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大连化学物理研究所 [14]
上海中医药大学 [10]
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中国医学科学院 北京... [4]
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期刊论文 [43]
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Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
作者:
Ma, Hong-Ping
;
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2019/06/20
bufotalin
cytochrome P450 3A (CYP3A)
hydroxylation
human liver microsomes (HLMs)
docking simulations
Cytochrome p450 3a enzymes are key contributors for hepatic metabolism of bufotalin, a natural constitute in chinese medicine chansu
期刊论文
Frontiers in pharmacology, 2019, 卷号: 10, 页码: 10
作者:
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
;
Zhang, Feng
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2019/05/08
Bufotalin
Cytochrome p450 3a (cyp3a)
Hydroxylation
Human liver microsomes (hlms)
Docking simulations
Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10
作者:
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
;
Zhang, Feng
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/12/05
bufotalin
cytochrome P450 3A (CYP3A)
hydroxylation
human liver microsomes (HLMs)
docking simulations
In vitro characterization of the glucuronidation pathways of licochalcone A mediated by human UDP-glucuronosyltransferases
期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6
作者:
Xia, Yang-Liu
;
Dou, Tong-Yi
;
Lv, Xia
;
Ge, Guang-Bo
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/05
Licochalcone A
UDP-glucuronosyltransferases (UGTs)
glucuronidation
human liver microsomes (HLM)
In vitro characterization of the glucuronidation pathways of licochalcone A mediated by human UDP-glucuronosyltransferases
期刊论文
XENOBIOTICA, 2019, 卷号: 49, 页码: 671-677
作者:
Xia, Yang-Liu
;
Dou, Tong-Yi
;
Lv, Xia
;
Ge, Guang-Bo
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/02
Licochalcone A
UDP-glucuronosyltransferases (UGTs)
glucuronidation
human liver microsomes (HLM)
Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu
期刊论文
Frontiers in pharmacology, 2019, 卷号: 10, 页码: 52
作者:
Dai Zi-Ru[1]
;
Ning Jing[2]
;
Sun Gui-Bo[3]
;
Wang Ping[4]
;
Zhang Feng[5]
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/04/22
bufotalin
cytochrome P450 3A (CYP3A)
docking simulations
human liver microsomes (HLMs)
hydroxylation
In vitro characterization of the glucuronidation pathways of licochalcone A mediated by human UDP-glucuronosyltransferases
期刊论文
Xenobiotica, the fate of foreign compounds in biological systems, 2019, 卷号: 49, 页码: 671-677
作者:
Xia Yang-Liu[1]
;
Dou Tong-Yi[2]
;
Lv Xia[3]
;
Ge Guang-Bo[4]
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/04/22
Licochalcone A
UDP-glucuronosyltransferases (UGTs)
glucuronidation
human liver microsomes (HLM)
Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu
期刊论文
2019, 卷号: 10, 页码: 52
作者:
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
;
Zhang, Feng
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/01/03
bufotalin
cytochrome P450 3A (CYP3A)
hydroxylation
human liver microsomes (HLMs)
docking simulations
Novel in vitro dynamic metabolic system for predicting the human pharmacokinetics of tolbutamide
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 9
作者:
Cai-fu Xue
;
Zhe Zhang
;
Yan Jin
;
Bin Zhu
;
Jun-fen Xing
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
physiologically based pharmacokinetic model
FAB hydrogel
microdialysis
tolbutamide
Bio-PK metabolic system
dynamic
human liver microsomes
Charactering the metabolism of cryptotanshinone by human P450 enzymes and uridine diphosphate glucuronosyltransferases in vitro
期刊论文
中国药理学报, 2018, 卷号: 39, 期号: 8
作者:
Zeng Jin
;
Fan Yujuan
;
Tan Bo
;
Su Huizong
;
Li Yue
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
cryptotanshinone
P450 enzymes
uridine diphosphate glucuronosyltransferases
metabolic characteristics
human liver microsomes
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