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中国医学科学院 北京... [3]
厦门大学 [2]
北京大学 [2]
大连理工大学 [2]
华中师范大学 [2]
长春应用化学研究所 [2]
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期刊论文 [18]
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2019 [1]
2018 [5]
2017 [2]
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2,7-naphthyridinone-based MET kinase inhibitors: A promising novel scaffold for antitumor drug development
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 178, 页码: 705-714
作者:
Zhuo, Lin-Sheng
;
Xu, Hong-Chuang
;
Wang, Ming-Shu
;
Zhao, Xing-E
;
Ming, Zhi-Hui
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/23
2,7-Naphthyridone
Antitumor
In vivo efficacy
MET kinase inhibitor
Near-Infrared Light-Initiated Molecular Superoxide Radical Generator: Rejuvenating Photodynamic Therapy against Hypoxic Tumors
期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018, 卷号: 140, 页码: 14851-14859
作者:
Li, Mingle
;
Xia, Jin
;
Tian, Ruisong
;
Wang, Jingyun
;
Fan, Jiangli
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/02
Cell death
Diseases
Infrared devices
Tumors, Cancer cell apoptosis
Hypoxic environments
Intravenous administration
Near infrared light
Personalized medicines
Photodynamic therapy (PDT)
Radical generation mechanisms
Therapeutic efficacy, Photodynamic therapy, antineoplastic agent
biotin
oxygen
superoxide, antihypoxia activity
apoptosis
Article
cancer cell
cancer inhibition
cancer tissue
cell transport
coculture
disease severity
dose response
drug activity
drug cytotoxicity
drug synthesis
human
in vitro study
in vivo study
ligand binding
neoplasm
nonhuman
patent
personalized medicine
photodynamic therapy
photoreactivity
radiation dose
rejuvenation
tumor ablation
tumor hypoxia
Dotted Core-Shell Nanoparticles for T-1-Weighted MRI of Tumors
期刊论文
ADVANCED MATERIALS, 2018, 卷号: 30, 期号: 33
作者:
Niu, Gang
;
Wu, Aiguo
;
Chen, Xiaoyuan
;
Shen, Zheyu
;
Song, Jibin
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2018/12/04
Energy-loss Spectroscopy
Iron-oxide Nanoparticles
In-vivo
Contrast Agents
Cancer
Cells
T-1
Relaxivity
Diagnosis
Efficacy
Quantitative Evaluation of in Vivo Target Efficacy of Anti-tumor Agents via an Immunofluorescence and EdU Labeling Strategy
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
He, Yujun
;
Wen, Jin
;
Cui, Qinghua
;
Lai, Fangfang
;
Yin, Dali
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/11
anti-tumor drug
in vivo
target efficacy
quantitative analysis
EdU
labeling
immunofluorescence
Quantitative Evaluation of in Vivo Target Efficacy of Anti-tumor Agents via an Immunofluorescence and EdU Labeling Strategy
期刊论文
2018, 卷号: 9, 页码: 812
作者:
He, Yujun
;
Wen, Jin
;
Cui, Qinghua
;
Lai, Fangfang
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/01/03
anti-tumor drug
in vivo
target efficacy
quantitative analysis
EdU labeling
immunofluorescence
IMB-SD62, a triazolothiadiazoles derivative with promising action against tuberculosis
期刊论文
2018, 卷号: 112, 页码: 37-44
作者:
Deng, Qi
;
Meng, Jianzhou
;
Liu, Yishuang
;
Guan, Yan
;
Xiao, Chunling
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
Tuberculosis
Triazolothiadiazoles
In vivo efficacy
Pharmacokinetics
Shikimate dehydrogenase
Effects of linear and branched polyethylene glycol on PEGylation of recombinant hirudin: Reaction kinetics and in vitro and in vivo bioactivities
期刊论文
PROCESS BIOCHEMISTRY, 2017, 卷号: 63, 页码: 154-162
作者:
Wang, Xudong
;
Lv, Li
;
Qin, Kairong
;
Yuan, Hengli
;
Zhang, Fengying
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/03
Recombinant hirudin
PEGylation
Branched mPEG
Reaction kinetics
In vitro anticoagulant activity
In vivo pharmacological efficacy
Trackable Mitochondria-Targeting Nanomicellar Loaded with Doxorubicin for Overcoming Drug Resistance
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2017, 卷号: Vol.9 No.30, 页码: 25152-25163
作者:
Zhang,Ye
;
Zhang,Congjun
;
Li,Jun
;
Hu,Mengyue
;
Bi,Hong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/04/22
VITAMIN-E-TPGS
MULTIDRUG-RESISTANCE
CARBON DOTS
POLYETHYLENE-GLYCOL
CANCER-CELLS
BREAST-CANCER
IN-VIVO
ANTICANCER EFFICACY
CELLULAR UPTAKE
SUCCINATE TPGS
A nanoparticulate drug-delivery system for glaucocalyxin A: formulation, characterization, increased in vitro, and vivo antitumor activity
期刊论文
2016, 卷号: 23, 期号: 7, 页码: 2457-2463
作者:
Han, Meihua
;
Li, Zhitao
;
Guo, Yifei
;
Zhang, Jian
;
Wang, Xiangtao
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/04
Characterization
Glaucocalyxin A nanosuspensions
in vitro antitumor efficacy
in vivo antitumor efficacy
preparation
Design, synthesis and evaluation of novel 5-phenylpyridin-2(1H)-one derivatives as potent reversible Bruton's tyrosine kinase inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: [db:dc_citation_issue], 页码: 348-364
作者:
Zhao, Xinge
;
Xin, Minhang
;
Huang, Wei
;
Ren, Yanliang
;
Jin, Qiu
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/02
Reversible Btk inhibitors
SAR
In vivo
Efficacy
Structure
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