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上海药物研究所 [3]
北京大学 [2]
兰州大学 [2]
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南华大学 [1]
厦门大学 [1]
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期刊论文 [16]
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Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:
Yang, Xin
;
Xu, Zhipeng
;
Zhang, Chunlan
;
Cai, Zixin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/12/03
A1c
glycated hemoglobin
AACE
American Association of Clinical Endocrinologists
ACC
acetyl-CoA carboxylase
ADA
American Diabetes Association
Akt/PKB
tyrosine kinase/protein kinase B
AMP
adenosine monophosphate
AMPK
adenosine monophosphate-activated protein
Ang II
angiotensin II
ATP
adenosine triphosphate
BAT
brown adipose tissue
CHOP
CEBP-homologous protein
CEBP
CCAAT enhancer binding protein
CoA
coenzyme A
DPP
Diabetes Prevention Program
EASD
European Association for the Study of Diabetes
eNOS
endothelial nitric oxide synthase
ER
endoplasmic reticulum
FDA
Food and Drug Administration
FFA
free fatty acid
FOXO1
forkhead box protein O1
G6P
glucose 6-phosphate
GDM
gestational diabetes mellitus
GIPR
glucose-dependent insulinotropic polypeptide receptor
GLP-1R
glucagon-like peptide-1 receptor
GLUT1
glucose transporter-1
GLUT4
glucose transporter type 4
GLUTs
glucose transporters
G6P
glucose 6-phosphate, glucose transporter-1
GPR40
G protein-coupled receptor 40
HbA1c
hemoglobin A1c
HGP
hepatic glucose production
HSL
hormone sensitive lipase
IL-6
interleukin 6
INS-1
insulinoma cells in rat
IR
insulin resistance
IRS-1
insulin receptor substrate 1
JNK
c-Jun. N-terminal kinase
Kir6.2
inwardly rectifying potassium/kalium channel
LDs
lipid droplets
LDL
low density lipoprotein
LV
left ventricular
MIN6 cells
mouse insulinoma cells
MAPK
mitogen-activated protein kinases
mPTP
mitochondrial permeability transition pore opening
mTOR
mammalian target of rapamycin
NADPH
nicotinamide adenine dinucleotide phosphate
NF-kappaB
nuclear factors-kappa B
NIT-1 cells
insulinoma cells
p70S6K
p70 ribosomal S6 kinase
PA
palmitic acid
NOS
NADPH oxidase
p38 MAPK
p38 mitogen-activated protein kinase
PA
palmitic acid
PCOS
polycystic ovary syndrome
PGC-1α
peroxisome proliferator-activated receptor-g coactivator-1α
PI3K
phosphatidylinositol 3-kinase
PKB
protein kinase B
PKC
protein kinase C
PPARα
peroxisome-proliferator activated receptor α
PTP
permeability transition pore
RCT
randomized controlled trial
RISK
reperfusion injury salvage kinase
ROS
reactive oxygen species
SERCA2
reticulum sarcoplasmic Ca2 +-ATPase
RISK
reperfusion injury salvage kinase
Smad3
mothers against decapentaplegic homolog 3
SRC-2
steroid receptor coactivator 2
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TGFβ1
transforming growth factor β1
TLR4
Toll-like receptor
TNF-α
tumor necrosis factor α
TR4
testicular receptor 4
UKPDS
United Kingdom Prospective Diabetes Study
VLDL
very low density lipoprotein
Metformin
Pancreatic β Cells
Heart failure
Insulin sensitizer
Activity-dependent dephosphorylation of paxillin contributed to nociceptive plasticity in spinal cord dorsal horn
期刊论文
PAIN, 2016, 卷号: 157, 期号: 3, 页码: 652-665
作者:
Wang, XT
;
Zheng, R
;
Suo, ZW
;
Liu, YN
;
Zhang, ZY
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/01/11
Paxillin
C-terminal Src kinase
Protein tyrosine phosphatases
Synaptic plasticity
Pain
Steroid receptor RNA activator: Biologic function and role in disease
期刊论文
Clinica Chimica Acta, 2016, 卷号: 459, 页码: 137-146
作者:
Liu, Chan
;
Wu, Hong-Tao
;
Zhu, Neng
;
Shi, Ya-Ning
;
Liu, Zheng
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2019/12/03
AF-2
activation function-2
AR
androgen receptor
C/EBPα
ccaat-enhancer-binding protein α
CTCF
CCCTC-binding factor
Ddx5
DEAD box protein 5
ERα
estrogen receptor α
GR
glucocorticoid receptor
Hes1
hairy and enhancer of split-1
HP1γ
heterochromatin protein 1γ
JNK
c-Jun N-terminal kinases
lncRNA
long noncoding RNA
MyoD
myogenic differentiation 1
NANOG
homeobox protein NANOG
NR
nuclear receptor(s)
p38 MAPK
mitogen-activated protein kinase
PACT
protein kinase RNA activator
PCOS
polycystic ovary syndrome
PKR
protein kinase RNA-dependent
PPARγ
Peroxisome Proliferator-Activated Receptor gamma
PR
progesterone receptor
PRC2
polycomb repressive complex 2
preTCRα
pre T-cell antigen receptor alpha
Pus1p
pseudouridine synthesis protein
RAR
retinoic acid receptor
RBP-J
recombination signal-binding protein J
RRM
RNA recognition motif
SF-1
steroidogenic factor 1
SHARP
retinoid and thyroid hormone receptors (SMRT)/HDAC1-associated repressor protein
SLIRP
