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厦门大学 [1]
北京大学 [1]
上海药物研究所 [1]
水生生物研究所 [1]
昆明植物研究所 [1]
中国科学院大学 [1]
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期刊论文 [8]
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2021 [1]
2018 [1]
2017 [1]
2013 [2]
2012 [1]
2007 [2]
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Virology [1]
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Synthesis and Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitory Activity Evaluation of Novel Arylaminoacetylhydrazone Derivatives Containing Carbazole Moiety
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3157-3170
作者:
Li Yingjun
;
Lin Ledi
;
Jin Kun
;
Gao Lixin
;
Sheng Li
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/11/04
protein tyrosine phosphatase 1B (PTP1B) inhibitor
carbazole
arylaminoacetylhydrazone
synthesis
molecular docking
The plant sesquiterpene lactone parthenolide inhibits Wnt/-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 14, 页码: 5335-5344
作者:
Zhu, Xiaoliang
;
Yuan, Chunmao
;
Tian, Chenyang
;
Li, Chen
;
Nie, Fen
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  |  
浏览/下载:45/0
  |  
提交时间:2018/05/08
Inhibitor
Protein Synthesis
Small Molecule
T-cell Factor (Tcf)
Wnt Signaling
Biosynthesis of the pyrrolidine protein synthesis inhibitor anisomycin involves novel gene ensemble and cryptic biosynthetic steps
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 卷号: 114, 期号: 16
作者:
Zheng, Xiaoqing
;
Cheng, Qiuxiang
;
Yao, Fen
;
Wang, Xiaozheng
;
Kong, Lingxin
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  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
pyrrolidine antibiotics
anisomycin biosynthetic pathway
protein synthesis inhibitor
cryptic glycosylation
Streptomyces
Synthesis and biological characterization of synthetic analogs of Huwentoxin-IV (Mu-theraphotoxin-Hh2a), a neuronal tetrodotoxin-sensitive sodium channel inhibitor
期刊论文
Toxicon, 2013, 卷号: 71, 页码: 57-65
作者:
Deng, Meichun*
;
Luo, Xuan
;
Jiang, Liping
;
Chen, Hanchun
;
Wang, Jun
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/03
DRG
Dorsal root ganglion
HPLC
HWTX
HWTX-IV
High pressure liquid chromatography
Huwentoxin
IC(50)
ICK
Inhibitor cystine knot
Kv channel
MALDI-TOF
Matrix assisted laser desorption/ionization time-of-flight
Median inhibitory concentration
Mutant
Patch-clamp
Protein folding
Solid-phase peptide synthesis
TTX
TTX-R
TTX-S
TTX-resistant
TTX-sensitive
Tetrodotoxin
VGSC
Voltage-gated potassium channel
Voltage-gated sodium channel
Synthesis and screening of 3-MA derivatives for autophagy inhibitors
期刊论文
autophagy, 2013
Wu, Yanyang
;
Wang, Xin
;
Guo, Haijing
;
Zhang, Bo
;
Zhang, Xiao-Bo
;
Shi, Zhang-Jie
;
Yu, Li
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  |  
浏览/下载:5/0
  |  
提交时间:2015/11/11
autophagy
inhibitor
3-MA
synthesis
derivatives
ISOLATED RAT HEPATOCYTES
PROTEIN-KINASE-B
PHOSPHATIDYLINOSITOL 3-KINASE
3-METHYLADENINE
DEGRADATION
WORTMANNIN
LY294002
AKT
Requirement of the phosphatidylinositol 3-kinase/Akt signaling pathway for the effect of nicotine on interleukin-1beta-induced chondrocyte apoptosis in a rat model of osteoarthritis
期刊论文
http://dx.doi.org/10.1016/j.bbrc.2012.06.045, 2012
Zheng, Xinpeng
;
Xia, Chun
;
Chen, Zhongyi
;
Huang, Jiagu
;
Gao, Fengguang
;
Li, Guideng
;
Zhang, Bing
;
夏春
;
高丰光
;
张兵
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  |  
浏览/下载:5/0
  |  
提交时间:2015/07/22
MATRIX METALLOPROTEINASE-13 EXPRESSION
ARTICULAR CHONDROCYTES
PROTEIN-KINASE
PROTEOGLYCAN SYNTHESIS
CELL-DEATH
CARTILAGE
ACTIVATION
GROWTH
PHOSPHORYLATION
INHIBITOR
Synthesis and preliminary cytotoxic evaluation of substituted indoles as potential anticancer agents
期刊论文
Chinese chemical letters, 2007, 卷号: 18, 期号: 8, 页码: 899-901
作者:
Shi, Chang Qing
;
Liu, Zhang Qin
;
Lin, Wen Qing
;
Chen, Yuan Wei
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/05/10
Indoles
Synthesis
Kinesin spindle protein inhibitor
Cytotoxicity
Cancer treatment
Characterization of an early gene encoding for dUTPase in Rana grylio virus
期刊论文
VIRUS RESEARCH, 2007, 卷号: 123, 期号: 2, 页码: 128-137
作者:
Zhao, Zhe
;
Ke, Fei
;
Gui, Jianfang
;
Zhang, Qiya
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2010/10/13
Rana grylio virus (RGV)
iridovirus
DUTPase (DUT)
early viral gene
protein synthesis inhibitor
DNA replication inhibitor
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