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科研机构
南华大学 [6]
中南大学 [6]
兰州大学 [4]
湖南农业大学 [3]
复旦大学上海医学院 [3]
上海药物研究所 [2]
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期刊论文 [38]
学位论文 [2]
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Celecoxib aggravates atherogenesis and upregulates leukotrienes in ApoE mice and lipopolysaccharide-stimulated RAW264.7 macrophages
期刊论文
Atherosclerosis, 2019
作者:
Yimin Pang
;
Lu Gan
;
Xianzhe Wang
;
Qi Su
;
Cong Liang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/17
Atherosclerosis
COX-2-selective inhibitors
Cyclooxygenase-2
5-Lipoxygenase
Leukotrienes
ApoE-/- mice
RAW264.7 macrophages
Alkaloids as Cyclooxygenase Inhibitors in Anticancer Drug Discovery
期刊论文
CURRENT PROTEIN & PEPTIDE SCIENCE, 2018, 卷号: 19, 期号: 3, 页码: 292-301
作者:
Hashmi, Muhammad Ali
;
Khan, Afsar
;
Farooq, Umar
;
Khan, Sehroon
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2018/05/08
Anticancer
Cyclooxygenase
Cox-2
Alkaloids
Enzyme Inhibition
Anti-inflammatory
Anti-tumor
MiR-216a-3p inhibits colorectal cancer cell proliferation through direct targeting COX-2 and ALOX5
期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2018, 卷号: 119, 期号: 2, 页码: 1755-1766
作者:
Wang, Dongxia
;
Li, Yuechun
;
Zhang, Chun
;
Li, Xianming
;
Yu, Jinming
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/11
5-lipoxygenase (ALOX5) (5-LO)
cell proliferation
colorectal cancer
(CRC)
cyclooxygenase-2 (COX-2)
miR-216a-3p
Vitamin D receptor and cyclooxygenase-2 expression in uterine leiomyoma tissues and their correlation
期刊论文
2018, 卷号: 7, 期号: 1, 页码: 135-141
作者:
Liu, Fujun
;
Zhang, Xiao
;
Yan, Keqin
;
Liang, Jing
;
Deng, Lin
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/03
Uterine leiomyoma
vitamin D receptor (VDR)
cyclooxygenase-2 (COX-2)
Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways
期刊论文
Molecular Immunology, 2018, 卷号: 99, 页码: 115-123
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Chen, Ying
;
Zhu, Cheng-Gen
;
Shi, Jian-Gong
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/27
Akt
protein kinase B
Atg
autophagy related gene
CNS
central nervous system
COX-2
cyclooxygenase-2
CQ
chloroquine
ERK
extracellular signal-regulated kinase
IL-1β
interleukin-1β
iNOS
inducible nitric oxide synthase
JNK
c-jun NH2-terminal kinase
LPS
Lipopolysaccharide
MAPKs
mitogen-activated protein kinases
mTOR
mechanistic target of rapamycin
NO
nitric oxide
PI3K
phosphatidylinositol 3-kinase
PRR
pattern recognition receptor
TLR4
toll like receptor 4
TNF-α
tumor necrosis factor-α
20C
Autophagy
Mitogen-activated protein kinases (MAPKs)
Toll like receptor 4 (TLR4)
Protein kinase B (Akt)
Mechanistic target of rapamycin (mTOR)
Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways
期刊论文
Molecular immunology, 2018, 卷号: 99, 页码: 115-123
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Chen, Ying
;
Zhu, Cheng-Gen
;
Shi, Jian-Gong
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/27
Akt
protein kinase B
Atg
autophagy related gene
CNS
central nervous system
COX-2
cyclooxygenase-2
CQ
chloroquine
ERK
extracellular signal-regulated kinase
IL-1β
interleukin-1β
iNOS