stem-loop loop-interacting RNA RNA-binding protein
SRA
Steroid receptor RNA activator
SRAP
steroid receptor RNA activator protein
SRC-1
steroid receptor coactivator-1
STR
stem-loop structure
TNFα
tumor necrosis factor α
TRBP
transactivation response RNA-binding protein
TrxG
trithorax group
SRA
Long noncoding RNAs
Nuclear receptor
Transcriptional coactivator
Role of the PKC alpha-c-Src tyrosine kinase pathway in the mediation of p120-catenin degradation in ventilator-induced lung injury
期刊论文
RESPIROLOGY, 2016, 卷号: 21, 期号: 8, 页码: 1404-1410
作者:
Zhao, Tao
;
Zhao, Hongwei
;
Li, Gang
;
Zheng, Shengfa
;
Liu, Mengjie
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/16
c-Src kinase
p120-catenin
phosphorylation
protein kinase C
ventilation-induced lung injury
Steroid receptor RNA activator: Biologic function and role in disease
期刊论文
Clinica Chimica Acta, 2016, 卷号: 459, 页码: 137-146
作者:
Liu, Chan
;
Wu, Hong-Tao
;
Zhu, Neng
;
Shi, Ya-Ning
;
Liu, Zheng
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2019/12/27
AF-2
activation function-2
AR
androgen receptor
C/EBPα
ccaat-enhancer-binding protein α
CTCF
CCCTC-binding factor
Ddx5
DEAD box protein 5
ERα
estrogen receptor α
GR
glucocorticoid receptor
Hes1
hairy and enhancer of split-1
HP1γ
heterochromatin protein 1γ
JNK
c-Jun N-terminal kinases
lncRNA
long noncoding RNA
MyoD
myogenic differentiation 1
NANOG
homeobox protein NANOG
NR
nuclear receptor(s)
p38 MAPK
mitogen-activated protein kinase
PACT
protein kinase RNA activator
PCOS
polycystic ovary syndrome
PKR
protein kinase RNA-dependent
PPARγ
Peroxisome Proliferator-Activated Receptor gamma
PR
progesterone receptor
PRC2
polycomb repressive complex 2
preTCRα
pre T-cell antigen receptor alpha
Pus1p
pseudouridine synthesis protein
RAR
retinoic acid receptor
RBP-J
recombination signal-binding protein J
RRM
RNA recognition motif
SF-1
steroidogenic factor 1
SHARP
retinoid and thyroid hormone receptors (SMRT)/HDAC1-associated repressor protein
SLIRP
stem-loop loop-interacting RNA RNA-binding protein
SRA
Steroid receptor RNA activator
SRAP
steroid receptor RNA activator protein
SRC-1
steroid receptor coactivator-1
STR
stem-loop structure
TNFα
tumor necrosis factor α
TRBP
transactivation response RNA-binding protein
TrxG
trithorax group
SRA
Long noncoding RNAs
Nuclear receptor
Transcriptional coactivator
Steroid receptor RNA activator: Biologic function and role in disease
期刊论文
Clinica Chimica Acta, 2016, 卷号: 459, 页码: 137-146
作者:
Liu, Chan
;
Wu, Hong-Tao
;
Zhu, Neng
;
Shi, Ya-Ning
;
Liu, Zheng
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2019/12/27
AF-2
activation function-2
AR
androgen receptor
C/EBPα
ccaat-enhancer-binding protein α
CTCF
CCCTC-binding factor
Ddx5
DEAD box protein 5
ERα
estrogen receptor α
GR
glucocorticoid receptor
Hes1
hairy and enhancer of split-1
HP1γ
heterochromatin protein 1γ
JNK
c-Jun N-terminal kinases
lncRNA
long noncoding RNA
MyoD
myogenic differentiation 1
NANOG
homeobox protein NANOG
NR
nuclear receptor(s)
p38 MAPK
mitogen-activated protein kinase
PACT
protein kinase RNA activator
PCOS
polycystic ovary syndrome
PKR
protein kinase RNA-dependent
PPARγ
Peroxisome Proliferator-Activated Receptor gamma
PR
progesterone receptor
PRC2
polycomb repressive complex 2
preTCRα
pre T-cell antigen receptor alpha
Pus1p
pseudouridine synthesis protein
RAR
retinoic acid receptor
RBP-J
recombination signal-binding protein J
RRM
RNA recognition motif
SF-1
steroidogenic factor 1
SHARP
retinoid and thyroid hormone receptors (SMRT)/HDAC1-associated repressor protein
SLIRP
stem-loop loop-interacting RNA RNA-binding protein
SRA
Steroid receptor RNA activator
SRAP
steroid receptor RNA activator protein
SRC-1
steroid receptor coactivator-1
STR
stem-loop structure
TNFα
tumor necrosis factor α
TRBP
transactivation response RNA-binding protein
TrxG
trithorax group
SRA
Long noncoding RNAs
Nuclear receptor
Transcriptional coactivator
The G beta gamma-Src signaling pathway regulates TNF-induced necroptosis via control of necrosome translocation
期刊论文
http://dx.doi.org/10.1038/cr.2014.17, 2014
Li, Lisheng
;
Chen, Wanze
;
Liang, Yaoji
;
Ma, Huabin
;
Li, Wenjuan
;
Zhou, Zhenru
;
Li, Jie
;
Ding, Yan
;
Ren, Junming
;
Lin, Juan
;
Han, Felicia
;
Wu, Jianfeng
;
Han, Jiahuai
;
韩家淮
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/07/22
INDUCED CELL-DEATH
PROTEIN-COUPLED RECEPTOR
VOLTAGE-DEPENDENT MODULATION
MIXED LINEAGE KINASE
SMOOTH-MUSCLE-CELLS
L929 CELLS
C-SRC
PROGRAMMED NECROSIS
TYROSINE PHOSPHORYLATION
MEDIATED CYTOTOXICITY
Nanomaterial-based tools for protein kinase bioanalysis.
