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浏览/检索结果: 共10条，第1-10条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 HS218 as an FXR antagonist suppresses gluconeogenesis by inhibiting FXR binding to PGC-1α promoter 期刊论文 Metabolism: clinical and experimental, 2018, 卷号: 85, 页码: 126-138 作者:  Xu, Xin;  Shi, Xiaofan;  Chen, Yidi;  Zhou, Tingting;  Wang, Jiaying 收藏  |  浏览/下载：69/0  |  提交时间：2019/01/08 HS218 as an FXR antagonist suppresses gluconeogenesis by inhibiting FXR binding to PGC-1 alpha promoter 期刊论文 METABOLISM-CLINICAL AND EXPERIMENTAL, 2018, 卷号: 85, 页码: 126-138 作者:  Xu, Xin;  Shi, Xiaofan;  Chen, Yidi;  Zhou, Tingting;  Wang, Jiaying 收藏  |  浏览/下载：5/0  |  提交时间：2020/07/01 T2DM  Gluconeogenesis  FXR antagonist  PGC-1 alpha  Drug lead compound   Synthesis and biological evaluations of chalcones, flavones and chromenes as farnesoid x receptor (FXR) antagonists 期刊论文 2017, 卷号: 129, 页码: 303-309 作者:  Zhang, Guoning;  Liu, Shuainan;  Tan, Wenjuan;  Verma, Ruchi;  Chen, Yuan 收藏  |  浏览/下载：2/0  |  提交时间：2020/01/03 Farnesoid X receptor  Antagonist  Chalcones  Chromenes   Design, synthesis and metabolic regulation effect of farnesoid X receptor (FXR) antagonistic benzoxepin-5-ones 期刊论文 2017, 卷号: 28, 期号: 7, 页码: 1519-1522 作者:  Zhang, Guo-Ning;  Huan, Yi;  Wang, Xing;  Sun, Su-Juan;  Shen, Zhu-Fang 收藏  |  浏览/下载：3/0  |  提交时间：2020/01/04 Farnesoid X receptor  Antagonist  Benzoxepin-5-one  Triglyceride  Plasma ALT   Discovery of Farnesoid X Receptor Antagonists Based on a Library of Oleanolic Acid 3-O-Esters through Diverse Substituent Design and Molecular Docking Methods 期刊论文 2017, 卷号: 22, 期号: 5 作者:  Wang Shao-Rong;  Xu Tingting;  Deng Kai;  Wong Chi-Wai;  Liu Jinsong 收藏  |  浏览/下载：4/0  |  提交时间：2020/01/04 FXR antagonist  oleanolic acid  compound diversity  library design  molecular modeling   Discovery and SAR study of 3-(tert-butyl)-4-hydroxyphenyl benzoate and benzamide derivatives as novel farnesoid X receptor (FXR) antagonists 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 19, 页码: 6427-6436 作者:  Song, Kebiao;  Xu, Xing;  Liu, Peng;  Chen, Lili;  Shen, Xu 收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 FXR  FXR antagonist  SAR study  Non-steroidal   Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor alpha (FXR alpha) in Stabilizing the Homodimerization of the Receptor 期刊论文 JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 卷号: 290, 期号: 32, 页码: 19888-19899 作者:  Xu, Xing;  Xu, Xin;  Liu, Peng;  Zhu, Zhi-yuan;  Chen, Jing 收藏  |  浏览/下载：10/0  |  提交时间：2019/01/08 Design, Synthesis, and Biological Evaluation of Novel Nonsteroidal FarnesoidX Receptor (FXR) Antagonists: Molecular Basis of FXR Antagonism 期刊论文 CHEMMEDCHEM, 2015, 卷号: 10, 期号: 7, 页码: 1184-1199 作者:  Huang, Huang;  Si, Pei;  Wang, Lei;  Xu, Yong;  Xu, Xin 收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08 antagonists  mechanism of action  molecular dynamics  nonsteroidal ligands  receptors   Discovery and SAR study of hydroxyacetophenone derivatives as potent, non-steroidal farnesoid X receptor (FXR) antagonists 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 5, 页码: 1596-1607 作者:  Liu, Peng;  Xu, Xing;  Chen, Lili;  Ma, Lei;  Shen, Xu 收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 FXR antagonist  SAR study  Hydroxyacetophenone derivatives  Non-steroidal   Identification of 15d-PGJ(2) as an antagonist of farnesoid X receptor: Molecular modeling with biological evaluation 期刊论文 STEROIDS, 2013, 卷号: 78, 期号: 9, 页码: 813-822 作者:  Xu, Xing;  Lul, Yin;  Chen, Lili;  Chen, Jing;  Luo, Xiaomin 收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08 15-Deoxy-Delta(12,14)PGJ(2)  Farnesoid X receptor  Antagonist  Molecular dynamics simulation