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	Design, Synthesis and Biological Evaluation of Lipophilic Analogs of Anethol Trithione
	Xiao-Cen Li; Wei Fan; Li Hai; Shan Qian; Qui-Qi Xiao and Mei Guan
刊名	Letters in Drug Design & Discovery
	2010
卷号	Vol.7 No.10页码:747-753
关键词	Synthesis Anethol trithione Lipophilicity Bioavailability Prodrugs ATT glutamyl cysteine synthetase glutathione GSH IR HNMR ESI-MS pyridine hydrochloride HPLC alanine transaminases aspartate transaminases AST Acute Toxicity Test maximum tolerated dose YRT-3 melting point apparatus IR spectra Perkin-Elmer983 NMR spectra INOVA400 Bruker AC-E200 Agilent 1946B ESI-MS instrument 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione 4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl acetate 4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl propionate (E)-4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl but-2-enoate 4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl isobutyrate 4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl benzoate 4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl 2-phenylacetate 4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl stearate 4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl pivalate 4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl cinnamate 4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl 2-fluorobenzoate 4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl 4-chlorobenzoate 4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl 3-phenylpropanoate 4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl 3,3-diphenylpropan-oate (3-thioxo-3H-1,2-dithiol-5-yl)phenyl 1,2,3,4-tetrahydro-naphthalene-1-carboxylate (3o) 4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl 5,6,7,8-tetrahydro-naphthalene-1-carboxylate SPD-10A variable UV-VIS detector ODS column ICR mice
ISSN号	1570-1808
URL标识	查看原文
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/1997124
专题	四川大学
作者单位	West China Hospital, Sichuan University, No. 37, GuoXue road, Chengdu, Sichuan 610041, P.R. China.
推荐引用方式 GB/T 7714	Xiao-Cen Li,Wei Fan,Li Hai,et al. Design, Synthesis and Biological Evaluation of Lipophilic Analogs of Anethol Trithione[J]. Letters in Drug Design & Discovery,2010,Vol.7 No.10:747-753.
APA	Xiao-Cen Li,Wei Fan,Li Hai,Shan Qian,&Qui-Qi Xiao and Mei Guan.(2010).Design, Synthesis and Biological Evaluation of Lipophilic Analogs of Anethol Trithione.Letters in Drug Design & Discovery,Vol.7 No.10,747-753.
MLA	Xiao-Cen Li,et al."Design, Synthesis and Biological Evaluation of Lipophilic Analogs of Anethol Trithione".Letters in Drug Design & Discovery Vol.7 No.10(2010):747-753.

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