Linking DNA replication to heterochromatin silencing and epigenetic   inheritance

doi:10.1093/abbs/gmr107

CORC > 北京大学 > 生命科学学院

	Linking DNA replication to heterochromatin silencing and epigenetic inheritance
	Li, Qing ; Zhang, Zhiguo
刊名	acta biochimica et biophysica sinica
	2012
关键词	epigenetic inheritance DNA replication DNA replication-coupled nucleosome assembly heterochromatin silencing ORIGIN RECOGNITION COMPLEX CELL NUCLEAR ANTIGEN ASSEMBLY FACTOR-I POSITION-EFFECT VARIEGATION CHROMATIN-REMODELING COMPLEX H3 LYSINE-9 METHYLATION RNA-POLYMERASE-II MATING-TYPE LOCI SACCHAROMYCES-CEREVISIAE HISTONE H3
DOI	10.1093/abbs/gmr107
英文摘要	Chromatin is organized into distinct functional domains. During mitotic cell division, both genetic information encoded in DNA sequence and epigenetic information embedded in chromatin structure must be faithfully duplicated. The inheritance of epigenetic states is critical in maintaining the genome integrity and gene expression state. In this review, we will discuss recent progress on how proteins known to be involved in DNA replication and DNA replication-coupled nucleosome assembly impact on the inheritance and maintenance of heterochromatin, a tightly compact chromatin structure that silences gene transcription. As heterochromatin is important in regulating gene expression and maintaining genome stability, understanding how heterochromatin states are inherited during S phase of the cell cycle is of fundamental importance.; Biochemistry & Molecular Biology; Biophysics; SCI(E); 中国科技核心期刊(ISTIC); 0; REVIEW; 1,SI; 3-13; 44
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/393981]
专题	生命科学学院
推荐引用方式 GB/T 7714	Li, Qing,Zhang, Zhiguo. Linking DNA replication to heterochromatin silencing and epigenetic inheritance[J]. acta biochimica et biophysica sinica,2012.
APA	Li, Qing,&Zhang, Zhiguo.(2012).Linking DNA replication to heterochromatin silencing and epigenetic inheritance.acta biochimica et biophysica sinica.
MLA	Li, Qing,et al."Linking DNA replication to heterochromatin silencing and epigenetic inheritance".acta biochimica et biophysica sinica (2012).