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复旦大学上海医学院 [6]
武汉大学 [4]
上海大学 [3]
清华大学 [2]
北京大学 [1]
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期刊论文 [22]
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Oligomannuronate prevents mitochondrial dysfunction induced by IAPP in RINm5F islet cells by inhibition of JNK activation and cell apoptosis
期刊论文
Chinese Medicine, 2020, 卷号: 15, 期号: 1, 页码: 1-12.
作者:
Xi Liu
;
Qiong Li
;
Xiaolei Cheng
;
Zhichun Liu
;
Xiaoliang Zhao
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/03/10
Oligomannuronate
Type 2 diabetes
Islet amyloid polypeptide
JNK activation
Mitochondrial dysfunction
RINm5F cells
The Inhibitory Effect of Hydroxylated Carbon Nanotubes on the Aggregation of Human Islet Amyloid Polypeptide Revealed by a Combined Computational and Experimental Study
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 11
作者:
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
protein aggregation
human islet amyloid polypeptide
hydroxylated carbon nanotubes
inhibitory mechanism
replica exchange molecular dynamics simulations
TEM experiment
Replica Exchange Molecular Dynamics: A Practical Application Protocol with Solutions to Common Problems and a Peptide Aggregation and Self-Assembly Example.
期刊论文
Methods in molecular biology (Clifton, N.J.), 2018, 卷号: 1777
作者:
Qi Ruxi
;
Wei Guanghong
;
Ma Buyong
;
Nussinov Ruth
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/05
Free energy landscape
GROMACS
Human islet amyloid polypeptide
Molecular dynamics simulations
Protein aggregation
REMD
Replica exchange method
Recent computational studies of membrane interaction and disruption of human islet amyloid polypeptide: Monomers, oligomers and protofibrils
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2018, 卷号: 1860, 期号: 9
作者:
Dong, Xuewei
;
Qiao, Qin
;
Qian, Zhenyu
;
Wei, Guanghong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Human islet amyloid polypeptide
Type 2 diabetes
Amyloid aggregates
Conformational ensemble
Membrane disruption
Molecular dynamics simulations
Recent computational studies of membrane interaction and disruption of human islet amyloid polypeptide: Monomers, oligomers and protofibrils
期刊论文
Biochimica et biophysica acta. Biomembranes, 2018
作者:
Dong Xuewei[1]
;
Qiao Qin[2]
;
Qian Zhenyu[3]
;
Wei Guanghong[4]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/04/24
Amyloid aggregates
Conformational ensemble
Human islet amyloid polypeptide
Membrane disruption
Molecular dynamics simulations
Type 2 diabetes
Intravenous immunoglobulin improves glucose control and beta-cell function in human IAPP transgenic mice by attenuating islet inflammation and reducing IAPP oligomers
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2018, 卷号: 54, 页码: 145-152
作者:
Zhang, Yue
;
Yu, Xiao-lin
;
Zhu, Jie
;
Liu, Shu-ying
;
Liu, Xiang-meng
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2018/06/11
Type 2 Diabetes Mellitus
Intravenous Immunoglobulin
Islet Amyloid Polypeptide
Islet Inflammation
Toxic Oligomer
Inhibitory Mechanism of Epigallocatechin Gallate on Fibrillation and Aggregation of Amidated Human Islet Amyloid Polypeptide
期刊论文
CHEMPHYSCHEM, 2017, 卷号: 18, 期号: 12
作者:
Xu, Zhi-Xue
;
Ma, Gong-Li
;
Zhang, Qiang
;
Chen, Cong-Heng
;
He, Yan-Ming
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
epigallocatechin gallate
human islet amyloid polypeptide
hydrophobic interactions
quantum chemical calculations
pi-pi interactions
Inhibitory Mechanism of Epigallocatechin Gallate on Fibrillation and Aggregation of Amidated Human Islet Amyloid Polypeptide
期刊论文
CHEMPHYSCHEM, 2017, 卷号: 18, 期号: 12
作者:
Xu, Zhi-Xue
;
Ma, Gong-Li
;
Zhang, Qiang
;
Chen, Cong-Heng
;
He, Yan-Ming
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
epigallocatechin gallate
human islet amyloid polypeptide
hydrophobic interactions
quantum chemical calculations
pi-pi interactions
Inhibitory Mechanism of Epigallocatechin Gallate on Fibrillation and Aggregation of Amidated Human Islet Amyloid Polypeptide
期刊论文
Chemphyschem : a European journal of chemical physics and physical chemistry, 2017, 卷号: 18, 页码: 1611-1619
作者:
Xu Zhi-Xue[1]
;
Ma Gong-Li[2]
;
Zhang Qiang[3]
;
Chen Cong-Heng[4]
;
He Yan-Ming[5]
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/04/26
epigallocatechin gallate
human islet amyloid polypeptide
hydrophobic interactions
quantum chemical calculations
π-π interactions
Antioxidation of Cerium Oxide Nanoparticles to Several Series of Oxidative Damage Related to Type II Diabetes Mellitus In Vitro
期刊论文
MEDICAL SCIENCE MONITOR, 2016, 卷号: 22
作者:
Xu, Li
;
Zhai, Jing-hui
;
Wu, Yi
;
Wang, Xiao-ying
;
Cao, Yue
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
Diabetes Mellitus, Type 2
Hydrogen Peroxide
Islet Amyloid Polypeptide
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