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科研机构
中国医学科学院 北京... [3]
四川大学 [2]
复旦大学上海医学院 [2]
上海药物研究所 [1]
吉林大学白求恩第一医... [1]
湖南大学 [1]
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期刊论文 [10]
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2015 [1]
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2013 [2]
2010 [2]
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浏览/检索结果:
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The effect of PLGA-based hydrogel scaffold for improving the drug maximum-tolerated dose for in situ osteosarcoma treatment
期刊论文
COLLOIDS AND SURFACES B-BIOINTERFACES, 2018, 卷号: 172
作者:
Liu, Jianguo
;
Chen, Xuesi
;
Zang, Junting
;
Gong, Yubao
;
Li, Dongsong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Injectable hydrogel
Maximum tolerated dose
Localized drug delivery
Cancer therapy
淋巴结阳性食管癌术后预防性IMRT同期化疗的临床Ⅰ期研究
期刊论文
2016, 卷号: 25, 期号: 1, 页码: 26-31
作者:
于舒飞
;
章文成
;
王奇峰
;
肖泽芬
;
周宗玫
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/01/04
食管肿瘤/外科学 食管肿瘤/放射疗法 食管肿瘤/化学疗法 最大耐受剂量 剂量限制性毒性 Esophageal neoplasms/surgery Esophageal neoplasms/radiotherapy Esophageal neoplasms/chemoradiation Maximum-tolerated dose Dose-limiting toxicity
Endostar in combination with modified FOLFOX6 as an initial therapy in advanced colorectal cancer patients: a phase I clinical trial
期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2015, 卷号: 75, 期号: 3
作者:
Chen, Zhiyu
;
Guo, Weijian
;
Cao, Junning
;
Lv, Fangfang
;
Zhang, Wen
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/19
RhEndostatin
Combination chemotherapy
Colorectal cancer
Modified FOLFOX6
Dose-limiting toxicity
Maximum tolerated dose
Phase I and pharmacokinetic study of polymeric micelle-formulated paclitaxel in adult Chinese patients with advanced solid tumors
期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2014, 卷号: 73, 期号: 6
作者:
Lv, Fangfang
;
Cao, Junning
;
Zhang, Jian
;
Qian, Jun
;
Peng, Wei
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/19
Drug toxicity
Maximum tolerated dose
Micelles
Paclitaxel
Pharmacokinetics
Polymers
Dose-finding study on adjuvant chemotherapy with S-1 plus oxaliplatin for gastric cancer
期刊论文
2014, 卷号: 2, 期号: 1, 页码: 93-98
作者:
Yang Lin
;
Yang Yi
;
Qin Qiong
;
Zhou Aiping
;
Zhao Jianjun
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/13
S-1
adjuvant chemotherapy
cytochrome P450 2A6
maximum-tolerated dose
oxaliplatin
Phase I study of postoperative radiotherapy combined with capecitabine for gastric cancer
期刊论文
2014, 卷号: 20, 期号: 4, 页码: 1067-1073
作者:
Wang, Xin
;
Jin, Jing
;
Li, Ye-Xiong
;
Ren, Hua
;
Fang, Hui
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/13
Radiotherapy
Capecitabine
Gastric cancer
Maximum tolerated dose
Dose-limiting toxicity
Dose-Effect Relationship in the Toxicity Qualitative Response of Strychni Semen Ultrafine Powder
期刊论文
Journal of Traditional Chinese Medicine, 2013, 卷号: Vol.54 No.11, 页码: 958-960,982
作者:
Wang Yuhong
;
Yang Hui
;
Mo Weihao
;
Yang Ying
;
Zhang Xiuli
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/05
strychni semen ultrafine powder
median lethal dose
minimum lethal dose
maximum tolerated dose
Reflections on the Bridging Methods in the Early Exploratory General Toxicology Study
期刊论文
Chinese Pharmaceutical Journal, 2013, 卷号: 48, 期号: 21, 页码: 1785-1788
作者:
Liu Yongzhen
;
Gong Likun
;
Ren Jin
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
acute toxicity study
maximum tolerated dose
dose range finding study
Postoperative chemoradiotherapy in gastric cancer: a phase I study of radiotherapy with dose escalation of oxaliplatin, 5-fluorouracil, and leucovorin (FOLFOX regimen)
期刊论文
International Organizations Law Review, 2010
-
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/03/05
Adult
Antineoplastic
Combined
Chemotherapy
Protocols/*administration
&
dosage/adverse
effects
Chemoradiotherapy/adverse
effects/*methods
Dose-Response
Relationship,
Drug
Drug-Induced
Liver
Injury/etiology
Female
Fluorouracil/administration
&
dosage/adverse
effects
Gastrectomy
Humans
Leucovorin/administration
&
dosage/adverse
effects
Male
Maximum
Tolerated
Dose
Middle
Aged
Organoplatinum
Compounds/administration
&
dosage/adverse
effects
Stomach
Neoplasms/pathology/surgery/*therapy
Design, Synthesis and Biological Evaluation of Lipophilic Analogs of Anethol Trithione
期刊论文
Letters in Drug Design & Discovery, 2010, 卷号: Vol.7 No.10, 页码: 747-753
作者:
Xiao-Cen Li
;
Wei Fan
;
Li Hai
;
Shan Qian
;
Qui-Qi Xiao and Mei Guan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/03/26
Synthesis
Anethol
trithione
Lipophilicity
Bioavailability
Prodrugs
ATT
glutamyl
cysteine
synthetase
glutathione
GSH
IR
HNMR
ESI-MS
pyridine
hydrochloride
HPLC
alanine
transaminases
aspartate
transaminases
AST
Acute
Toxicity
Test
maximum
tolerated
dose
YRT-3
melting
point
apparatus
IR
spectra
Perkin-Elmer983
NMR
spectra
INOVA400
Bruker
AC-E200
Agilent
1946B
ESI-MS
instrument
5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione
4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl
acetate
4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl
propionate
(E)-4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl
but-2-enoate
4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl
isobutyrate
4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl
benzoate
4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl
2-phenylacetate
4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl
stearate
4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl
pivalate
4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl
cinnamate
4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl
2-fluorobenzoate
4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl
4-chlorobenzoate
4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl
3-phenylpropanoate
4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl
3,3-diphenylpropan-oate
(3-thioxo-3H-1,2-dithiol-5-yl)phenyl
1,2,3,4-tetrahydro-naphthalene-1-carboxylate
(3o)
4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl
5,6,7,8-tetrahydro-naphthalene-1-carboxylate
SPD-10A
variable
UV-VIS
detector
ODS
column
ICR
mice
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