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中南大学 [7]
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期刊论文 [31]
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Dioscin attenuates high-fat diet-induced insulin resistance of adipose tissue through the IRS-1/PI3K/Akt signaling pathway
期刊论文
MOLECULAR MEDICINE REPORTS, 2019, 卷号: 19, 期号: 2, 页码: 1230-1237
作者:
Li, Haijuan
;
Yu, Lianzhi
;
Zhao, Changsheng
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
dioscin
insulin tolerance
high-fat diet
insulin receptor substrate 1
phosphoinositide 3-kinase
protein kinase B pathway
MicroRNA-1225-5p behaves as a tumor suppressor in human glioblastoma via targeting of IRS1
期刊论文
ONCOTARGETS AND THERAPY, 2018, 卷号: 11
作者:
Chen, Zhuo
;
Li, Dongyuan
;
Chi, Guonan
;
Jin, Xingyi
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
microRNA
microRNA-1225-5p
glioblastoma
insulin receptor substrate 1
prognosis
Effect of ursolic acid on obesity-induced insulin resistance in rat liver
期刊论文
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 2018, 卷号: 17, 期号: 5
作者:
Wang Ziwei
;
Zhou Na
;
Fang Shengbo
;
Zhang Xin
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  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Ursolic acid
Insulin resistance
Liver
Protein tyrosine phosphatase-1B
Insulin receptor substrate-2
Huangqi (astragalus) decoction ameliorates diabetic nephropathy via IRS1-PI3K-GLUT signaling pathway
期刊论文
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2018, 卷号: 10, 期号: 8
作者:
Chen, Xia
;
Wang, Hao
;
Jiang, Minqian
;
Zhao, Jie
;
Fan, Chunling
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Astragalus
insulin receptor substrate1
phosphatidylinositol 3 kinase
glucose transporter
db/db mice
diabetic nephropathy
Huangqi (astragalus) decoction ameliorates diabetic nephropathy via IRS1-PI3K-GLUT signaling pathway
期刊论文
American journal of translational research, 2018, 卷号: 10, 页码: 2491-2501
作者:
Chen Xia[1]
;
Wang Hao[2]
;
Jiang Minqian[3]
;
Zhao Jie[4]
;
Fan Chunling[5]
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/04/22
Astragalus
db/db mice
diabetic nephropathy
glucose transporter
insulin receptor substrate1
phosphatidylinositol 3 kinase
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:
Yang, Xin
;
Xu, Zhipeng
;
Zhang, Chunlan
;
Cai, Zixin
;
Zhang, Jingjing*
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  |  
浏览/下载:37/0
  |  
提交时间:2019/12/03
A1c
glycated hemoglobin
AACE
American Association of Clinical Endocrinologists
ACC
acetyl-CoA carboxylase
ADA
American Diabetes Association
Akt/PKB
tyrosine kinase/protein kinase B
AMP
adenosine monophosphate
AMPK
adenosine monophosphate-activated protein
Ang II
angiotensin II
ATP
adenosine triphosphate
BAT
brown adipose tissue
CHOP
CEBP-homologous protein
CEBP
CCAAT enhancer binding protein
CoA
coenzyme A
DPP
Diabetes Prevention Program
EASD
European Association for the Study of Diabetes
eNOS
endothelial nitric oxide synthase
ER
endoplasmic reticulum
FDA
Food and Drug Administration
FFA
free fatty acid
FOXO1
forkhead box protein O1
G6P
glucose 6-phosphate
GDM
gestational diabetes mellitus
GIPR
glucose-dependent insulinotropic polypeptide receptor
GLP-1R
glucagon-like peptide-1 receptor
GLUT1
glucose transporter-1
GLUT4
glucose transporter type 4
GLUTs
glucose transporters
