AUC-ROC,  area  under  receiver  operating  characteristic  BHB,  β-hydroxybutyric  acid  Biomarkers  C,  control  group  CA,  cholic  acid  CPT-11,  irinotecan  Complicating  toxicity  DBIL,  direct  bilirubin  DCA,  deoxycholic  acid  Diarrhea  FDR,  false  discovery  rate  GCA,  glycocholic  acid  Gastrointestinal  toxicity  IBIL,  indirect  bilirubin  IT-TOF/MS,  ion  trap/time-offlight  hybrid  mass  spectrometry  Individual  differences  Irinotecan  Lys,  lysine  MSTFA,  N-methyl-N-trifluoroacetamide  Metabolomics  NS,  non-sensitive  group  NSgt,  non-sensitive  for  gastrointestinal  toxicity  NSmt,  non-sensitive  for  myelosuppression  toxicity  OPLS-DA,  orthogonal  partial  least-squares-discriminant  analysis  PCA,  principal  component  analysis  PLS-DA,  partial  least-squares-discriminant  analysis  Phe,  phenylalanine  Prediction  QC,  quality  control  RSD,  relative  standard  deviation  S,  sensitive  group  Sgt,  sensitive  for  gastrointestinal  toxicity  Smt,  sensitive  for  myelosuppression  toxicity  T,  CPT-11  treated  group  Trp,  tryptophan  UFLC,  ultrafast  liquid  chromatography  VIP,  variable  importance  in  the  projection  pFDR,  false-discovery-rate-adjusted  P  value  

BP neural network  Development cost  General aviation aircraft  Gray correlation analysis  Linear regression  P value analysis  Parametric modeling  Preliminary prediction  Sensitivity analysis  

Interferometry is a very important method in high accuracy measurement for optical system. This article briefly introduced the conception of interferometry and took a product of 4D Technology as an example to carry on the measurement. A large-scale optic-electrical Theodolite in assemblage was measured  and its primary mirror was 400mm in diameter. With the analysis of the results  some micro adjustments of the mechanical structure proceed  and it made the system perform better. The final results of the whole system is 1.061 in P-V value and 0.1136 in RMS value (=632.8nm)  this meets the demand of optical design and practical application. The result demonstrates that interferometry is a good way to be utilized and optimize in the procedure of assemble. (2013) Trans Tech Publications  Switzerland.  

With the development of the resolution of spaceborne remote sensor  the diameter of the primary mirror of spaceborne telescope becomes larger and larger. The distortion of primary mirror which is influenced by the mirror material  structure  self-weight  support system and temperature environment affects optical image quality finally. In this paper  an on-axis TMA high-resolution Cassegrain optical payload with a primary mirror whose diameter is 650mm was designed and the effects of the influence factors of the distortion acts on the on-axis TMA optical system primary mirror had been analyzed by means of Finite Element Analysis. During work  the technology of the primary mirror design had been summarized and general consideration of the primary mirror design technology also had been described at the same time. Considering the telescope manufacture and work station  a reasonable and optimal structure of the primary mirror sub-assembly is taken finally. In the end  the distortion of the primary mirror during its fabrication station and work station had been analyzed by integrated Finite Element Analysis Method. The results implicated the synthesis profile error (P-V value) for the primary mirror is less than /10 and all the indexes of the primary mirror satisfy the requirements of the optical system.