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科研机构
北京大学 [1]
生物物理研究所 [1]
华中师范大学 [1]
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期刊论文 [3]
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2014 [1]
2012 [1]
2010 [1]
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Cell Biolo... [1]
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Epigenetic targets and drug discovery: Part 1: Histone methylation
期刊论文
Pharmacology and Therapeutics, 2014, 卷号: 143, 期号: 3, 页码: 275-294
作者:
Liu, Yanli
;
Liu, Ke
;
Qin, Su
;
Xu, Chao
;
Min, Jinrong*
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/23
Epigenetics
Histone methylation
Inhibitor
Chemical probe
Cancer
PTM
posttranslational modification
HMTs
histone methyltrans-ferases
SET
Suv39, E(z) and Trithorax
SUV39
Su(var)3-9
SUV420
histone-lysine N-methyltransferase SUV420
G9a
euchromatic histone-lysine N-methyltransferase 2
GLP
G9a-like protein 1
Wiz
widely-interspaced zinc finger-containing protein
CDYL1
chromodomain Y-like protein
ACIN1
apoptotic chromatin condensation inducer in the nucleus
SAH
S-adenosyl-l-homocysteine
l
SAM
S-adenosylmethionine
Dot1
disruptor of telomeric silencing
Dot1L
DOT1-Like protein
EZH1
Enhancer of zeste homolog 1
EZH2
Enhancer of zeste homolog 2
Hox
homeotic box
PcG
Polycomb group
PRC1
Polycomb Repressive Complex 1
PRC2
Polycomb Repressive Complex 2
DZNep
3-Deazan- eplanocin A
SMYD2
SET and MYND domain-containing protein 2
PRMT
protein arginine methyltransferases
AMI-1
arginine methyltransferase inhibitor-1
MBT
Malignant Brain Tumor
PEV
position-effect variegation
HSPC
hematopoietic stem and progenitor cells
ChIP
chromatin immunoprecipitation
PK
pharmacokinetic
Linking DNA replication to heterochromatin silencing and epigenetic inheritance
期刊论文
acta biochimica et biophysica sinica, 2012
Li, Qing
;
Zhang, Zhiguo
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  |  
浏览/下载:3/0
  |  
提交时间:2015/11/16
epigenetic inheritance
DNA replication
DNA replication-coupled nucleosome assembly
heterochromatin silencing
ORIGIN RECOGNITION COMPLEX
CELL NUCLEAR ANTIGEN
ASSEMBLY FACTOR-I
POSITION-EFFECT VARIEGATION
CHROMATIN-REMODELING COMPLEX
H3 LYSINE-9 METHYLATION
RNA-POLYMERASE-II
MATING-TYPE LOCI
SACCHAROMYCES-CEREVISIAE
HISTONE H3
Drosophila CAF-1 regulates HP1-mediated epigenetic silencing and pericentric heterochromatin stability
期刊论文
JOURNAL OF CELL SCIENCE, 2010, 卷号: 123, 期号: 16, 页码: 2853-2861
Huang, Hai
;
Yu, Zhongsheng
;
Zhang, Shuaiqi
;
Liang, Xuehong
;
Chen, Jianming
;
Li, Changqing
;
Ma, Jun
;
Jiao, Renjie
;
焦仁杰
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2013/12/24
Drosophila
CAF-1 p180
Heterochromatin
Histone modification
Position effect variegation
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