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科研机构
上海药物研究所 [27]
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期刊论文 [27]
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2020 [1]
2019 [2]
2016 [1]
2014 [2]
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Pharmacolo... [2]
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Discovery of a 2-pyridinyl urea-containing compound YD57 as a potent inhibitor of apoptosis signal-regulating kinase 1 (ASK1)
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 195, 页码: 13
作者:
Zhang, Shiyan
;
Huang, Chaoying
;
Lyu, Xilin
;
Wang, Peipei
;
Zang, Yi
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
ASK1
ASK2
Selectivity
Apoptosis
Cell cycle arrest
Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal -actinin-4 expression and stabilizing integrin-cytoskeleton linkage
期刊论文
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 页码: 16
作者:
He, Shijun
;
Liu, Xing
;
Lin, Zemin
;
Liu, Yuting
;
Gu, Lei
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
SAHH inhibitor
Lupus nephritis
-Actinin-4
Integrin-linked kinase
Integrin
Focal adhesion
Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal α-actinin-4 expression and stabilizing integrin-cytoskeleton linkage
期刊论文
Arthritis Research & Therapy, 2019, 卷号: 21, 期号: 1
作者:
He,Shijun
;
Liu,Xing
;
Lin,Zemin
;
Liu,Yuting
;
Gu,Lei
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2020/07/01
SAHH inhibitor
Lupus nephritis
α-Actinin-4
Integrin-linked kinase
Integrin
Focal adhesion
kappa Opioid receptor activation in different brain regions differentially modulates anxiety-related behaviors in mice
期刊论文
NEUROPHARMACOLOGY, 2016, 卷号: 110, 页码: 92-101
作者:
Wang, Yu-Jun
;
Hang, Ai
;
Lu, Yu-Chen
;
Long, Yu
;
Zan, Gui-Ying
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
kappa Opioid receptor
pERK1/2
Region-specific
Dual effects
Anxiety
CAMK1 Phosphoinositide Signal-Mediated Protein Sorting and Transport Network in Human Hepatocellular Carcinoma (HCC) by Biocomputation
期刊论文
CELL BIOCHEMISTRY AND BIOPHYSICS, 2014, 卷号: 70, 期号: 2, 页码: 1011-1016
作者:
Wang, Lin
;
Huang, Juxiang
;
Jiang, Minghu
;
Chen, Qingchun
;
Jiang, Zhenfu
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/01/08
CAMK1
Human hepatocellular carcinoma (HCC)
Phosphoinositide signal-mediated protein sorting and transport network
Biocomputation
Ergosterol peroxide from Cordyceps cicadae ameliorates TGF-beta 1-induced activation of kidney fibroblasts
期刊论文
PHYTOMEDICINE, 2014, 卷号: 21, 期号: 3, 页码: 372-378
作者:
Zhu, Rong
;
Zheng, Rong
;
Deng, Yueyi
;
Chen, Yiping
;
Zhang, Shuwei
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Ergosterol peroxide
Cordyceps cicadae
TGF-beta 1
Chronic kidney disease
Fibroblast-to-myofibroblast transdifferentiaton
Huperzine A Improves Chronic Inflammation and Cognitive Decline in Rats With Cerebral Hypoperfusion
期刊论文
JOURNAL OF NEUROSCIENCE RESEARCH, 2010, 卷号: 88, 期号: 4, 页码: 807-815
作者:
Wang, Juan
;
Zhang, Hai Yan
;
Tang, Xi Can
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
cerebral hypoperfusion
huperzine A
chronic hypoxia
inflammation
white matter
Expression pattern of neural synaptic plasticity marker-Arc in different brain regions induced by conditioned drug withdrawal from acute morphine-dependent rats
期刊论文
ACTA PHARMACOLOGICA SINICA, 2009, 卷号: 30, 期号: 3, 页码: 282-290
作者:
Li, Mu
;
Hou, Yuan-yuan
;
Lu, Bin
;
Chen, Jie
;
Chi, Zhi-qiang
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
negative reinforcing effects
withdrawal
conditioned place aversion
Arc
prefrontal cortex
striatum
amygdala
rats
(5R)-5-hydroxytriptolide inhibits the immune response of human peripheral blood mononuclear cells
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2009, 卷号: 9, 期号: 1, 页码: 63-69
作者:
Zhou, Ru
;
Tang, Wei
;
He, Pei-Lan
;
Yang, Yi-Fu
;
Li, Yuan-Chao
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
(5R)-5-hydroxytriptolide
Cytokine
MAPK
PBMC
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