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上海药物研究所 [6]
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期刊论文 [38]
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Activation and function of receptor tyrosine kinases in human clear cell renal cell carcinomas
期刊论文
BMC CANCER, 2019, 卷号: 19, 期号: 1, 页码: 13
作者:
Zhang, Qing
;
Liu, Jian-He
;
Liu, Jing-Li
;
Qi, Chun-Ting
;
Yan, Lei
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2020/07/01
Receptor tyrosine kinases (RTKs)
Activation and function
Clear cell renal cell carcinomas (ccRCCs)
Targeted therapy
PDGFR beta
Stroma cells
Survivin-targeting miR-542-3p overcomes HER3 signaling-induced chemoresistance and enhances the antitumor activity of paclitaxel against HER2-overexpressing breast cancer
期刊论文
Cancer Letters, 2018, 卷号: 420, 页码: 97-108
作者:
Lyu, Hui
;
Wang, Shuiliang
;
Huang, Jingcao
;
Wang, Bolun
;
He, Zhimin
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/03
HER3
Survivin
miRNA
Paclitaxel resistance
Breast cancer
RTKs
Receptor tyrosine kinases
PI-3K
Phosphoinositide 3-kinase
CHX
Cycloheximide
ELISA
Enzyme-linked immunosorbent assay
IHC
Immunohistochemistry
i.p.
Intraperitoneal
Efficacy and safety of rituximab in the treatment of refractory myasthenia gravis: Meta-analysis
期刊论文
Chinese Journal of Contemporary Neurology and Neurosurgery, 2018, 卷号: Vol.18 No.7, 页码: 494-500
作者:
Shan-shan CHU
;
Deng CHEN
;
Li-na ZHU
;
Ge TAN
;
Da XU
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/02/25
Myasthenia
gravis
Receptors,
cholinergic
Receptor
protein
⁃
tyrosine
kinases
Meta⁃analysis
Efficacy and safety of rituximab in the treatment of refractory myasthenia gravis: Meta-analysis
期刊论文
Chinese Journal of Contemporary Neurology and Neurosurgery, 2018, 卷号: Vol.18 No.7, 页码: 494-500
作者:
Shan-shan CHU
;
Deng CHEN
;
Li-na ZHU
;
Ge TAN
;
Da XU
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/02/25
Myasthenia
gravis
Receptors,
cholinergic
Receptor
protein
⁃
tyrosine
kinases
Meta⁃analysis
Concomitant inhibition of receptor tyrosine kinases and downstream AKT synergistically inhibited growth of KRAS/BRAF mutant colorectal cancer cells
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 3, 页码: 5003-5015
作者:
Song, Qiaoling
;
Sun, Xiaoxiao
;
Guo, Hui
;
Yu, Qiang
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
receptor tyrosine kinases
AKT
colorectal cancer
drug combination
RAS/RAF
Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance
期刊论文
European Journal of Medicinal Chemistry, 2017, 卷号: 135, 页码: 34-48
作者:
Zha, Gao-Feng
;
Qin, Hua-Li*
;
Youssif, Bahaa G. M.
;
Amjad, Muhammad Wahab
;
Raja, Maria Abdul Ghafoor
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/04
Epidermal growth factor receptor (EGFR)
BRAF
Focal adhesion kinase (FAK)
Tubulin polymerization
Cancer cell lines
MDR
multidrug resistance
EGFR
epidermal growth factor receptor
EMEA
European Medicines Evaluation Agency
FDA
US Food and Drug Administration
NSCLC
non-small cell lung
FAK
focal adhesion kinase
RTK
receptor tyrosine kinases
MAPK
mitogen-activated protein kinase
ABC
ATP-binding cassette
NF-kB
NF-kappaB
FERM
Four-point-one, ezrin, radixin, moesin
TMP
Ligustrazine or tetramethylpyrazine
Adr
Adriamycin
DRS
death receptors
TFN
tumor necrosis factor
PI
propidium iodide
TKIs
tyrosine kinase inhibitors
FAR
fluorescence activity ratio
HRMS
high resolution mass spectra
TLC
thin layer chromatography
UV
ultraviolet
DMEM
Dulbecco's modified Eagle's medium
DMSO
dimethyl sulfoxide
IBX
2-iodoxybenzoic acid
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:
Yang, Xin
;
Xu, Zhipeng
;
Zhang, Chunlan
;
Cai, Zixin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/12/03
A1c
