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Discovery and development of pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 卷号: 110, 页码: 51-61
作者:
Li, Xin
;
Yang, Changyong
;
Wan, Hong
;
Zhang, Ge
;
Feng, Jun
收藏
  |  
浏览/下载:141/0
  |  
提交时间:2019/01/08
Pyrotinib
HER2-postive breast cancer
Irreversible EGFR/HER2 dual tyrosine kinase
inhibitor
Preclinical
Clinical
Safety
Drug metabolism
Serum Metabolic Profile Alteration Reveals Response to Platinum-Based Combination Chemotherapy for Lung Cancer: Sensitive Patients Distinguished from Insensitive ones
期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:
Xu, Shan
;
Zhou, Yanping
;
Geng, Hui
;
Song, Dandan
;
Tang, Jing
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2018/11/05
Genome-wide gene expression analysis in the amphioxus, Branchiostoma belcheri after poly (I: C) challenge using strand-specific RNA-seq
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 65, 页码: 108392-108405
作者:
Zhang, Qi-Lin
;
Xie, Zheng-Qing
;
Liang, Ming-Zhong
;
Luo, Bang
;
Wang, Xiu-Qiang
收藏
  |  
浏览/下载:116/0
  |  
提交时间:2019/05/22
Branchiostoma Belcheri
Transcriptome Analysis
Strand-specific Rna-seq
Poly (i:c)
Antiviral Immunity
Immunology
MKRMDA: multiple kernel learning-based Kronecker regularized least squares for MiRNA–disease association prediction
期刊论文
Journal of Translational Medicine, 2017, 卷号: 15, 期号: 1
作者:
Chen,Xing
;
Niu,Ya-Wei
;
Wang,Guang-Hui
;
Yan,Gui-Ying
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2018/07/30
miRNA
Disease
miRNA–disease association
Multiple kernel learning
Kronecker regularized least squares
MKRMDA: multiple kernel learning-based Kronecker regularized least squares for MiRNA-disease association prediction
期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2017, 卷号: 15, 页码: 14
作者:
Chen, Xing
;
Niu, Ya-Wei
;
Wang, Guang-Hui
;
Yan, Gui-Ying
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2018/07/30
miRNA
Disease
miRNA-disease association
Multiple kernel learning
Kronecker regularized least squares
Pyrrolidine Dithiocarbamate (PDTC) Attenuates Cancer Cachexia by Affecting Muscle Atrophy and Fat Lipolysis
期刊论文
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8
作者:
Miao, Chunxiao
;
Lv, Yuanyuan
;
Zhang, Wanli
;
Chai, Xiaoping
;
Feng, Lixing
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/01/08
cancer cachexia
PDTC
C2C12 myotubes
3T3-L1 adipocytes
muscle atrophy
fat lipolysis
Traceable Nanoparticles with Spatiotemporally Controlled Release Ability for Synergistic Glioblastoma Multiforme Treatment
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2017, 卷号: 27, 期号: 46, 页码: 1
作者:
Lu, Zhiguo
;
Li, Yan
;
Shi, Yuanjie
;
Li, Yanhui
;
Xiao, Zuobing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2018/01/19
Card-b6
Doxorubicin
Glioblastoma Multiforme
Spatiotemporally Controlled Release
Synergistic Treatment
Theranostic Prodrug Vesicles for Reactive Oxygen Species-Triggered Ultrafast Drug Release and Local-Regional Therapy of Metastatic Triple-Negative Breast Cancer
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2017, 卷号: 27, 期号: 46
作者:
Zhou, Fangyuan
;
Feng, Bing
;
Wang, Tingting
;
Wang, Dangge
;
Cui, Zhirui
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2019/01/08
cancer theranostics
local-regional therapy
prodrug vesicles
reactive oxygen species
triple-negative breast cancer
Hydrophilic Interaction Liquid Chromatography Coupled with Mass Spectrometry for Serum Metabolomics Analysis of Bladder Cancer
期刊论文
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2017, 卷号: 45, 期号: 12, 页码: 1921-1929
作者:
Zheng Si-Jia
;
Wang Qing-Qing
;
Wang Xiao-Lin
;
Zhao Xin-Jie
;
Xu Guo-Wang
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/06/20
Zwitterionic Hydrophilic Interaction Liquid Chromatography/mass Spectrometry
Metabolomics
Bladder Cancer
Polar Metabolites
Stainless Steel Hollow Microspheres for Arterial Embolization Hyperthermia
期刊论文
JOURNAL OF MEDICAL AND BIOLOGICAL ENGINEERING, 2017, 卷号: 37, 页码: 810-819
作者:
Wu, Jianan
;
Wang, Heng
;
Zhang, Han
;
Wei, Lanbin
;
Wang, Xiaowen
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2018/05/31
Stainless steel (SS)
Microscaled
Hollow
Microsphere
Magnetically induced hyperthermia (MIH)
Arterial embolization hyperthermia (AEH)
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