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Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis
Han, Yachun; Xu, Xiaoxuan; Tang, Chengyuan; Gao, Peng; Chen, Xianghui; Xiong, Xiaofen; Yang, Ming; Yang, Shikun; Zhu, Xuejing; Yuan, Shuguang
刊名Redox Biology
2018
卷号16页码:32-46
关键词ALT alanine aminotransferase AST aspartate aminotransferase BUN blood urea nitrogen BW body weight BG blood glucose DCFDA dichlorodihydrofluorescein diacetate DN diabetic nephropathy ECL enhanced chemiluminescence EM electron microscopy EMT epithelial–mesenchymal transition HbA1C hemoglobin A1c HE hematoxylin-eosin IF immunofluorescence IHC immunohistochemistry KW kidney weight LDL low-density lipoprotein MDA malondialdehyde MFI median fluorescence intensity MMP mitochondrial transmembrane potential MMT methyl methane-thiosulphonate MPTP mitochondrial permeability transition pore MSU monosodium urate MtROS mitochondria reactive oxygen species PAS periodic acid-Schiff Scr serum creatinine TC total cholesterol TG triglyceride TBARS thiobarbituric acid reactive substances TPP triphenylphosphonium TRX thioredoxin TXNIP thioredoxin-interacting protein TUNEL terminal deoxynucleotidyl transferase dUTP nick end-labeling 8-OHdG 8-oxo-deoxyguanosine UA uric acid Diabetic nephropathy Mitochondria Reactive oxygen species (ROS) TRX/TXNIP NLRP3 inflammasome MitoQ
ISSN号2213-2317
DOI10.1016/j.redox.2018.02.013
URL标识查看原文
WOS记录号WOS:000446404400003
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/3333934
专题中南大学
作者单位1.[Han, Yachun
2.Liu, Fuyou
3.Zhu, Xuejing
4.Gao, Peng
5.Yang, Shikun
6.Xiong, Xiaofen
7.Tang, Chengyuan
8.Yuan, Shuguang
9.Sun, Lin
10.Chen, Xianghui
推荐引用方式
GB/T 7714
Han, Yachun,Xu, Xiaoxuan,Tang, Chengyuan,et al. Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis[J]. Redox Biology,2018,16:32-46.
APA Han, Yachun.,Xu, Xiaoxuan.,Tang, Chengyuan.,Gao, Peng.,Chen, Xianghui.,...&Sun, Lin*.(2018).Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis.Redox Biology,16,32-46.
MLA Han, Yachun,et al."Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis".Redox Biology 16(2018):32-46.
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