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CORC

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Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance 期刊论文
European Journal of Medicinal Chemistry, 2017, 卷号: 135, 页码: 34-48
作者:  Zha, Gao-Feng;  Qin, Hua-Li*;  Youssif, Bahaa G. M.;  Amjad, Muhammad Wahab;  Raja, Maria Abdul Ghafoor
收藏  |  浏览/下载：14/0  |  提交时间：2019/12/04
Epidermal growth factor receptor (EGFR)  BRAF  Focal adhesion kinase (FAK)  Tubulin polymerization  Cancer cell lines  MDR  multidrug resistance  EGFR  epidermal growth factor receptor  EMEA  European Medicines Evaluation Agency  FDA  US Food and Drug Administration  NSCLC  non-small cell lung  FAK  focal adhesion kinase  RTK  receptor tyrosine kinases  MAPK  mitogen-activated protein kinase  ABC  ATP-binding cassette  NF-kB  NF-kappaB  FERM  Four-point-one, ezrin, radixin, moesin  TMP  Ligustrazine or tetramethylpyrazine  Adr  Adriamycin  DRS  death receptors  TFN  tumor necrosis factor  PI  propidium iodide  TKIs  tyrosine kinase inhibitors  FAR  fluorescence activity ratio  HRMS  high resolution mass spectra  TLC  thin layer chromatography  UV  ultraviolet  DMEM  Dulbecco's modified Eagle's medium  DMSO  dimethyl sulfoxide  IBX  2-iodoxybenzoic acid  
Cytotoxicity and apoptosis induced by mixed mycotoxins (T-2 and HT-2 toxin) on primary hepatocytes of broilers in vitro 期刊论文
Toxicon, 2017, 卷号: 129, 页码: 1-10
作者:  Yang, Lingchen*;  Tu, Di;  Zhao, Zhiyong;  Cui, Jun
收藏  |  浏览/下载：6/0  |  提交时间：2019/12/23
Apolipoprotein mediates soft-shelled turtle systemic septicemia spherical virus (STSSSV) infection 期刊论文
Aquaculture, 2017, 卷号: 473, 页码: 501-507
作者:  Chen, Meijuan;  Li, Dengfeng*;  Fang, Jing;  Zhang, Liping;  Gu, Yehua
收藏  |  浏览/下载：14/0  |  提交时间：2019/12/23
STSSSV  soft-shelled turtle systemic septicemia spherical virus  PApoB  Pelodiscus sinensis apolipoprotein B  ApoB  apolipoprotein B  STSS  soft-shelled turtle systemic septicemia  Ab  antibody  VOPBA  viral overlay protein binding assay  PBS  phosphate buffered saline  ELISA  enzyme linked immunosorbent assay  PMSF  phenylmethylsulfonyl fluoride  EDTA  ethylenediaminetetraacetic acid  NP-40  Nonidet P-40  NETN  Tris-EDTA-buffered saline with NP-40  MS  Mass spectrometry  MALDI-TOF-MS  matrix-assisted laser desorption/ionization time-of-flight mass spectrometry  IgG  Immunoglobulin G  FITC  fluorescein isothiocyanate  TRITC  tetraethyl rhodamine isothiocyanate  SDS-PAGE  sodium dodecylsulfate-polyacrylamide gel electrophoresis  DAPI  4′,6-diamidino-2-phenylindole  PI  propidium iodide  VLDL  very low density lipoprotein  LDL  low density lipoprotein  LDL-R  low density lipoprotein receptor  ER  endoplasmic reticulum  VSV  vesicular stomatitis virus  HCV  hepatitis C virus  BVDV  Bovine viral diarrhea virus  HGV  GB virus C/hepatitis G virus  STSSSV  Pelodiscus sinensis  Apolipoprotein B  VOPBA  Co-immunoprecipitation  
Exopolysaccharide from Trichoderma pseudokoningii induces the apoptosis of MCF-7 cells through an intrinsic mitochondrial pathway 期刊论文
Carbohydrate Polymers, 2016, 卷号: 136, 页码: 1065-1073
作者:  Wang, Guodong;  Liu, Chunyan;  Liu, Jun;  Liu, Bo;  Li, Ping
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/03
Alternation of adriamycin penetration kinetics in MCF-7 cells from 2D to 3D culture based on P-gp expression through the Chk2/p53/NF-κB pathway 期刊论文
Biochemical Pharmacology, 2015, 卷号: 93, 期号: 2, 页码: 210-220
作者:  Lu, Meng;  Zhou, Fang;  Hao, Kun;  Liu, Jiali;  Chen, Qianying
收藏  |  浏览/下载：16/0  |  提交时间：2019/12/03
Adriamycin (PubChem CID: 31703)  LY335979 (PubChem CID: 153997)  AZD7762 (PubChem CID: 11152667)  Nutlin-3 (PubChem CID: 216345)  DMSO (PubChem CID: 679)  Propidium iodide (PubChem CID: 104981)  MTT formazan (PubChem CID: 16218671)  ADR  adriamycin  AUC  area under the concentration–time curve  ECM  extracellular matrix  ESI  electrospray ionization  HBSS  Hank's balanced salt solution  LC–MS/MS  liquid chromatography tandem mass spectrometry  MCL  multi-cellular layer  MCR  multi-cellular resistance  MCS  multi-cellular spheroid  MDR  multi-drug resistance  MRM  multiple reaction monitoring  P-gp  P-glycoprotein  PI  propidium iodide  qPCR  quantitative real-time PCR  S.E.  standard error  Multi-cellular layer  Penetration kinetics  P-gp  Chk2/p53/NF-κB pathway  
Downregulation of miR-363 increases drug resistance in cisplatin-treated HepG2 by dysregulating Mcl-1 期刊论文
Gene, 2015, 卷号: 572, 期号: 1, 页码: 116-122
作者:  Ou, Yangyang;  Zhai, Denggao;  Wu, Nan;  Li, Xiaoli*
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/03
DNA binding, cytotoxicity and apoptosis induction activity of a mixed-ligand copper(II) complex with taurine Schiff base and imidazole 期刊论文
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2014, 卷号: 128, 页码: 686-693
作者:  Li, Mei;  Kong, Lin Lin;  Gou, Yi;  Yang, Feng*;  Liang, Hong
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/03
Synthesis, characterization and anti-proliferative activity of heterocyclic hypervalent organoantimony compounds 期刊论文
European Journal of Medicinal Chemistry, 2014, 卷号: 79, 页码: 391-398
作者:  Chen, Yi;  Yu, Kun;  Tan, Nian-Yuan;  Qiu, Ren-Hua;  Liu, Wei
收藏  |  浏览/下载：16/0  |  提交时间：2019/12/03
Synthesis, characterization and anti-proliferative activity of heterocyclic hypervalent organoantimony compounds 期刊论文
European Journal of Medicinal Chemistry, 2014, 卷号: 79, 页码: 391-398
作者:  Chen, Yi（陈懿）;  Yu, Kun;  Tan, Nian-Yuan;  Qiu, Ren-Hua;  Liu, Wei
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/27
H. pylori-encoded CagA disrupts tight junctions and induces invasiveness of AGS gastric carcinoma cells via Cdx2-dependent targeting of Claudin-2 期刊论文
Cellular Immunology, 2013, 卷号: 286, 期号: 1-2, 页码: 22-30
作者:  Song, Xin;  Chen, Hui-Xin;  Wang, Xiao-Yan;  Deng, Xi-Yun;  Xi, Yin-Xue
收藏  |  浏览/下载：12/0  |  提交时间：2019/12/03

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