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科研机构
上海药物研究所 [16]
内容类型
期刊论文 [16]
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2022 [1]
2021 [1]
2020 [2]
2018 [4]
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Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2022, 卷号: 1867, 期号: 2, 页码: 13
作者:
Lu, Dasheng
;
Liu, Yameng
;
Luo, Yuhong
;
Zhao, Jie
;
Feng, Chao
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2022/01/18
Fatty acid oxidation
Acylcarnitines
FXR
FGF15/19
PGC1 alpha
Transcriptomics
Metabolomics
DOT1L Regulates Thermogenic Adipocyte Differentiation and Function via Modulating H3K79 Methylation
期刊论文
DIABETES, 2021, 卷号: 70, 期号: 6, 页码: 1317-1333
作者:
Shuai, Lin
;
Li, Bo-Han
;
Jiang, Hao-Wen
;
Yang, Lin
;
Li, Jia
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/17
Antispasmodic Drug Drofenine as an Inhibitor of Kv2.1 Channel Ameliorates Peripheral Neuropathy in Diabetic Mice
期刊论文
ISCIENCE, 2020, 卷号: 23, 期号: 10, 页码: 56
作者:
Xu, Xiaoju
;
Xu, Xu
;
Hao, Yanping
;
Zhu, Xialin
;
Lu, Jian
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
Pyrazolone derivative C29 protects against HFD-induced obesity in mice via activation of AMPK in adipose tissue
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Li, Bo-han
;
Zhang, Mei
;
Duan, Ya-nan
;
Shuai, Lin
;
Jiang, Hao-wen
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2020/12/21
AMP-activated protein kinase
pyrazolone derivative C29
obesity
energy expenditure
thermogenesis
inguinal white adipose tissue
white adipose browning
HS218 as an FXR antagonist suppresses gluconeogenesis by inhibiting FXR binding to PGC-1 alpha promoter
期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2018, 卷号: 85, 页码: 126-138
作者:
Xu, Xin
;
Shi, Xiaofan
;
Chen, Yidi
;
Zhou, Tingting
;
Wang, Jiaying
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
T2DM
Gluconeogenesis
FXR antagonist
PGC-1 alpha
Drug lead compound
Discovery of 1,8-acridinedione derivatives as novel GCN5 inhibitors via high throughput screening
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 740-751
作者:
Xiong, Huan
;
Han, Jie
;
Wang, Jun
;
Lu, Wenchao
;
Wang, Chen
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Epigenetics
Histone acetyltransferase
GCN5
High throughput screening
1,8-Acridinedione derivative
The PGC-1 alpha Activator ZLN005 Ameliorates Ischemia-Induced Neuronal Injury In Vitro and In Vivo
期刊论文
CELLULAR AND MOLECULAR NEUROBIOLOGY, 2018, 卷号: 38, 期号: 4, 页码: 929-939
作者:
Xu, Yazhou
;
Kabba, John Alimamy
;
Ruan, Wenchen
;
Wang, Yunjie
;
Zhao, Shunyi
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/01/08
Ischemic stroke
PGC-1 alpha
HO-1
Neuroprotection
AMP-Activated Protein Kinase (AMPK) Regulates Energy Metabolism through Modulating Thermogenesis in Adipose Tissue
期刊论文
FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9
作者:
Wu, Lingyan
;
Zhang, Lina
;
Li, Bohan
;
Jiang, Haowen
;
Duan, Yanan
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/01/08
AMP-activated protein kinase
thermogenesis
energy metabolism
A-769662
white adipose browning
PGC-1 alpha
Cucurbitane Glucosides from the Crude Extract of Siraitia grosvenorii with Moderate Effects on PGC-1 alpha Promoter Activity
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 5, 页码: 1428-1435
作者:
Niu, Biao
;
Ke, Chang-Qiang
;
Li, Bo-Han
;
Li, Yuanyuan
;
Yi, Yongji
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Yhhu981, a novel compound, stimulates fatty acid oxidation via the activation of AMPK and ameliorates lipid metabolism disorder in ob/ob mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 3, 页码: 343-352
作者:
Zeng, Hong-liang
;
Huang, Su-ling
;
Xie, Fu-chun
;
Zeng, Li-min
;
Hu, You-hong
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
yhhu981
fatty acid oxidation
fatty acid synthesis
AMPK
compound C
sirtinol
EX527
STO609
AICAR
metformin
metabolism disorder
C2C12 myotubes
HepG2 cells
ob/ob mice
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