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科研机构
北京大学 [6]
厦门大学 [1]
化学研究所 [1]
内容类型
期刊论文 [7]
其他 [1]
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2016 [2]
2014 [1]
2010 [1]
2005 [2]
2000 [1]
1999 [1]
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Conformational Flexibility of a Short Loop near the Active Site of the SARS-3CLpro is Essential to Maintain Catalytic Activity
期刊论文
SCIENTIFIC REPORTS, 2016
Li, Chunmei
;
Teng, Xin
;
Qi, Yifei
;
Tang, Bo
;
Shi, Hailing
;
Ma, Xiaomin
;
Lai, Luhua
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2017/12/03
CORONAVIRUS 3C-LIKE PROTEASE
SUBSTRATE-BINDING
CRYSTAL-STRUCTURE
DIMER INTERFACE
PROTEINASE
MECHANISM
DIMERIZATION
DISSOCIATION
SIMULATIONS
INHIBITOR
Rational design of TNF alpha binding proteins based on the de novo designed protein DS119
期刊论文
PROTEIN SCIENCE, 2016
Zhu, Cheng
;
Zhang, Changsheng
;
Zhang, Tao
;
Zhang, Xiaoling
;
Shen, Qi
;
Tang, Bo
;
Liang, Huanhuan
;
Lai, Luhua
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/04
protein design
protein-protein interaction
TNF
inhibitor
de novo
COMPUTATIONAL DESIGN
KEY RESIDUES
SCAFFOLDS
PAIR
PREDICTION
INTERFACE
EPITOPE
MOTIFS
Design of Novel PLK1 Inhibitors
其他
2014-01-01
云泰康翔
;
覃覃
;
陈芳进
;
刘莹
;
来鲁华
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2015/10/23
PLK1 Inhibitor Domain-domain interface
Maturation Mechanism of Severe Acute Respiratory Syndrome (SARS) Coronavirus 3C-like Proteinase
期刊论文
journal of biological chemistry, 2010
Li, Chunmei
;
Qi, Yifei
;
Teng, Xin
;
Yang, Zongchang
;
Wei, Ping
;
Zhang, Changsheng
;
Tan, Lei
;
Zhou, Lu
;
Liu, Ying
;
Lai, Luhua
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/14
CRYSTAL-STRUCTURE
DIMER INTERFACE
SUBSTRATE-SPECIFICITY
HIV-1 PROTEASE
VIRUS
DIMERIZATION
INHIBITOR
DESIGN
DOMAIN
POLYPROTEIN
The interaction between severe acute respiratory syndrome coronavirus 3C-like proteinase and a dimeric inhibitor by capillary electrophoresis
期刊论文
ANALYTICAL BIOCHEMISTRY, 2005, 卷号: 343, 期号: 1, 页码: 159-165
作者:
Ding, L
;
Zhang, XX
;
Wei, P
;
Fan, KQ
;
Lai, LH
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/04/09
Binding Constants
Capillary Electrophoresis
Interface Inhibitor
Sars 3c-like Proteinase
Thermodynamic Parameters
The interaction between severe acute respiratory syndrome coronavirus 3C-like proteinase and a dimeric inhibitor by capillary electrophoresis
期刊论文
分析生物化学, 2005
Ding, L
;
Zhang, XX
;
Wei, P
;
Fan, KQ
;
Lai, LH
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/11
binding constants
capillary electrophoresis
interface inhibitor
SARS 3C-like proteinase
thermodynamic parameters
MAIN PROTEINASE
SERUM-ALBUMIN
SARS
BINDING
DESIGN
SUBSTRATE
PROTEASE
Construction of protein binding sites in scaffold structures
期刊论文
biopolymers, 2000
Liang, SD
;
Liu, ZJ
;
Li, WZ
;
Ni, LS
;
Lai, LH
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  |  
浏览/下载:2/0
  |  
提交时间:2015/11/11
protein-protein interaction
grafting
barnase-barstar
protein design
BARNASE
BARSTAR
RECOGNITION
INHIBITOR
ENERGY
ENERGETICS
INTERFACE
MUTATIONS
STABILITY
COMPLEX
界面缓蚀剂的吸附稳定性
期刊论文
http://electrochem.xmu.edu.cn/CN/abstract/abstract9425.shtml, 1999
甘复兴
;
汪的华
;
邹津耘
;
Gan Fuxing
;
Wang Dihua
;
Zou Jinyun
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2013/11/18
界面缓蚀剂
吸附稳定性
阳极脱附
电化学振荡
微分极化曲线
Interface inhibitor
Adsorption stability
Anodic desorption
Electrochemical oscillation
Differential polarization curven and adsorption of the inhibitor
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