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科研机构
上海药物研究所 [3]
中国医学科学院 北京... [3]
北京大学 [2]
金属研究所 [1]
复旦大学上海医学院 [1]
内容类型
期刊论文 [9]
图书章节 [1]
发表日期
2016 [1]
2015 [4]
2014 [2]
2013 [3]
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A highly sensitive LC-MS/MS method for determination of ketoconazole in human plasma: Application to a clinical study of the exposure to ketoconazole in patients after topical administration
期刊论文
2016, 卷号: 128, 页码: 504-509
作者:
Wang, Keli
;
Wu, Yao
;
Chi, Zhiyan
;
Shu, Chang
;
Li, Lingjun
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/01/04
LC-MS/MS
Ketoconazole
Systemic exposure
Topical administration
Foam
Lotion
Pharmacodynamics and Pharmacokinetics of Fluticasone Furoate/Vilanterol in Healthy Chinese Subjects
期刊论文
2015, 卷号: 35, 期号: 6, 页码: 586-599
作者:
Chen, Xia
;
Zheng, Xin
;
Jiang, Ji
;
Hu, Pei
;
Wu, Kai
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/04
China
cortisol
fluticasone furoate
inhaled corticosteroids
long-acting beta(2) agonists
pharmacokinetics
pharmacodynamics
systemic exposure
vilanterol
Simultaneous determination of tazarotene and its active metabolite tazarotenic acid in minipig plasma by LC-MS/MS and its application in pharmacokinetic study after topical administration of tazarotene gel
期刊论文
2015, 卷号: 978, 页码: 173-178
作者:
Tong, Ying
;
Pan, Hong
;
Sun, Chenglong
;
Xin, Xiaofei
;
Ding, Li
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/13
Tazarotene
Tazarotenic acid
LC-MS/MS
Systemic exposure
Transdermal administration
Lipid-Based Formulations for Oral Drug Delivery: Effects on Drug Absorption and Metabolism
期刊论文
CURRENT DRUG METABOLISM, 2015, 卷号: 16, 期号: 3, 页码: 200-210
作者:
Zhu, Quanlei
;
Li, Xiuying
;
Xia, Dengning
;
Yu, Hongzhen
;
Chen, Dan
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Absorption
lipid formulations
metabolism
poorly soluble drug
systemic exposure
methylationanditsroleinthedispositionoftanshinolacardiovascularcarboxyliccatecholfromsalviamiltiorrhizarootsdanshen
期刊论文
actapharmacologicasinica, 2015, 卷号: 36, 期号: 5, 页码: 627
作者:
Tian Dandan
;
Jia Weiwei
;
Liu Xinwei
;
Wang Dandan
;
Liu Junhua
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
HERB-DRUG INTERACTIONS
O-METHYLTRANSFERASE
PLASMA HOMOCYSTEINE
PARKINSONS-DISEASE
CYTOSOLIC SULFOTRANSFERASE
ENDOTHELIAL DYSFUNCTION
MOLECULAR-MECHANISMS
DANHONG INJECTION
SYSTEMIC EXPOSURE
AQUEOUS EXTRACT
tanshinol
methylation
catechol-O-methyltransferase
herb-drug interaction
Salvia miltiorrhiza roots
Danshen
Proinflammatory Effects of Diesel Exhaust Nanoparticles on Scleroderma Skin Cells
期刊论文
Journal of Immunology Research, 2014
A. Mastrofrancesco
;
M. Alfe
;
E. Rosato
;
V. Gargiulo
;
C. Beatrice
;
G. Di Blasio
;
B. Zhang
;
D. S. Su
;
M. Picardo
;
S. Fiorito
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2015/01/14
systemic-sclerosis correlation
autoimmune-diseases
matrix
metalloproteinases
lupus-erythematosus
air-pollution
geoepidemiology
fibroblasts
mechanisms
expression
exposure
Titanium
图书章节
2014
作者:
Jin, Taiyi/55833644300[0]
;
Berlin, Maths/57191194495[1]
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/19
Absorption
Daily intake
Disposition
Dose-response relationships
Excretion
Local effects
Occupational exposure
Systemic effects
Systemic and cerebral exposure to and pharmacokinetics of flavonols and terpene lactones after dosing standardized Ginkgo biloba leaf extracts to rats via different routes of administration
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2013, 卷号: 170, 期号: 2, 页码: 440-457
作者:
Chen, Feng
;
Li, Li
;
Xu, Fang
;
Sun, Yan
;
Du, Feifei
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2019/01/08
Ginkgo biloba
GBE50
ShuXueNing injection
flavonols
terpene lactones
systemic exposure
cerebral exposure
pharmacokinetics
route of administration
PK markers
Beijing ambient particle exposure accelerates atherosclerosis in ApoE knockout mice
期刊论文
毒理学快报, 2013
Chen, Tian
;
Jia, Guang
;
Wei, Yongjie
;
Li, Jiucun
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/11
Ambient particle
Atherosclerosis
ApoE knockout mice
Systemic inflammation
Oxidative stress
Lipid metabolism
LOW-DENSITY-LIPOPROTEIN
MATTER AIR-POLLUTION
CORONARY-ARTERY-DISEASE
PARTICULATE MATTER
SUBCLINICAL ATHEROSCLEROSIS
CARDIOVASCULAR-DISEASE
OXIDIZED LDL
RESIDENTIAL EXPOSURE
PROGNOSTIC MARKER
OXIDATIVE STRESS
Increased cardiovascular risk due to systemic inflammatory changes and enhanced oxidative stress in urban Indian women
期刊论文
air quality atmosphere and health, 2013
Dutta, Anindita
;
Ray, Manas Ranjan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/10
Ambient air pollution
Systemic inflammation
Oxidative stress
Hypertension
Urban women
India
PARTICULATE AIR-POLLUTION
AMERICAN-HEART-ASSOCIATION
HEALTH-CARE PROFESSIONALS
ULTRAFINE PARTICLES
BLOOD-PRESSURE
TERM EXPOSURE
DISEASE
HYPERTENSION
STATEMENT
POPULATION
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