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科研机构
上海药物研究所 [54]
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期刊论文 [53]
会议论文 [1]
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2021 [3]
2020 [4]
2019 [1]
2018 [2]
2017 [3]
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Huangjinsan ameliorates adenine-induced chronic kidney disease by regulating metabolic profiling
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 11
作者:
Guo, Yuejiao
;
Liu, Fang
;
Chen, MingCang
;
Tian, Qiang
;
Tian, Xiaoting
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/12/16
chronic kidney disease
Huangjinsan
metabolomics
renoprotection
traditional Chinese medicine
Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17
作者:
Xie, Hong-Xu
;
Zhang, Juan
;
Li, Yue
;
Zhang, Jin-He
;
Liu, Shan-Kui
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/11/04
Tetrahydrobenzo[b]thiophen-2-yl)urea
alpha-Glucosidase inhibitors
Non-competitive inhibitor
Molecular docking
Anti-hyperglycaemic activity
Type 2 diabetes
Deleterious mutation V369M in the mouse GCGR gene causes abnormal plasma amino acid levels indicative of a possible liver & ndash;alpha-cell axis
期刊论文
BIOSCIENCE REPORTS, 2021, 卷号: 41, 期号: 6, 页码: 12
作者:
Liu, Qiaofeng
;
Lin, Guangyao
;
Chen, Yan
;
Feng, Wenbo
;
Xu, Yingna
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/11/16
PPh3/I-2-catalyzed one-pot synthesis of 4,6-diarylpyrimidin-2(1H)-ones
期刊论文
SYNTHETIC COMMUNICATIONS, 2020, 页码: 8
作者:
Zhang, Yanzhi
;
Lei, Min
;
Xue, Kangsheng
;
Sun, Guoxiang
;
Zhou, Yang
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  |  
浏览/下载:18/0
  |  
提交时间:2020/12/21
46-diarylpyrimidin-2-(1H)-ones
PPh3
I2
Aldehyde
Ketone
Biginelli reaction
Design, Synthesis, and Biological Activities of Novel Triazolothiadiazole Derivatives Linked with Amino Side Chain Containing Urea Group as DOT1L Inhibitors
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 40, 期号: 8, 页码: 2450-2459
作者:
Liu Na
;
Guo Siqi
;
Liu Junfang
;
Chen Yantao
;
Xu Xiaoming
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/24
DOT1L inhibitor
triazolothiadiazole
triazolothiadiazine
nucleophilic substitution
Decomposition and kinetic studies of AdBlue using thermogravimetric and mass spectrometric (TG-MS) analyses
期刊论文
BIOMASS CONVERSION AND BIOREFINERY, 2020, 页码: 9
作者:
Li, Huidong
;
Yang, Liping
;
Tao, Ye
;
Luo, Caiyun
;
Cao, Chengcheng
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/12/24
AdBlue
Decomposition
Thermogravimetry
Mass spectrometer
Kinetic analysis
Discovery of a 2-pyridinyl urea-containing compound YD57 as a potent inhibitor of apoptosis signal-regulating kinase 1 (ASK1)
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 195, 页码: 13
作者:
Zhang, Shiyan
;
Huang, Chaoying
;
Lyu, Xilin
;
Wang, Peipei
;
Zang, Yi
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  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
ASK1
ASK2
Selectivity
Apoptosis
Cell cycle arrest
Improving Compliance and Decreasing Drug Accumulation of Diethylstilbestrol through Cocrystallization
期刊论文
CRYSTAL GROWTH & DESIGN, 2019, 卷号: 19, 期号: 3, 页码: 1942-1953
作者:
Li, Zhen
;
Li, Meiqi
;
Peng, Bo
;
Zhu, Bingqing
;
Wang, Jian-rong
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
Design, synthesis, and biological evaluation of 2-(phenoxyaryl)-3-urea derivatives as novel P2Y(1) receptor antagonists
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 302-310
作者:
Peng, Jingjing
;
Zhao, Lifen
;
Wang, Lanlan
;
Chen, Hui
;
Qiu, Yunguang
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/01/08
P2Y(1) receptor antagonist
2-(phenoxyaryl)-3-urea derivatives
Anti-Platelet
Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy
期刊论文
NEUROPHARMACOLOGY, 2018, 卷号: 130, 页码: 77-91
作者:
Guo, Xiaodan
;
Lv, Jianlu
;
Lu, Jian
;
Fan, Lei
;
Huang, Xi
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Ginseng
Autophagy
BACE1
ER stress
Amyloid beta
Apoptosis
APP/PS1 transgenic mice
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