CORC

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CORC

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Bexarotent attenuated CCI-induced spinal neuroinflammation and neuropathic pain by targeting MKP-1. 期刊论文
The journal of pain : official journal of the American Pain Society, 2019
作者:  Gui, Yulong;  Duan, Shunyuan;  Xiao, Lihong;  Tang, Jing;  Li, Aiyuan*
收藏  |  浏览/下载：20/0  |  提交时间：2019/12/27
Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy 期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 4, 页码: 552-562
作者:  Liu, Feifei;  Yang, Xiaotong;  Geng, Meiyu;  Huang, Min
收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08
RLCKs Bridge Plant Immune Receptors and MAPK Cascades 期刊论文
TRENDS IN PLANT SCIENCE, 2018, 卷号: 23, 期号: 12, 页码: 1039-1041
作者:  Cui, Fuhao;  Sun, Wenxian;  Kong, Xiangpei
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/11
Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways 期刊论文
2018, 卷号: 99, 页码: 115-123
作者:  Shao, Qian-hang;  Zhang, Xiao-ling;  Chen, Ying;  Zhu, Cheng-Gen;  Shi, Jian-Gong
收藏  |  浏览/下载：4/0  |  提交时间：2020/01/03
The Application Methods of Mitogen-activated Protein Kinase Signal Pathway Inhibitors SP600125 and SB203580 in Long-term in Vivo Experiments 期刊论文
WEST INDIAN MEDICAL JOURNAL, 2018, 卷号: 67, 期号: 2, 页码: 98-104
作者:  Cai, H.;  Chen, Q.*;  Liu, Y.;  Xie, H.;  Lu, Q.
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/27
Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways 期刊论文
Molecular Immunology, 2018, 卷号: 99, 页码: 115-123
作者:  Shao, Qian-hang;  Zhang, Xiao-ling;  Chen, Ying;  Zhu, Cheng-Gen;  Shi, Jian-Gong
收藏  |  浏览/下载：14/0  |  提交时间：2019/12/27
Myelin injury in the central nervous system and Alzheimer's disease 期刊论文
Brain Research Bulletin, 2018, 卷号: 140, 页码: 162-168
作者:  Wang, Sha-Sha;  Zhang, Zhao;  Zhu, Tian-Bi;  Chu, Shi-Feng;  He, Wen-Bin
收藏  |  浏览/下载：28/0  |  提交时间：2019/12/27
OLG  oligodendrocyte  CNS  central nervous system  SC  Schwann cell  PNS  peripheral nervous system  MBP  myelin basic protein  PLP  proteolipid protein  P0/MPZ  myelin protein zero  EAE  experimental allergic encephalomyelitis  MS  multiple sclerosis  CNP  2′ 3′-cyclic nucleotide 3′-phosphodiesterase  MAG  myelin associated glycoprotein  MOG  myelin oligodendrocyte glycoprotein  AD  Alzheimer's disease  OPC  oligodendrocyte precursor cell  NPC  neural progenitor cell  ROS  reactive oxygen species  TNF  tumour necrosis factor  AIF  apoptosis-inducing factor  IFN-γ  interferon gamma  ERK1/2  extracellular signal-regulated kinases-1 and -2  MAPK  mediators of mitogen-activated protein kinase  FGFR1/2  fibroblast growth factor receptors-1 and -2  Dock3  dedicator of cytokinesis 3  PERK  pancreatic endoplasmic reticulum kinase  GEF  guanine nucleotide exchange factor  SIRT2  sirtuin 2  NOD2  Nucleotide-binding oligomerization domain containing protein 2  RIPK2  receptor-interacting serine/threonine kinase 2  Shh  Sonic Hedgehog  NMO  neuromyelitis optica  ADEM  acute disseminated encephalomyelitis  ANHLE  acute necrotizing hemorrhagic leukoencephalitis  CPM  central pontine myelinolysis  Aβ  beta-amyloid  SP  senile plaque  NFT  neurofibrillary tangle  MRI  magnetic resonance imaging  Myelin  Oligodendrocyte  Demyelination  Neurodegenerative diseases  Alzheimer’s disease  
Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways 期刊论文
Molecular immunology, 2018, 卷号: 99, 页码: 115-123
作者:  Shao, Qian-hang;  Zhang, Xiao-ling;  Chen, Ying;  Zhu, Cheng-Gen;  Shi, Jian-Gong
收藏  |  浏览/下载：6/0  |  提交时间：2019/12/27
targetingerkanachillesheelofthemapkpathwayincancertherapy 期刊论文
actapharmaceuticasinicab, 2018, 卷号: 8, 期号: 4, 页码: 552
作者:  Liu Feifei;  Yang Xiaotong;  Geng Meiyu;  Huang Min
收藏  |  浏览/下载：4/0  |  提交时间：2020/07/01
Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance 期刊论文
European Journal of Medicinal Chemistry, 2017, 卷号: 135, 页码: 34-48
作者:  Zha, Gao-Feng;  Qin, Hua-Li*;  Youssif, Bahaa G. M.;  Amjad, Muhammad Wahab;  Raja, Maria Abdul Ghafoor
收藏  |  浏览/下载：14/0  |  提交时间：2019/12/04
Epidermal growth factor receptor (EGFR)  BRAF  Focal adhesion kinase (FAK)  Tubulin polymerization  Cancer cell lines  MDR  multidrug resistance  EGFR  epidermal growth factor receptor  EMEA  European Medicines Evaluation Agency  FDA  US Food and Drug Administration  NSCLC  non-small cell lung  FAK  focal adhesion kinase  RTK  receptor tyrosine kinases  MAPK  mitogen-activated protein kinase  ABC  ATP-binding cassette  NF-kB  NF-kappaB  FERM  Four-point-one, ezrin, radixin, moesin  TMP  Ligustrazine or tetramethylpyrazine  Adr  Adriamycin  DRS  death receptors  TFN  tumor necrosis factor  PI  propidium iodide  TKIs  tyrosine kinase inhibitors  FAR  fluorescence activity ratio  HRMS  high resolution mass spectra  TLC  thin layer chromatography  UV  ultraviolet  DMEM  Dulbecco's modified Eagle's medium  DMSO  dimethyl sulfoxide  IBX  2-iodoxybenzoic acid  

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