QQ客服 官方微博 反馈留言

	Synthesis and preliminary cytotoxic evaluation of substituted indoles as potential anticancer agents
	Shi, Chang Qing; Liu, Zhang Qin; Lin, Wen Qing; Chen, Yuan Wei
刊名	Chinese chemical letters
	2007-08-01
卷号	18期号:8页码:899-901
关键词	Indoles Synthesis Kinesin spindle protein inhibitor Cytotoxicity Cancer treatment
ISSN号	1001-8417
DOI	10.1016/j.cclet.2007.05.052
通讯作者	Chen, yuan wei(chenyw@cioc.ac.en)
英文摘要	A variety of indole derivatives were designed, synthesized and preliminarily evaluated for their in vitro cytotoxic activity in the a431 and h460 cell lines. all the compounds examined conferred unusual potency in a tumor cell cytotoxicity assay. the findings showed the indole derivatives would be a promising candidate for the development of new anticancer agents. (c) 2007 yuan wei chen. published by elsevier b.v. on behalf of chinese chemical society. all rights reserved.
WOS关键词	SPINDLE PROTEIN KSP ; MITOTIC KINESIN EG5 ; INHIBITORS ; DISCOVERY ; MOTORS
WOS研究方向	Chemistry
WOS类目	Chemistry, Multidisciplinary
语种	英语
出版者	CHINESE CHEMICAL SOC
WOS记录号	WOS:000248994600002
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2380102
专题	中国科学院大学
通讯作者	Chen, Yuan Wei
作者单位	1.Chinese Acad Sci, Chengdu Inst Organ Chem, Key Lab Asymmetr Synth & Chirotechnol Sichuan Pro, Chengdu 610041, Peoples R China 2.Chinese Acad Sci, Chengdu Inst Organ Chem, Union Lab Asymmetr Synth, Chengdu 610041, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Shi, Chang Qing,Liu, Zhang Qin,Lin, Wen Qing,et al. Synthesis and preliminary cytotoxic evaluation of substituted indoles as potential anticancer agents[J]. Chinese chemical letters,2007,18(8):899-901.
APA	Shi, Chang Qing,Liu, Zhang Qin,Lin, Wen Qing,&Chen, Yuan Wei.(2007).Synthesis and preliminary cytotoxic evaluation of substituted indoles as potential anticancer agents.Chinese chemical letters,18(8),899-901.
MLA	Shi, Chang Qing,et al."Synthesis and preliminary cytotoxic evaluation of substituted indoles as potential anticancer agents".Chinese chemical letters 18.8(2007):899-901.

个性服务

查看访问统计

相关权益政策

暂无数据

收藏/分享

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。