexibility of a Short Loop near the Active Site of the SARS-3CLpro is Essential to Maintain Catalytic Activity 期刊论文 SCIENTIFIC REPORTS, 2016 Li, Chunmei; Teng, Xin; Qi, Yifei; Tang, Bo; Shi, Hailing; Ma, Xiaomin; Lai, Luhua 收藏 \| 浏览/下载：19/0 \| 提交时间：2017/12/03 CORONAVIRUS 3C-LIKE PROTEASE SUBSTRATE-BINDING CRYSTAL-STRUCTURE DIMER INTERFACE PROTEINASE MECHANISM DIMERIZATION DISSOCIATION SIMULATIONS INHIBITOR
	The alteration in the architecture of a T-DNA insertion rice mutant osmtd1 is caused by up-regulation of MicroRNA156f 期刊论文 JOURNAL OF INTEGRATIVE PLANT BIOLOGY, 2015 Liu, Qing; Shen, Gezhi; Peng, Keqin; Huang, Zhigang; Tong, Jianhua; Kabir, Mohammed Humayun; Wang, Jianhui; Zhang, Jingzhe; Qin, Genji; Xiao, Langtao 收藏 \| 浏览/下载：6/0 \| 提交时间：2017/12/03 Oryza sativa OsmiR156f plant architecture protease inhibitor T-DNA insertion PLANT ARCHITECTURE TRANSCRIPTION FACTORS NEGATIVE REGULATION PROTEASE INHIBITOR SHOOT GRAVITROPISM BUD OUTGROWTH PHASE-CHANGE MONOCULM 1 ARABIDOPSIS GENE
	Maturation Mechanism of Severe Acute Respiratory Syndrome (SARS) Coronavirus 3C-like Proteinase 期刊论文 journal of biological chemistry, 2010 Li, Chunmei; Qi, Yifei; Teng, Xin; Yang, Zongchang; Wei, Ping; Zhang, Changsheng; Tan, Lei; Zhou, Lu; Liu, Ying; Lai, Luhua 收藏 \| 浏览/下载：2/0 \| 提交时间：2015/11/14 CRYSTAL-STRUCTURE DIMER INTERFACE SUBSTRATE-SPECIFICITY HIV-1 PROTEASE VIRUS DIMERIZATION INHIBITOR DESIGN DOMAIN POLYPROTEIN
	The oral toxicity of the transgenic Bt plus CpTI cotton pollen to honeybees (Apis mellifera) 期刊论文生态毒物学与环境安全, 2009 Liu, Biao; Shu, Chang; Xue, Kun; Zhou, Kexin; Li, Xiaogang; Liu, Doudou; Zheng, Yangping; Xu, Chongren 收藏 \| 浏览/下载：3/0 \| 提交时间：2015/11/12 Cotton Cry1Ac+CpTI gene Oral acute toxic effect Longevity Non-target Risk assessment BACILLUS-THURINGIENSIS TOXIN SOYBEAN TRYPSIN-INHIBITOR HYPOPHARYNGEAL GLANDS LEARNING PERFORMANCES PROTEINASE-INHIBITOR PROTEASE INHIBITOR CARABID BEETLE PESTICIDE USE SWEET CORN IMPACTS
	Prediction of binding for a kind of non-peptic HCVNS3 serine protease inhibitors from plants by molecular docking and MM-PBSA method 期刊论文生物有机化学与医药化学, 2007 Li, Xudong; Zhang, Wei; Qiao, Xuebin; Xu, Xiajjie 收藏 \| 浏览/下载：6/0 \| 提交时间：2015/11/11 MM-PBSA molecular dynamics docking polyphenol inhibitor HCVNS3 protease HEPATITIS-C VIRUS FREE-ENERGIES LIGAND INTERACTIONS NS3/4A PROTEASE OPTIMIZATION DERIVATIVES PROTEINASE STRATEGIES SUBSTRATE MODELS
	Quaternary structure, substrate selectivity and inhibitor design for SARS 3C-like proteinase 期刊论文 current pharmaceutical design, 2006 Lai, Luhua; Han, Xiaofeng; Chen, Hao; Wei, Ping; Huang, Changkang; Liu, Shiyong; Fan, Keqiang; Zhou, Lu; Liu, Zhenming; Pei, Jianfeng; Liu, Ying 收藏 \| 浏览/下载：5/0 \| 提交时间：2015/11/13 SARS 3C-like proteinase quaternary structure enzyme catalytic mechanism substrate selectivity inhibitor design ACUTE RESPIRATORY SYNDROME RHINOVIRUS 3C PROTEASE CORONAVIRUS MAIN PROTEINASE IMIDAZOLIUM ION-PAIR ACTIVE-SITE 2-PYRIDONE-CONTAINING PEPTIDOMIMETICS ANALYTICAL ULTRACENTRIFUGATION IRREVERSIBLE INHIBITORS BIOLOGICAL EVALUATION GENOME SEQUENCE
	Antiviral compounds and one new iridoid glycoside from Cornus officinalis 期刊论文 progress in natural science, 2006 Wang, Y; Li, ZQ; Chen, LR; Xu, XJ 收藏 \| 浏览/下载：6/0 \| 提交时间：2015/11/16 inhibitor HCVNS3 protease iridoid glycoside Cornus officinalis Sieb. et Zucc VIRUS SERINE-PROTEASE HCVNS3 PROTEASE NS3/4A PROTEASE INHIBITORS CHINESE
	The N-terminal octapeptide acts as a dimerization inhibitor of SARS coronavirus 3C-like proteinase 期刊论文生物化学与生物物理学研究通讯, 2006 Wei, P; Fan, KQ; Chen, H; Ma, L; Huang, CK; Tan, L; Xi, D; Li, CM; Liu, Y; Cao, AN; Lai, LH 收藏 \| 浏览/下载：3/0 \| 提交时间：2015/11/11 SARS coronavirus 3C-like proteinase mutational study N-terminal peptide dimerization inhibitor peptide inhibitor Zhang-Poorman plot ACUTE-RESPIRATORY-SYNDROME LINKED INTERFACIAL PEPTIDES SMALL-MOLECULE INHIBITORS HIV-1 PROTEASE MAIN PROTEASE ANALYTICAL ULTRACENTRIFUGATION HUMAN-IMMUNODEFICIENCY CRYSTAL-STRUCTURES VIRUS PROTEASES 3CL PROTEASE
	The interaction between severe acute respiratory syndrome coronavirus 3C-like proteinase and a dimeric inhibitor by capillary electrophoresis 期刊论文分析生物化学, 2005 Ding, L; Zhang, XX; Wei, P; Fan, KQ; Lai, LH 收藏 \| 浏览/下载：3/0 \| 提交时间：2015/11/11 binding constants capillary electrophoresis interface inhibitor SARS 3C-like proteinase thermodynamic parameters MAIN PROTEINASE SERUM-ALBUMIN SARS BINDING DESIGN SUBSTRATE PROTEASE
	Temperature dependent protease activity and structural properties of human HtrA2 protease 期刊论文 biochemistry moscow, 2004 Zhang, XF; Chang, ZY 收藏 \| 浏览/下载：2/0 \| 提交时间：2015/11/16 HtrA2 protease temperature proteolytic activity structural change HUMAN SERINE-PROTEASE HEAT-SHOCK PROTEASE ESCHERICHIA-COLI CONFORMATIONAL-CHANGES APOPTOSIS PROTEINS CASPASE ACTIVITY INHIBITOR CHAPERONE OMI/HTRA2 INTERACTS

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