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科研机构
北京大学 [2]
中南大学 [2]
西安交通大学 [1]
吉林大学白求恩第一医... [1]
湖南中医药大学 [1]
内容类型
期刊论文 [7]
发表日期
2016 [7]
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Increased pulmonary arteriolar tone associated with lung oxidative stress and nitric oxide in a mouse model of Alzheimer's disease
期刊论文
PHYSIOLOGICAL REPORTS, 2016, 卷号: 4, 期号: 17
作者:
Roberts, Andrew M.
;
Jagadapillai, Rekha
;
Vaishnav, Radhika A.
;
Friedland, Robert P.
;
Drinovac, Robert
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/05
Amyloid precursor protein
endothelial dysfunction
lung microcirculation
neuroinflammation
reactive nitrogen species
Fluorescent turn-on determination of the activity of peptidases using peptide templated gold nanoclusters
期刊论文
Microchimica Acta, 2016, 卷号: 183, 期号: 2, 页码: 605-610
作者:
Luo, Junjun
;
Rasooly, Avraham
;
Wang, Liqiang
;
Zeng, Ke
;
Shen, Congcong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
beta-Secretases
APP cleaving enzyme
BACE1
beta-amyloid precursor protein
Transmission electron microscopy
Fluorometry
BACE1 in the retina: a sensitive biomarker for monitoring early pathological changes in Alzheimer's disease
期刊论文
Neural Regeneration Research, 2016, 卷号: 11, 期号: 3, 页码: 447-453
作者:
Lan Li
;
Jia Luo
;
Dan Chen
;
Jian-bin Tong
;
Le-ping Zeng
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
nerve
regeneration
neurodegenerative
disease
Alzheimer’s
disease
RETINA
amyloid-β
β-site
amyloid
precursor
protein
cleaving
enzyme
APP/PS-1
transgenic
mouse
neural
regeneration
nerve regeneration neurodegenerative disease Alzheimer's disease retina amyloid-β β-site amyloid precursor protein cleaving enzyme 1 APP/PS-1 transgenic mouse neural regeneration
Rosiglitazone ameliorates diffuse axonal injury by reducing loss of tau and up-regulating caveolin-1 expression
期刊论文
NEURAL REGENERATION RESEARCH, 2016, 卷号: 11, 期号: [db:dc_citation_issue], 页码: 944-950
作者:
Zhao, Yong-lin
;
Song, Jin-ning
;
Ma, Xu-dong
;
Zhang, Bin-fei
;
Li, Dan-dong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/02
cortex
immunocytochemistry
rats
neural regeneration
amyloid precursor protein
total tau
western blot assay
diffuse axonal injury
nerve regeneration
hyperphosphorylated tau
ser404
rosiglitazone
caveolin-1
Yeast Two-Hybrid Screening for Proteins that Interact with the Extracellular Domain of Amyloid Precursor Protein
期刊论文
NEUROSCIENCE BULLETIN, 2016
Yu, You
;
Li, Yinan
;
Zhang, Yan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/12/03
Amyloid precursor protein
Alzheimer&apos
Yeast two-hybrid screening
Cell death
Pelizaeus-Merzbacher disease
PELIZAEUS-MERZBACHER DISEASE
APP-BINDING
SURFACE
FLRT3
CELL
OUTGROWTH
ADHESION
NEURONS
SYSTEM
FE65
s disease
Primate-specific miR-603 is implicated in the risk and pathogenesis of Alzheimer's disease
期刊论文
AGING-US, 2016
Zhang, Chi
;
Lu, Jie
;
Liu, Bing
;
Cui, Qinghua
;
Wang, Yun
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/12/03
miR-603
single nucleotide polymorphism (SNP)
Alzheimer&apos
pathogenesis
biogenesis
RECEPTOR-RELATED PROTEIN
AMYLOID PRECURSOR PROTEIN
ALPHA-2-MACROGLOBULIN RECEPTOR
TAU-PHOSPHORYLATION
39-KDA PROTEIN
EXPRESSION
BRAIN
CLEARANCE
CELL
SUSCEPTIBILITY
s disease risk
The anti-dementia drug candidate, (-)-clausenamide, improves memory impairment through its multi-target effect
期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 162, 页码: 179-187
作者:
Chu, Shifeng
;
Liu, Shaolin
;
Duan, Wenzhen
;
Cheng, Yong
;
Jiang, Xueying
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
Chirality
Clausenamide
Dementia
Long-term potentiation
Signaling pathway
Calcium
6-OHDA
6-hydroxyldopamine
ACE
acetylcholinesterase
ACh
acetylcholine
AD
Alzheimer's disease
AUC0–12 h
0–12 h area under curve
APP
amyloid precursor protein
APV
R-2-amino-5-phosphonopentanoate
AUC0−∝
whole area under curve
BBB
blood–brain barrier
BDNF
brain-derived neurotrophic factor
CaM
calmodulin
CaMKII
calmodulin kinase II
ChAT
choline acetyltransferase
CREB
cAMP responding element binding
CHM
Chinese herbal medicine
clau
clausenamide
CL
clearance
Cmax
maximum concentration
CDK-5
cyclin-dependent kinase-5
DM
diabetes mellitus
DAG
diacylglycerol
ER
endoplasmic reticulum
ERK
extracellular signal-regulated kinases
GSK-3
glycogen synthase kinase-3
IP3
inositol triphosphate
LTP
long term potentiation
MWM
Morris water maze
NGF
nerve growth factor
NMDA
N-Methyl-D-aspartate
D
nNOS
neural nitric oxide synthase
PAT
passive avoidance tasks
Pir
piracetam
PLC
phospholipase C
PP1
phosphate 1
PKC
protein kinase C
tmax
time of peak concentration
t1/2α
absorption half-life
t1/2β
elimination half-life
Tau
microtubule-associated proteins
TCM
traditional Chinese medicine
Vd
apparent volume of distribution
VDCC
voltage-dependent calcium channel
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