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浏览/检索结果:
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Oligomannuronate prevents mitochondrial dysfunction induced by IAPP in RINm5F islet cells by inhibition of JNK activation and cell apoptosis
期刊论文
Chinese Medicine, 2020, 卷号: 15, 期号: 1, 页码: 1-12.
作者:
Xi Liu
;
Qiong Li
;
Xiaolei Cheng
;
Zhichun Liu
;
Xiaoliang Zhao
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/03/10
Oligomannuronate
Type 2 diabetes
Islet amyloid polypeptide
JNK activation
Mitochondrial dysfunction
RINm5F cells
All-atom structure ensembles of islet amyloid polypeptides determined by enhanced sampling and experiment data restraints
期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2019, 卷号: 87, 期号: 7, 页码: 541-550
作者:
Su, Xinyue
;
Wang, Ke
;
Liu, Na
;
Chen, Jiawen
;
Li, Yong
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2019/10/14
aggregation
chemical shift restraint
islet amylod polypeptide
metadynamics
CLINICAL STUDY ON THE TREATMENT OF ISLET B CELL FAILURE TYPE 2 DIABETES WITH INSULIN LYSINE COMBINED WITH INSULIN GLULISINE
期刊论文
ACTA MEDICA MEDITERRANEA, 2019, 卷号: 35, 期号: 4
作者:
Liu, Shufang
;
Kong, Fanling
;
Wang, Yi
;
Zhang, Xiaoyong
;
Gao, Xiaoli
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/05
Insulin glulisine
insulin glargine
islet beta cell failure type 2 diabetes
Aldosterone induced up-expression of ICAM-1 and ET-1 in pancreatic islet endothelium may associate with progression of T2D
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 512, 期号: 4, 页码: 750-757
作者:
Wang, Jinbang
;
Hu, Huiqing
;
Song, Jia
;
Yan, Fei
;
Qin, Jun
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/11
Aldosterone
Islet endothelium
ICAM-1
Endothelin-1
MicroRNA-21 silencing prolongs islet allograft survival by inhibiting Th17 cells
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2019, 卷号: 66, 页码: 274-281
作者:
Wang, Hui[1]
;
Fan, Huimin[2]
;
Tao, Jialing[3]
;
Shao, Qixiang[4]
;
Ding, Qing[5]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/24
Islet transplantation
MicroRNA-21
Th17 cells
IL-10-expressing regulatory B cells (Bregs B10)
Opposing effects of IL-1β/COX-2/PGE2 pathway loop on islets in type 2 diabetes mellitus
期刊论文
2019, 卷号: 66, 期号: 8, 页码: 691-699
作者:
Wang Guanqiao
;
Liang Rui
;
Liu Tengli
;
Wang Le
;
Zou Jiaqi
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/01/03
COX-2
IL-1β
Inflammation
Islet dysfunction
Type 2 diabetes mellitus
The Inhibitory Effect of Hydroxylated Carbon Nanotubes on the Aggregation of Human Islet Amyloid Polypeptide Revealed by a Combined Computational and Experimental Study
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 11
作者:
Mo, Yuxiang
;
Brahmachari, Sayanti
;
Lei, Jiangtao
;
Gilead, Sharon
;
Tang, Yiming
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
protein aggregation
human islet amyloid polypeptide
hydroxylated carbon nanotubes
inhibitory mechanism
replica exchange molecular dynamics simulations
TEM experiment
Replica Exchange Molecular Dynamics: A Practical Application Protocol with Solutions to Common Problems and a Peptide Aggregation and Self-Assembly Example.
期刊论文
Methods in molecular biology (Clifton, N.J.), 2018, 卷号: 1777
作者:
Qi Ruxi
;
Wei Guanghong
;
Ma Buyong
;
Nussinov Ruth
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/05
Free energy landscape
GROMACS
Human islet amyloid polypeptide
Molecular dynamics simulations
Protein aggregation
REMD
Replica exchange method
Recent computational studies of membrane interaction and disruption of human islet amyloid polypeptide: Monomers, oligomers and protofibrils
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2018, 卷号: 1860, 期号: 9
作者:
Dong, Xuewei
;
Qiao, Qin
;
Qian, Zhenyu
;
Wei, Guanghong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Human islet amyloid polypeptide
Type 2 diabetes
Amyloid aggregates
Conformational ensemble
Membrane disruption
Molecular dynamics simulations
Effects of tetramethylpyrazine phosphate on pancreatic islet microcirculation in SD rats
期刊论文
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 2018, 卷号: 41, 期号: 4
作者:
Xu, X.
;
Wu, L.
;
Lu, Z. Q.
;
Xia, P.
;
Zhu, X. P.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
TMPP
Islet microcirculation
The non-radioactive microsphere technique
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