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A pectin from fruits of Lycium barbarum L. decreases Beta-amyloid peptide production through modulating APP processing 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 201, 页码: 65-74
作者:  Zhou, Lishuang;  Liao, Wenfeng;  Zeng, Hui;  Yao, Yanli;  Chen, Xia
收藏  |  浏览/下载:153/0  |  提交时间:2019/01/08
Iron dysregulates APP processing accompanying with sAPP alpha cellular retention and beta-secretase inhibition in rat cortical neurons 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 2, 页码: 177-183
作者:  Chen, Yu-ting;  Chen, Wu-yan;  Huang, Xiao-tian;  Xu, Ye-chun;  Zhang, Hai-yan
收藏  |  浏览/下载:34/0  |  提交时间:2019/01/08
Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease 期刊论文
JOURNAL OF CONTROLLED RELEASE, 2018, 卷号: 279
作者:  Wang, Pengzhen;  Zheng, Xiaoyao;  Guo, Qian;  Yang, Peng;  Pang, Xiaoying
收藏  |  浏览/下载:50/0  |  提交时间:2019/12/05
Live or let die: Neuroprotective and anti-cancer effects of nutraceutical antioxidants 期刊论文
Pharmacology and Therapeutics, 2018, 卷号: 183, 页码: 137-151
作者:  Mao, Xiao-Yuan*;  Jin, Ming-Zhu;  Chen, Jin-Fei*;  Zhou, Hong-Hao;  Jin, Wei-Lin*
收藏  |  浏览/下载:13/0  |  提交时间:2019/12/03
PD  Parkinson's disease  AD  Alzheimer's disease  EGCG  (−)-Epigallocatechin-3-gallate  NRF2  NF-E2-related factor 2  ROS  reactive oxygen species  H2O2  hydrogen peroxide  ER  endoplasmic reticulum  GPX  glutathione-peroxidase  NOX  NADPH oxidases (NOXs)  LOX  lipoxygenases  ERK  extracellular signal-regulated kinase  JNK  c-Jun amino-terminal kinase  MAPK  mitogen-activated protein kinase  HNE  4-hydroxy-2-nonenol  ARE  antioxidant responsive element  GST  glutathione S-transferase  IFNγ  interferon-γ  LPS  lipopolysaccharide  SOD  superoxide dismutase  TNF-α  tumor necrosis factor-α  APP  β-amyloid precursor protein  SAM  S-adenosylmethionine  MAT  methionine adenosyltransferase  SAH  Sadenosyl homocysteine  MT  methyltransferases  BDNF  brain-derived neurotrophic factor  Nutraceuticals  Neuroprotection  Anti-cancer  ROS addiction  Ferroptosis  Oxidative stress  
Visualization of Alzheimer's Disease Related alpha-/beta-/gamma-Secretase Ternary Complex by Bimolecular Fluorescence Complementation Based Fluorescence Resonance Energy Transfer 期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018, 卷号: 11, 期号: 1, 页码: 431
作者:  Wang, Xin;  Pei, Gang
收藏  |  浏览/下载:28/0  |  提交时间:2019/04/28
Anti-inflammatory effects of bone marrow mesenchymal stem cells on mice with Alzheimer's disease 期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2018, 卷号: 16, 期号: 6, 页码: 5015-5020
作者:  Wei, Yan;  Xie, Zhaohong;  Bi, Jianzhong;  Zhu, Zhengyu
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/11
Amyloid precursor protein is overexpressed in bladder cancer and contributes to the malignant bladder cancer cell behaviors 期刊论文
INTERNATIONAL JOURNAL OF UROLOGY, 2018, 卷号: 25, 期号: 9, 页码: 808-816
作者:  Zhang, Dongqing;  Zhou, Changkuo;  Li, Yan;  Gao, Lijian;  Pang, Zhipeng
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/11
One-step synthesized flower-like materials used for sensitively detecting amyloid precursor protein 期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2018, 卷号: 410, 期号: 26, 页码: 6901-6909
作者:  Wang, Chengke[1];  Tan, Rong[2];  Wang, Qingqing[3]
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/24
Myelin injury in the central nervous system and Alzheimer's disease 期刊论文
Brain Research Bulletin, 2018, 卷号: 140, 页码: 162-168
作者:  Wang, Sha-Sha;  Zhang, Zhao;  Zhu, Tian-Bi;  Chu, Shi-Feng;  He, Wen-Bin
收藏  |  浏览/下载:28/0  |  提交时间:2019/12/27
OLG  oligodendrocyte  CNS  central nervous system  SC  Schwann cell  PNS  peripheral nervous system  MBP  myelin basic protein  PLP  proteolipid protein  P0/MPZ  myelin protein zero  EAE  experimental allergic encephalomyelitis  MS  multiple sclerosis  CNP  2′ 3′-cyclic nucleotide 3′-phosphodiesterase  MAG  myelin associated glycoprotein  MOG  myelin oligodendrocyte glycoprotein  AD  Alzheimer's disease  OPC  oligodendrocyte precursor cell  NPC  neural progenitor cell  ROS  reactive oxygen species  TNF  tumour necrosis factor  AIF  apoptosis-inducing factor  IFN-γ  interferon gamma  ERK1/2  extracellular signal-regulated kinases-1 and -2  MAPK  mediators of mitogen-activated protein kinase  FGFR1/2  fibroblast growth factor receptors-1 and -2  Dock3  dedicator of cytokinesis 3  PERK  pancreatic endoplasmic reticulum kinase  GEF  guanine nucleotide exchange factor  SIRT2  sirtuin 2  NOD2  Nucleotide-binding oligomerization domain containing protein 2  RIPK2  receptor-interacting serine/threonine kinase 2  Shh  Sonic Hedgehog  NMO  neuromyelitis optica  ADEM  acute disseminated encephalomyelitis  ANHLE  acute necrotizing hemorrhagic leukoencephalitis  CPM  central pontine myelinolysis    beta-amyloid  SP  senile plaque  NFT  neurofibrillary tangle  MRI  magnetic resonance imaging  Myelin  Oligodendrocyte  Demyelination  Neurodegenerative diseases  Alzheimer’s disease  
Effect of microenvironment on beta-site amyloid precursor protein cleaving enzyme 1 expression in PC12 Cells 期刊论文
Journal of Shanghai Jiaotong University .Medical Science, 2018, 卷号: 38, 期号: 9, 页码: 1005-1012
作者:  Yang Huanqing;  He Xiang;  Du Xiaoguang;  Xiao Shifu;  Wang Tao
收藏  |  浏览/下载:136/0  |  提交时间:2019/01/08


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