期刊论文
Trends in Analytical Chemistry, 2014, 卷号: Vol.58, 页码: 40-53
作者:
Liu, Xin
;
Li, Yong
;
Xu, Xiahong
;
Li, Pei
;
Nie, Zhou
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/31
3,3′,5,5′-tetramethylbenzidine (TMB)
Adenosine-5′-diphosphate (ADP)
Adenosine-5′-triphosphate (ATP)
Carbonnanotube (CNT)
Carboxypeptidase Y (CPY)
Conjugated polymer nanoparticle (CPN)
Differential pulse voltammetry (DPV)
Electrochemiluminescence (ECL)
Fluorescein isothiocyanate (FITC)
Fluorescence resonance-energy transfer (FRET)
Gold nanoparticle (AuNP)
Gold nanorod (AuNR)
Graphene oxide (GO)
Graphene quantum dot (GQD)
Half-maximal inhibitory concentration (IC50)
Horseradish peroxidase (HRP)
Indium-tin oxide (ITO)
Isobutylmethylxanthine (IBMX)
Leukocyte-specific protein tyrosine kinase (LCK)
Magnetic nanoparticle (MNP)
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS)
Multi-walled carbon nanotube (MWCNT)
Nanoparticle (NP)
Near infrared (NIR)
Poly(aspartic acid) (PAA)
Polyelectrolyte poly(ethyleneimine) (PEI)
Polyion-induced complex (PIC)
Poly[(9,9-bis(3′-N,N-bis(2″-carboxyethyl)amino)propyl)fluorenylene phenylene] (PFPaa)
Protein kinase A (PKA)
Protein kinase C (PKC)
Quantum dot (QD)
Quartz-crystal microbalance (QCM)
Resonance light scattering (RLS)
Ru(II) encapsulated phosphorylate-terminated silica nanoparticle (R-PSiNP)
Silver nanoparticle (AgNP)
Square wave voltammetry (SWV)
Src homology 2 (SH2)
Surface-enhanced Raman spectroscopy (SERS)
Surface-plasmon resonance (SPR)
Tetraethyl rhodamine isothiocyanate (TRITC)
Tetramethyl rhodamine (TAMRA)
TiO2-coated Fe3O4/SiO2 magnetic microsphere (TMSP)
Tris-(2.2′-bipyridyl) ruthenium (TBR)
Ultraviolet-visible (UV-vis)
Zr4+-functionalized mesoporous SiO2 microsphere (ZrMM)
Zr4+-immobilized nitrilotriacetic acid-coated magnetic nanoparticle (Zr-NTA MNP)
Trans-3,4,5,4 '-tetramethoxystilbene, a resveratrol analog, potently inhibits angiogenesis in vitro and in vivo
期刊论文
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 9
作者:
Chen, LK
;
Qiang, PF
;
Xu, QP
;
Zhao, YH
;
Dai, F
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2014/12/05
angiogenesis
trans-3,4,5,4 '-tetramethoxystilbene
resveratrol
endothelial cell
VEGF
VEGF receptor 2
c-Src
Erk1/2
Akt
mTOR
focal adhesion kinase (FAK)
ribosomal protein S6 kinase (p70S6K)
Vagal Efferent Fiber Stimulation Ameliorates Pulmonary Microvascular Endothelial Cell Injury by Downregulating Inflammatory Responses
期刊论文
INFLAMMATION, 2013, 卷号: 36, 期号: 6
作者:
Chen, Chao
;
Zhang, Ying
;
Du, Zhaohui
;
Zhang, Min
;
Niu, Li
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
vagal stimulation
lipopolysaccharide
acute lung injury
Src-suppressed C kinase substrate
E-selectin
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