glycated hemoglobin
AACE
American Association of Clinical Endocrinologists
ACC
acetyl-CoA carboxylase
ADA
American Diabetes Association
Akt/PKB
tyrosine kinase/protein kinase B
AMP
adenosine monophosphate
AMPK
adenosine monophosphate-activated protein
Ang II
angiotensin II
ATP
adenosine triphosphate
BAT
brown adipose tissue
CHOP
CEBP-homologous protein
CEBP
CCAAT enhancer binding protein
CoA
coenzyme A
DPP
Diabetes Prevention Program
EASD
European Association for the Study of Diabetes
eNOS
endothelial nitric oxide synthase
ER
endoplasmic reticulum
FDA
Food and Drug Administration
FFA
free fatty acid
FOXO1
forkhead box protein O1
G6P
glucose 6-phosphate
GDM
gestational diabetes mellitus
GIPR
glucose-dependent insulinotropic polypeptide receptor
GLP-1R
glucagon-like peptide-1 receptor
GLUT1
glucose transporter-1
GLUT4
glucose transporter type 4
GLUTs
glucose transporters
G6P
glucose 6-phosphate, glucose transporter-1
GPR40
G protein-coupled receptor 40
HbA1c
hemoglobin A1c
HGP
hepatic glucose production
HSL
hormone sensitive lipase
IL-6
interleukin 6
INS-1
insulinoma cells in rat
IR
insulin resistance
IRS-1
insulin receptor substrate 1
JNK
c-Jun. N-terminal kinase
Kir6.2
inwardly rectifying potassium/kalium channel
LDs
lipid droplets
LDL
low density lipoprotein
LV
left ventricular
MIN6 cells
mouse insulinoma cells
MAPK
mitogen-activated protein kinases
mPTP
mitochondrial permeability transition pore opening
mTOR
mammalian target of rapamycin
NADPH
nicotinamide adenine dinucleotide phosphate
NF-kappaB
nuclear factors-kappa B
NIT-1 cells
insulinoma cells
p70S6K
p70 ribosomal S6 kinase
PA
palmitic acid
NOS
NADPH oxidase
p38 MAPK
p38 mitogen-activated protein kinase
PA
palmitic acid
PCOS
polycystic ovary syndrome
PGC-1α
peroxisome proliferator-activated receptor-g coactivator-1α
PI3K
phosphatidylinositol 3-kinase
PKB
protein kinase B
PKC
protein kinase C
PPARα
peroxisome-proliferator activated receptor α
PTP
permeability transition pore
RCT
randomized controlled trial
RISK
reperfusion injury salvage kinase
ROS
reactive oxygen species
SERCA2
reticulum sarcoplasmic Ca2 +-ATPase
RISK
reperfusion injury salvage kinase
Smad3
mothers against decapentaplegic homolog 3
SRC-2
steroid receptor coactivator 2
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TGFβ1
transforming growth factor β1
TLR4
Toll-like receptor
TNF-α
tumor necrosis factor α
TR4
testicular receptor 4
UKPDS
United Kingdom Prospective Diabetes Study
VLDL
very low density lipoprotein
Metformin
Pancreatic β Cells
Heart failure
Insulin sensitizer
Targeting receptor tyrosine kinase EphB4 in cancer therapy.
期刊论文
Seminars in cancer biology, 2017
作者:
Chen Yinnan
;
Zhang Hongmei
;
Zhang Yanmin
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/11/26
Ephrin signaling
Receptor tyrosine kinases
Drug target
Cancer therapy
EphB4 receptor
Suppression of Spry4 enhances cancer stem cell properties of human MDA-MB-231 breast carcinoma cells
期刊论文
CANCER CELL INTERNATIONAL, 2016, 卷号: 16
作者:
Hua, Shucheng
;
Jing, Hongyu
;
Liaw, Lucy
;
Friesel, Robert
;
Vary, Calvin
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
Sprouty4 (Spry4)
Cancer stem cells
Beta3-integrin (CD61)
CD133
Receptor tyrosine kinases (RTK)
Increased expression of EHF contributes to thyroid tumorigenesis through transcriptionally regulating HER2 and HER3
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: [db:dc_citation_issue], 页码: 57978-57990
作者:
Lv, Yanyan
;
Sui, Fang
;
Ma, Jingjing
;
Ren, Xiaojuan
;
Yang, Qi
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/02
EHF
PI3K/Akt pathway
thyroid cancer
HER family of receptor tyrosine kinases
MAPK pathway
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