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兰州大学 [12]
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期刊论文 [12]
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专题:兰州大学
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Molecular mechanism of R-bicalutamide switching from androgen receptor antagonist to agonist induced by amino acid mutations using molecular dynamics simulations and free energy calculation
期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2016, 卷号: 30, 期号: 1-12, 页码: 1189-1200
作者:
Liu, HL
;
Han, R
;
Li, JZ
;
Liu, HX
;
Zheng, LF
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/05/09
R-bicalutamide
Androgen receptor antagonist
Molecular dynamics simulations
MM-GBSA
Drug-resistant mechanism
Effects of the cannabinoid 1 receptor peptide ligands hemopressin, (m)RVD-hemopressin(alpha) and (m)VD-hemopressin(alpha) on memory in novel object and object location recognition tasks in normal young and Abeta1-42-treated mice.
期刊论文
NEUROBIOLOGY OF LEARNING AND MEMORY, 2016, 卷号: 134, 页码: 264-274
作者:
Zhang, Rui-San
;
He, Zhen
;
Jin, Wei-Dong
;
Wang, Rui
;
Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, 199 Donggang West Rd, Lanzhou 730000, Peoples R China.
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2017/01/10
Cannabinoid receptor
Hemopressin
(m)RVD-hemopressin(alpha)
(m)VD-hemopressin(alpha)
Recognition memory
Alzheimer's disease
Pharmacological characterization of EN-9, a novel chimeric peptide of endomorphin-2 and neuropeptide FF that produces potent antinociceptive activity and limited tolerance
期刊论文
NEUROPHARMACOLOGY, 2016, 卷号: 108, 页码: 364-372
作者:
Wang, ZL
;
Li, N
;
Wang, P
;
Tang, HH
;
Han, ZL
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/01/10
Chimeric peptide
Endomorphin-2
Neuropeptide FF
Opioid
Antinociception
Non-tolerance
Salusin beta Within the Nucleus Tractus Solitarii Suppresses Blood Pressure Via Inhibiting the Activities of Presympathetic Neurons in the Rostral Ventrolateral Medulla in Spontaneously Hypertensive Rats
期刊论文
CARDIOVASCULAR TOXICOLOGY, 2016, 卷号: 16, 期号: 3, 页码: 223-234
作者:
Li, HB
;
Lu, Y
;
Liu, JJ
;
Miao, YW
;
Zheng, TZ
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2017/01/10
Salusin
Nucleus tractus solitarii
Rostral ventrolateral medulla
Baroreflex
Presympathetic neuron
Role of histamine H1-receptor on behavioral states and wake maintenance during deficiency of a brain activating system: A study using a knockout mouse model
期刊论文
NEUROPHARMACOLOGY, 2016, 卷号: 106, 页码: 20-34
作者:
Parmentier, R
;
Zhao, Y
;
Perier, M
;
Akaoka, H
;
Lintunen, M
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2017/01/10
Wakefulness
Arousal
Sleep
Cortical activation
Histamine
H1-receptor
Knockout mice
EEG
Behavior
Cholinergic transmission
Compensation
Interaction mechanism exploration of R-bicalutamide/S-1 with WT/W741L AR using molecular dynamics simulations
期刊论文
MOLECULAR BIOSYSTEMS, 2015, 卷号: 11, 期号: 12, 页码: 3347-3354
作者:
Liu, HL
;
An, XL
;
Li, SY
;
Wang, YW
;
Li, JZ
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/01/11
In Silico Classification and Prediction of VIP Derivatives as VPAC1/VPAC2 Receptor Agonists/Antagonists
期刊论文
Combinatorial Chemistry & High Throughput Screening, 2015, 卷号: 18, 期号: 1, 页码: 33-41
作者:
Li, JZ
;
Wang, X
;
Liu, HX
;
Li, HY
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2015/12/29
Agonist
antagonist
classification
vasoactive intestinal polypeptide derivatives
Prostaglandin E-2 accelerates invasion by upregulating Snail in hepatocellular carcinoma cells
期刊论文
TUMOR BIOLOGY, 2014, 卷号: 35, 期号: 7, 页码: 7135-7145
作者:
Zhang, M
;
Zhang, H
;
Cheng, SY
;
Zhang, DC
;
Xu, Y
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/12/22
PGE(2)
EP4 receptor
Snail
NF-kappa B
Akt
Hepatoma cell
Antinociceptive Effects of Central Administration of the Endogenous Cannabinoid Receptor Type 1 Agonist VDPVNFKLLSH-OH [(m)VD-hemopressin(alpha)], an N-Terminally Extended Hemopressin Peptide
期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2014, 卷号: 348, 期号: 2, 页码: 316-323
作者:
Han, ZL
;
Fang, Q
;
Wang, ZL
;
Li, XH
;
Li, N
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/12/22
The GABA(B) Receptor Inhibits Activation of Hepatic Stellate Cells
期刊论文
DIGESTIVE DISEASES AND SCIENCES, 2010, 卷号: 55, 期号: 2, 页码: 261-267
作者:
Xiao, F
;
Yu, KK
;
Dong, F
;
Liang, YL
;
Jun, C
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/12/22
Hepatic stellate cell
Liver fibrogenesis
GABA(B) receptor
Extracellular matrix
TGF-beta 1
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