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科研机构
上海药物研究所 [5]
山东大学 [2]
江苏大学 [1]
中南大学 [1]
复旦大学上海医学院 [1]
上海生物化学与细胞生... [1]
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期刊论文 [12]
发表日期
2018 [12]
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A pectin from fruits of Lycium barbarum L. decreases Beta-amyloid peptide production through modulating APP processing
期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 201, 页码: 65-74
作者:
Zhou, Lishuang
;
Liao, Wenfeng
;
Zeng, Hui
;
Yao, Yanli
;
Chen, Xia
收藏
  |  
浏览/下载:153/0
  |  
提交时间:2019/01/08
Lycium barbarum L.
Pectin
A beta(42)
Alzheimer's disease
Amyloid precursor protein processing
Iron dysregulates APP processing accompanying with sAPP alpha cellular retention and beta-secretase inhibition in rat cortical neurons
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 2, 页码: 177-183
作者:
Chen, Yu-ting
;
Chen, Wu-yan
;
Huang, Xiao-tian
;
Xu, Ye-chun
;
Zhang, Hai-yan
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
iron
neurons
amyloid precursor protein
sAPP alpha
beta-amyloid
beta-secretase
Alzheimer's disease
Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2018, 卷号: 279
作者:
Wang, Pengzhen
;
Zheng, Xiaoyao
;
Guo, Qian
;
Yang, Peng
;
Pang, Xiaoying
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  |  
浏览/下载:50/0
  |  
提交时间:2019/12/05
Neuronal siRNA delivery
Blood-brain barrier (BBB)
beta-site amyloid precursor protein cleaving enzyme 1 (BACE1)
Cationic nanocomplexes
Alzheimer's disease
Live or let die: Neuroprotective and anti-cancer effects of nutraceutical antioxidants
期刊论文
Pharmacology and Therapeutics, 2018, 卷号: 183, 页码: 137-151
作者:
Mao, Xiao-Yuan*
;
Jin, Ming-Zhu
;
Chen, Jin-Fei*
;
Zhou, Hong-Hao
;
Jin, Wei-Lin*
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
PD
Parkinson's disease
AD
Alzheimer's disease
EGCG
(−)-Epigallocatechin-3-gallate
NRF2
NF-E2-related factor 2
ROS
reactive oxygen species
H2O2
hydrogen peroxide
ER
endoplasmic reticulum
GPX
glutathione-peroxidase
NOX
NADPH oxidases (NOXs)
LOX
lipoxygenases
ERK
extracellular signal-regulated kinase
JNK
c-Jun amino-terminal kinase
MAPK
mitogen-activated protein kinase
HNE
4-hydroxy-2-nonenol
ARE
antioxidant responsive element
GST
glutathione S-transferase
IFNγ
interferon-γ
LPS
lipopolysaccharide
SOD
superoxide dismutase
TNF-α
tumor necrosis factor-α
APP
β-amyloid precursor protein
SAM
S-adenosylmethionine
MAT
methionine adenosyltransferase
SAH
Sadenosyl homocysteine
MT
methyltransferases
BDNF
brain-derived neurotrophic factor
Nutraceuticals
Neuroprotection
Anti-cancer
ROS addiction
Ferroptosis
Oxidative stress
Visualization of Alzheimer's Disease Related alpha-/beta-/gamma-Secretase Ternary Complex by Bimolecular Fluorescence Complementation Based Fluorescence Resonance Energy Transfer
期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018, 卷号: 11, 期号: 1, 页码: 431
作者:
Wang, Xin
;
Pei, Gang
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  |  
浏览/下载:28/0
  |  
提交时间:2019/04/28
Amyloid Precursor Protein
Beta-secretase
App
Site
Cleavage
Adam10
Bace1
Localization
Dimerization
Endocytosis
Anti-inflammatory effects of bone marrow mesenchymal stem cells on mice with Alzheimer's disease
