×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [13]
厦门大学 [12]
北京大学 [8]
复旦大学上海医学院 [8]
清华大学 [4]
中南大学 [4]
更多...
内容类型
期刊论文 [77]
发表日期
2019 [3]
2018 [6]
2017 [5]
2016 [1]
2015 [6]
2014 [5]
更多...
学科主题
Neuroscien... [4]
Biochemist... [3]
Cell Biolo... [1]
Neuroscien... [1]
Pharmacolo... [1]
Research &... [1]
更多...
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共77条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Regulatory role of Golgi brefeldin A resistance factor-1 in amyloid precursor protein trafficking, cleavage and A beta formation
期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 卷号: 120, 期号: 9
作者:
Liu, Kaifei
;
Liu, Ying
;
Xu, Yanting
;
Nandakumar, Kutty Selva
;
Shen, Xiaoyan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
amyloid precursor protein
beta-amyloid peptide
endoplasmic reticulum stress
Golgi brefeldin A resistance factor 1
transmembrane trafficking
The correlation between accumulation of amyloid beta with enhanced neuroinflammation and cognitive impairment after intraventricular hemorrhage
期刊论文
JOURNAL OF NEUROSURGERY, 2019, 卷号: 131, 期号: 1
作者:
Jiang, Conglin
;
Zou, Xiang
;
Zhu, Renqing
;
Shi, Yimin
;
Wu, Zehan
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2019/12/05
intraventricular hemorrhage
amyloid beta
beta-site amyloid precursor protein cleaving enzyme-1
BACE1
neuroinflammation
ferritin
c-Jun N-terminal kinase
JNK
vascular disorders
OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice.
期刊论文
BBA - Molecular Basis of Disease, 2019, 卷号: Vol.1865 No.1, 页码: 161-180
作者:
Yuan, Chunling
;
Guo, Xiaoli
;
Zhou, Qifan
;
Du, Fangyu
;
Jiang, Wei
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/12/17
ALZHEIMER'S
disease
*MILD
cognitive
impairment
*SECRETASE
inhibitors
*AMYLOID
beta-protein
precursor
*SMALL
molecules
A pectin from fruits of Lycium barbarum L. decreases Beta-amyloid peptide production through modulating APP processing
期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 201, 页码: 65-74
作者:
Zhou, Lishuang
;
Liao, Wenfeng
;
Zeng, Hui
;
Yao, Yanli
;
Chen, Xia
收藏
  |  
浏览/下载:159/0
  |  
提交时间:2019/01/08
Lycium barbarum L.
Pectin
A beta(42)
Alzheimer's disease
Amyloid precursor protein processing
Iron dysregulates APP processing accompanying with sAPP alpha cellular retention and beta-secretase inhibition in rat cortical neurons
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 2, 页码: 177-183
作者:
Chen, Yu-ting
;
Chen, Wu-yan
;
Huang, Xiao-tian
;
Xu, Ye-chun
;
Zhang, Hai-yan
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
iron
neurons
amyloid precursor protein
sAPP alpha
beta-amyloid
beta-secretase
Alzheimer's disease
Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2018, 卷号: 279
作者:
Wang, Pengzhen
;
Zheng, Xiaoyao
;
Guo, Qian
;
Yang, Peng
;
Pang, Xiaoying
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/05
Neuronal siRNA delivery
Blood-brain barrier (BBB)
beta-site amyloid precursor protein cleaving enzyme 1 (BACE1)
Cationic nanocomplexes
Alzheimer's disease
Visualization of Alzheimer's Disease Related alpha-/beta-/gamma-Secretase Ternary Complex by Bimolecular Fluorescence Complementation Based Fluorescence Resonance Energy Transfer
期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018, 卷号: 11, 期号: 1, 页码: 431
作者:
Wang, Xin
;
Pei, Gang
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/04/28
Amyloid Precursor Protein
Beta-secretase
App
Site
Cleavage
Adam10
Bace1
Localization
Dimerization
Endocytosis
Myelin injury in the central nervous system and Alzheimer's disease
期刊论文
Brain Research Bulletin, 2018, 卷号: 140, 页码: 162-168
作者:
Wang, Sha-Sha
;
Zhang, Zhao
;
Zhu, Tian-Bi
;
Chu, Shi-Feng
;
He, Wen-Bin
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/27
OLG
oligodendrocyte
CNS
central nervous system
SC
Schwann cell
PNS
peripheral nervous system
MBP
myelin basic protein
PLP
proteolipid protein
P0/MPZ
myelin protein zero
EAE
experimental allergic encephalomyelitis
MS
multiple sclerosis
CNP
2′ 3′-cyclic nucleotide 3′-phosphodiesterase
MAG
myelin associated glycoprotein
MOG
myelin oligodendrocyte glycoprotein
AD
Alzheimer's disease
OPC
oligodendrocyte precursor cell
NPC
neural progenitor cell
ROS
reactive oxygen species
TNF
tumour necrosis factor
AIF
apoptosis-inducing factor
IFN-γ
interferon gamma
ERK1/2
extracellular signal-regulated kinases-1 and -2
MAPK
mediators of mitogen-activated protein kinase
FGFR1/2
fibroblast growth factor receptors-1 and -2
Dock3
dedicator of cytokinesis 3
PERK
pancreatic endoplasmic reticulum kinase
GEF
guanine nucleotide exchange factor
SIRT2
sirtuin 2
NOD2
Nucleotide-binding oligomerization domain containing protein 2
RIPK2
receptor-interacting serine/threonine kinase 2
Shh
Sonic Hedgehog
NMO
neuromyelitis optica
ADEM
acute disseminated encephalomyelitis
ANHLE
acute necrotizing hemorrhagic leukoencephalitis
CPM
central pontine myelinolysis
Aβ
beta-amyloid
SP
senile plaque
NFT
neurofibrillary tangle
MRI
magnetic resonance imaging
Myelin
Oligodendrocyte
Demyelination
Neurodegenerative diseases
Alzheimer’s disease
Effect of microenvironment on beta-site amyloid precursor protein cleaving enzyme 1 expression in PC12 Cells
期刊论文
Journal of Shanghai Jiaotong University .Medical Science, 2018, 卷号: 38, 期号: 9, 页码: 1005-1012
作者:
Yang Huanqing
;
He Xiang
;
Du Xiaoguang
;
Xiao Shifu
;
Wang Tao
收藏
  |  
浏览/下载:136/0
  |  
提交时间:2019/01/08
Alzheimer's disease
microenvironment
PC12 cell
beta-site amyloid precursor protein cleaving enzyme 1 (BACE1)
amyloid-beta peptide (Abeta)
Defining the minimum substrate and charge recognition model of gamma-secretase
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 10, 页码: 1412-1424
作者:
Yan, Yan
;
Xu, Ting-Hai
;
Melcher, Karsten
;
Xu, H. Eric
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Alzheimer's disease
amyloid beta (A beta)
amyloid precursor protein (APP)
C99, gamma-secretase
minimum substrate
Notch protein
recognition model
©版权所有 ©2017 CSpace - Powered by
CSpace