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Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis 期刊论文
Redox Biology, 2018, 卷号: 16, 页码: 32-46
作者:  Han, Yachun;  Xu, Xiaoxuan;  Tang, Chengyuan;  Gao, Peng;  Chen, Xianghui
收藏  |  浏览/下载:30/0  |  提交时间:2019/12/03
ALT  alanine aminotransferase  AST  aspartate aminotransferase  BUN  blood urea nitrogen  BW  body weight  BG  blood glucose  DCFDA  dichlorodihydrofluorescein diacetate  DN  diabetic nephropathy  ECL  enhanced chemiluminescence  EM  electron microscopy  EMT  epithelial–mesenchymal transition  HbA1C  hemoglobin A1c  HE  hematoxylin-eosin  IF  immunofluorescence  IHC  immunohistochemistry  KW  kidney weight  LDL  low-density lipoprotein  MDA  malondialdehyde  MFI  median fluorescence intensity  MMP  mitochondrial transmembrane potential  MMT  methyl methane-thiosulphonate  MPTP  mitochondrial permeability transition pore  MSU  monosodium urate  MtROS  mitochondria reactive oxygen species  PAS  periodic acid-Schiff  Scr  serum creatinine  TC  total cholesterol  TG  triglyceride  TBARS  thiobarbituric acid reactive substances  TPP  triphenylphosphonium  TRX  thioredoxin  TXNIP  thioredoxin-interacting protein  TUNEL  terminal deoxynucleotidyl transferase dUTP nick end-labeling  8-OHdG  8-oxo-deoxyguanosine  UA  uric acid  Diabetic nephropathy  Mitochondria  Reactive oxygen species (ROS)  TRX/TXNIP  NLRP3 inflammasome  MitoQ  
Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc 期刊论文
Redox Biology, 2017, 卷号: 13, 页码: 482-497
作者:  Yang, Shikun;  Zhao, Li;  Han, Yachun;  Liu, Yu;  Chen, Chao
收藏  |  浏览/下载:25/0  |  提交时间:2019/12/03
DN  diabetic nephropathy  ROS  reactive oxygen species  HG  high-glucose  SIRT1  sirtuin-1  Ac-H3  acetyl-histone H3  STZ  streptozotocin  AMPK  AMP-activated protein kinase  ECM  extracellular matrix  Nox2  NADPH oxidase 2  EMT  tubular epithelial-mesenchymal transition  DAPI  4′,6-diamidino-2-phenylindole 9  DHE  dihydroethidium  NDRD  non-diabetic renal disease  H&E  hematoxylin-eosin  PAS  periodic acid-Schiff  PASM  periodic acid-silver methenamine  IHC  immunohistochemistry  MDA  malondialdehyde  ChIP  chromatin immunoprecipitation  TC  total cholesterol  BUN  blood urea nitrogen  FN  fibronectin  HBA1C  glycosylated hemoglobin  Scr  serum creatinine  TG  triglyceride  Probucol  Renal injury  Diabetic nephropathy  p66Shc  
Homogeneous synthesis of quaternized chitin in NaOH/urea aqueous solution as a potential gene vector 期刊论文
Carbohydrate Polymers, 2016, 卷号: 150, 页码: 180-186
作者:  Peng, Na;  Ai, Ziye;  Fang, Zehong;  Wang, Yanfeng;  Xia, Zhiping
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/03
Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3- (1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice 期刊论文
Cell and Tissue Research, 2016, 卷号: 363, 期号: 2, 页码: 399-409
作者:  Zhou, Yong;  Sun, Guo-Ying;  Liu, Tian;  Duan, Jia-Xi;  Zhou, Hui-Fang
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/03
A high-performance nonenzymatic piezoelectric sensor based on molecularly imprinted transparent TiO2 film for detection of urea 期刊论文
Biosensors and Bioelectronics, 2015, 卷号: 74, 页码: 85-90
作者:  Yang, Zheng-peng;  Liu, Xuan;  Zhang, Chun-jing*;  Liu, Bao-zhong
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/03
Combination of biological pretreatment with NaOH/Urea pretreatment at cold temperature to enhance enzymatic hydrolysis of rice straw 期刊论文
Bioresource Technology, 2015, 卷号: 198, 页码: 725-731
作者:  Dai, Youzhi;  Si, Mengying;  Chen, Yuehui*;  Zhang, Nianlei;  Zhou, Mo
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/03
Study on performance of a novel P(VDF-HFP)/SiO2 composite polymer electrolyte using urea as pore-forming agent 期刊论文
Ionics, 2014, 卷号: 20, 期号: 9, 页码: 1217-1224
作者:  Li, Yan;  Xiao, Wei;  Li, Xinhai*;  Miao, Chang;  Guo, Huajun
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/03
Influencing factors for saliva urea and its application in chronic kidney disease 期刊论文
Clinical Biochemistry, 2013, 卷号: 46, 期号: 3, 页码: 275-277
作者:  Peng, Can-hui;  Xia, Yun-cheng*;  Wu, Yong;  Zhou, Zhi-fang;  Cheng, Ping
收藏  |  浏览/下载:1/0  |  提交时间:2019/12/03
Design, synthesis and biological evaluation of di-substituted cinnamic hydroxamic acids bearing urea/thiourea unit as potent histone deacetylase inhibitors 期刊论文
Bioorganic and Medicinal Chemistry Letters, 2013, 卷号: 23, 期号: 23, 页码: 6432-6435
作者:  Ning, Chengqing;  Bi, Yanjing;  He, Yujun;  Huang, WenYuan;  Liu, Lifei
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/03
Single-enzyme nanoparticles based urea biosensor 期刊论文
Sensors and Actuators, B: Chemical, 2013, 卷号: 188, 页码: 313-317
作者:  Yang, Zhengpeng*;  Zhang, Chunjing
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/03


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