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2018, 卷号: 16, 期号: 6, 页码: 5015-5020
作者:
Wei, Yan
;
Xie, Zhaohong
;
Bi, Jianzhong
;
Zhu, Zhengyu
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
bone marrow mesenchymal stem cells
Alzheimer's disease
inflammatory
cytokines
amyloid precursor protein
presenilin-1 mouse
Amyloid precursor protein is overexpressed in bladder cancer and contributes to the malignant bladder cancer cell behaviors
期刊论文
INTERNATIONAL JOURNAL OF UROLOGY, 2018, 卷号: 25, 期号: 9, 页码: 808-816
作者:
Zhang, Dongqing
;
Zhou, Changkuo
;
Li, Yan
;
Gao, Lijian
;
Pang, Zhipeng
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
amyloid precursor protein
bladder cancer
cell cycle
cell
proliferation
extracellular signal-regulated protein kinases pathway
One-step synthesized flower-like materials used for sensitively detecting amyloid precursor protein
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2018, 卷号: 410, 期号: 26, 页码: 6901-6909
作者:
Wang, Chengke[1]
;
Tan, Rong[2]
;
Wang, Qingqing[3]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/24
Competitive immunoassay
Amyloid precursor protein
Alzheimer's disease
Poly-L-lysine
ELISA
Myelin injury in the central nervous system and Alzheimer's disease
期刊论文
Brain Research Bulletin, 2018, 卷号: 140, 页码: 162-168
作者:
Wang, Sha-Sha
;
Zhang, Zhao
;
Zhu, Tian-Bi
;
Chu, Shi-Feng
;
He, Wen-Bin
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/27
OLG
oligodendrocyte
CNS
central nervous system
SC
Schwann cell
PNS
peripheral nervous system
MBP
myelin basic protein
PLP
proteolipid protein
P0/MPZ
myelin protein zero
EAE
experimental allergic encephalomyelitis
MS
multiple sclerosis
CNP
2′ 3′-cyclic nucleotide 3′-phosphodiesterase
MAG
myelin associated glycoprotein
MOG
myelin oligodendrocyte glycoprotein
AD
Alzheimer's disease
OPC
oligodendrocyte precursor cell
NPC
neural progenitor cell
ROS
reactive oxygen species
TNF
tumour necrosis factor
AIF
apoptosis-inducing factor
IFN-γ
interferon gamma
ERK1/2
extracellular signal-regulated kinases-1 and -2
MAPK
mediators of mitogen-activated protein kinase
FGFR1/2
fibroblast growth factor receptors-1 and -2
Dock3
dedicator of cytokinesis 3
PERK
pancreatic endoplasmic reticulum kinase
GEF
guanine nucleotide exchange factor
SIRT2
sirtuin 2
NOD2
Nucleotide-binding oligomerization domain containing protein 2
RIPK2
receptor-interacting serine/threonine kinase 2
Shh
Sonic Hedgehog
NMO
neuromyelitis optica
ADEM
acute disseminated encephalomyelitis
ANHLE
acute necrotizing hemorrhagic leukoencephalitis
CPM
central pontine myelinolysis
Aβ
beta-amyloid
SP
senile plaque
NFT
neurofibrillary tangle
MRI
magnetic resonance imaging
Myelin
Oligodendrocyte
Demyelination
Neurodegenerative diseases
Alzheimer’s disease
Effect of microenvironment on beta-site amyloid precursor protein cleaving enzyme 1 expression in PC12 Cells
期刊论文
Journal of Shanghai Jiaotong University .Medical Science, 2018, 卷号: 38, 期号: 9, 页码: 1005-1012
作者:
Yang Huanqing
;
He Xiang
;
Du Xiaoguang
;
Xiao Shifu
;
Wang Tao
收藏
  |  
浏览/下载:136/0
  |  
提交时间:2019/01/08
Alzheimer's disease
microenvironment
PC12 cell
beta-site amyloid precursor protein cleaving enzyme 1 (BACE1)
amyloid-beta peptide (Abeta)
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