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科研机构
西安交通大学 [1]
中南大学 [1]
武汉大学 [1]
合肥物质科学研究院 [1]
内容类型
期刊论文 [4]
发表日期
2021 [1]
2018 [1]
2016 [1]
2015 [1]
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Constitutive BAK/MCL1 complexes predict paclitaxel and S63845 sensitivity of ovarian cancer
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12
作者:
Liu, Dongyan
;
Hou, Xiaonan
;
Wu, Wangyu
;
Zafagnin, Valentina
;
Li, Yunjian
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/09/06
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
BCL2-BH4 antagonist BDA-366 suppresses human myeloma growth
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: [db:dc_citation_issue], 页码: 27753-27763
作者:
Deng, Jiusheng
;
Park, Dongkyoo
;
Wang, Mengchang
;
Nooka, Ajay
;
Deng, Qiaoya
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/02
apoptosis
multiple myeloma
small molecule BDA-366
BCL2
MYBL2 guides autophagy suppressor VDAC2 in the developing ovary to inhibit autophagy through a complex of VDAC2-BECN1-BCL2L1 in mammals
期刊论文
AUTOPHAGY, 2015, 卷号: 11, 期号: 7
作者:
Yuan, Jia
;
Zhang, Ying
;
Sheng, Yue
;
Fu, Xiazhou
;
Cheng, Hanhua
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Beclin1
MYBL2
ovary
reproduction
transcription regulation
VDAC2
ATG5
autophagy-related 5
ATG12
autophagy-related 12
ATG16L1
autophagy-related 16-like 1
BAK
BCL2-antagonist
killer 1
BCL2
B-cell CLL
lymphoma 2
BCL2L1
BCL2-like 1
BECN1
Beclin 1
autophagy related
CDS
coding DNA sequence
Dpp
days postpartum
GATA1
GATA binding protein 1 (globin transcription factor 1)
GATA2
GATA binding protein 2
LC3B
microtubule-associated protein 1 light chain 3 beta
MBS
MYBL2 binding site
MYBL2
v-myb avian myeloblastosis viral oncogene homolog-like 2
SP1
Sp1 transcription factor
VDAC
voltage-dependent anion channel
wt
wild type
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