inducible nitric oxide synthase
JNK
c-jun NH2-terminal kinase
LPS
Lipopolysaccharide
MAPKs
mitogen-activated protein kinases
mTOR
mechanistic target of rapamycin
NO
nitric oxide
PI3K
phosphatidylinositol 3-kinase
PRR
pattern recognition receptor
TLR4
toll like receptor 4
TNF-α
tumor necrosis factor-α
20C
Autophagy
Mitogen-activated protein kinases (MAPKs)
Toll like receptor 4 (TLR4)
Protein kinase B (Akt)
Mechanistic target of rapamycin (mTOR)
环氧合酶-2介导镉诱导肾损伤的内质网应激调控机制研究
学位论文
2017, 2016
骆冰
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2017/06/20
镉
环氧合酶2 (COX-2)
内质网(ER)应激
自噬
肾毒性损伤
cadmium
cyclooxygenase-2 (COX-2)
endoplasmic reticulum (ER) stress
autophagy
nephrotoxicity
Activated hepatic stellate cells directly induce pathogenic Th17 cells in chronic hepatitis B virus infection
期刊论文
EXPERIMENTAL CELL RESEARCH, 2017, 卷号: 359, 期号: 1
作者:
Liv, Yun
;
Li, Lei
;
Liu, Jiang
;
She, Wei-min
;
Shi, Jie-Min
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Chronic hepatitis B
Hepatic stellate cells (HSCs)
Th17 cells
Cyclooxygenase-2 (COX-2)
Prostaglandin E2 (PGE2)
Soy protein-derived ACE-inhibitory peptide LSW (Leu-Ser-Trp) shows anti-inflammatory activity on vascular smooth muscle cells
期刊论文
Journal of Functional Foods, 2017, 卷号: 34, 页码: 248-253
作者:
Lin, Qinlu
;
Liao, Wang
;
Bai, Jie
;
Wu, Wei
;
Wu, Jianping*
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/28
CVD
cardiovascular disease
ACE
angiotensin converting enzyme
Ang II
angiotensin II
LSW
Leu-Ser-Trp
VSMC
vascular smooth muscle cell
IRW
Ile-Arg-Trp
COX-2
cyclooxygenase 2
iNOS
inducible nitric oxide synthase
AT1R
angiotensin type I receptor
ERK1/2
extracellular signal regulated kinases 1 and 2
ROS
reactive oxygen species
DHE
dihydroethidium
IQW
Ile-Gln-Trp
Soy protein
ACE-inhibitory peptide
LSW
VSMC
Inflammation
Stauntoside B inhibits macrophage activation by inhibiting NF-κB and ERK MAPK signalling
期刊论文
Pharmacological Research, 2016, 卷号: 111, 期号: Volume 111, 页码: 303-315
作者:
Liu, Jianxin
;
Tang, Jinshan
;
Zuo, Yihan
;
Yu, Yang
;
Luo, Pei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/03
NO
nitric oxide
PGE2
prostaglandin E2
NSAIDs
non-steroidal anti-inflammatory drugs
qRT-PCR
quantitative real-time polymerase chain reaction
LPS
lipopolysaccharide
IFN-γ
interferon γ
G-CSF
granulocyte colony stimulating factor
TNF-α
tumor necrosis factor-α
IL-1β
interleukin-1β
IL-6
interleukin-6
MCP-1
monocyte chemoattractant protein-1
NF-κB
Nuclear factor-κB
IκB
inhibitory protein
IKK
IκB kinase
RPS3
ribosomal protein S3
iNOS
inducible nitric oxide synthase
COX-2
cyclooxygenase-2
PGESs
prostaglandin E2 synthases
mPGES-1
microsomal prostaglandin synthetase-1
mPGES-2
microsomal prostaglandin E synthase-2
cPGES
cytosolic prostaglandin E synthase
MAPK
mitogen-activated protein kinases
ERK
extracellular signal-regulated kinase
JNK
c- Jun N-terminal kinase
PGI2
prostacyclin I2
PGD2
prostaglandin D2
PGF2α
prostaglandin F2α
TXA2
thromboxane A2
Stauntoside B (PubChem CID: 101010462)
Stauntoside B
Cynanchi stauntonii
Lipopolysaccharide
Anti-inflammatory activity
NF-κB
MAPK
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