G6P
glucose 6-phosphate, glucose transporter-1
GPR40
G protein-coupled receptor 40
HbA1c
hemoglobin A1c
HGP
hepatic glucose production
HSL
hormone sensitive lipase
IL-6
interleukin 6
INS-1
insulinoma cells in rat
IR
insulin resistance
IRS-1
insulin receptor substrate 1
JNK
c-Jun. N-terminal kinase
Kir6.2
inwardly rectifying potassium/kalium channel
LDs
lipid droplets
LDL
low density lipoprotein
LV
left ventricular
MIN6 cells
mouse insulinoma cells
MAPK
mitogen-activated protein kinases
mPTP
mitochondrial permeability transition pore opening
mTOR
mammalian target of rapamycin
NADPH
nicotinamide adenine dinucleotide phosphate
NF-kappaB
nuclear factors-kappa B
NIT-1 cells
insulinoma cells
p70S6K
p70 ribosomal S6 kinase
PA
palmitic acid
NOS
NADPH oxidase
p38 MAPK
p38 mitogen-activated protein kinase
PA
palmitic acid
PCOS
polycystic ovary syndrome
PGC-1α
peroxisome proliferator-activated receptor-g coactivator-1α
PI3K
phosphatidylinositol 3-kinase
PKB
protein kinase B
PKC
protein kinase C
PPARα
peroxisome-proliferator activated receptor α
PTP
permeability transition pore
RCT
randomized controlled trial
RISK
reperfusion injury salvage kinase
ROS
reactive oxygen species
SERCA2
reticulum sarcoplasmic Ca2 +-ATPase
RISK
reperfusion injury salvage kinase
Smad3
mothers against decapentaplegic homolog 3
SRC-2
steroid receptor coactivator 2
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TGFβ1
transforming growth factor β1
TLR4
Toll-like receptor
TNF-α
tumor necrosis factor α
TR4
testicular receptor 4
UKPDS
United Kingdom Prospective Diabetes Study
VLDL
very low density lipoprotein
Metformin
Pancreatic β Cells
Heart failure
Insulin sensitizer
MG53: Biological Function and Potential as a Therapeutic Target
期刊论文
MOLECULAR PHARMACOLOGY, 2017
Zhang, Yan
;
Wu, Hong-Kun
;
Lv, Fengxiang
;
Xiao, Rui-Ping
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/12/03
ISCHEMIA-REPERFUSION INJURY
CELL-MEMBRANE REPAIR
INSULIN-RECEPTOR SUBSTRATE-1
E3 UBIQUITIN LIGASES
SKELETAL-MUSCLE
MUSCULAR-DYSTROPHY
METABOLIC SYNDROME
MOLECULAR REGULATION
SIGNALING PATHWAY
MYOCARDIAL INJURY
Effects of the Tangningtongluo formula as an alternative strategy for diabetics via upregulation of insulin receptor substrate-1
期刊论文
2017, 卷号: 16, 期号: 1, 页码: 703-709
作者:
Cheng Long
;
Song Junmei
;
Li Geng
;
Liu Yue
;
Wang Yuming
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/04
hypoglycemic effect
diabetes mellitus
insulin receptor substrate-1
traditional Chinese medicine
Tangningtongluo
胰岛素受体和胰岛素受体底物1在NAFLD大鼠的表达及饮食干预的影响
学位论文
2016, 2015
崔帆
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/06/20
非酒精性脂肪性肝病
胰岛素受体
胰岛素受体底物1
饮食干预
NAFLD
Insulin receptor
Insulin receptor substrate-1
Dietary intervention
Rutaecarpine ameliorates hyperlipidemia and hyperglycemia in fat-fed, streptozotocin-treated rats via regulating the IRS-1/PI3K/Akt and AMPK/ACC2 signaling pathways
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 4
作者:
Nie, Xu-qiang
;
Chen, Huai-hong
;
Zhang, Jian-yong
;
Zhang, Yu-jing
;
Yang, Jian-wen
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
rutaecarpine
metformin
fat-fed, streptozotocin-treated rats
metabolic syndrome
type 2 diabetes
hyperlipidemia
insulin receptor substrate-1
AMPK
acetyl-CoA carboxylase
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