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科研机构
北京大学 [13]
中南大学 [2]
内容类型
期刊论文 [14]
其他 [1]
发表日期
2014 [1]
2013 [1]
2009 [2]
2006 [1]
2005 [1]
2004 [1]
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Huwentoxin-XVI, an analgesic, highly reversible mammalian N-type calcium channel antagonist from Chinese tarantula Ornithoctonus huwena
期刊论文
Neuropharmacology, 2014, 卷号: 79, 页码: 657-667
作者:
Deng, Meichun*
;
Luo, Xuan
;
Xiao, Yucheng
;
Sun, Zhenghua
;
Jiang, Liping
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/03
HWTX-XVI
Tarantula toxin
N-type calcium channels
Dorsal root ganglia
Rat vas deferens
Pain model
Analgesic action
HWTX
Huwentoxin
ICK
inhibitor cystine knot
Cav channel
voltage-gated calcium channel
Nav channel
voltage-gated sodium channel
DRG
dorsal root ganglion
TTX
tetrodotoxin
TTX-R
TTX-resistant
TTX-S
TTX-sensitive
IC50
median inhibitory concentration
Kv channel
voltage-gated potassium channel
HPLC
high pressure liquid chromatography
MALDI-TOF
matrix assisted laser desorption/ionization time-of-flight
Synthesis and biological characterization of synthetic analogs of Huwentoxin-IV (Mu-theraphotoxin-Hh2a), a neuronal tetrodotoxin-sensitive sodium channel inhibitor
期刊论文
Toxicon, 2013, 卷号: 71, 页码: 57-65
作者:
Deng, Meichun*
;
Luo, Xuan
;
Jiang, Liping
;
Chen, Hanchun
;
Wang, Jun
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/03
DRG
Dorsal root ganglion
HPLC
HWTX
HWTX-IV
High pressure liquid chromatography
Huwentoxin
IC(50)
ICK
Inhibitor cystine knot
Kv channel
MALDI-TOF
Matrix assisted laser desorption/ionization time-of-flight
Median inhibitory concentration
Mutant
Patch-clamp
Protein folding
Solid-phase peptide synthesis
TTX
TTX-R
TTX-S
TTX-resistant
TTX-sensitive
Tetrodotoxin
VGSC
Voltage-gated potassium channel
Voltage-gated sodium channel
Soluble expression and one-step purification of a neurotoxin Huwentoxin-I in Escherichia coli
期刊论文
蛋白质表达与纯化, 2009
Che, Nanying
;
Wang, Lili
;
Gao, Yin
;
An, Chengcai
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/11
Huwentoxin-1
Neurotoxin
Soluble expression
Intein
N-VSCC
Whole-cell patch clamp
SPIDER SELENOCOSMIA-HUWENA
CALCIUM-CHANNEL BLOCKER
OMEGA-CONOTOXIN MVIIA
3-DIMENSIONAL STRUCTURE
VENOM
PROTEIN
INTEIN
A lectin from the Chinese bird-hunting spider binds sialic acids
期刊论文
碳水化合物研究, 2009
Siebert, Hans-Christian
;
Lu, Shan-Yun
;
Wechselberger, Rainer
;
Born, Karin
;
Eckert, Thomas
;
Liang, Songping
;
von der Lieth, Claus-Wilhelm
;
Jimenez-Barbero, Jesus
;
Schauer, Roland
;
Vliegenthart, Johannes F. G.
;
Luetteke, Thomas
;
Kozar, Tibor
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2015/11/12
Sialic acid
Lectin
Carbohydrate-protein interaction
Molecular modeling
NMR analysis
PROTEIN-CARBOHYDRATE INTERACTIONS
AB-INITIO CALCULATIONS
SELENOCOSMIA-HUWENA
HEVEIN DOMAINS
HUWENTOXIN-II
3-DIMENSIONAL STRUCTURE
NMR INVESTIGATIONS
SUGAR CODE
DOCKING
VENOM
Nuclear magnetic resonance studies on Huwentoxin-XI from the Chinese bird spider Ornithoctonus huwena: N-15 Labeling and sequence-specific H-1, N-15 nuclear magnetic resonance assignments
期刊论文
acta biochimica et biophysica sinica, 2006
Peng, Kuan
;
Lin, Ying
;
Liang, Song-Ping
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2015/11/14
huwentoxin-XI
toxin
nuclear magnetic resonance
N-15 labeling
sequence-specific assignment
CRYSTAL-STRUCTURES
K+ CHANNELS
TRYPSIN
SITE
Expression and purification of Huwentoxin-I in baculovirus system
期刊论文
蛋白质表达与纯化, 2005
Ji, WJ
;
Zhang, XY
;
Hu, HC
;
Chen, JY
;
Gao, Y
;
Liang, SP
;
An, CC
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/11
Huwentoxin-I
nickel-chelating affinity chromatography
baculovirus expression system
SPIDER SELENOCOSMIA-HUWENA
NEUROTOXIN
SEQUENCE
VENOM
A Kunitz-type Trypsin Inhibitor from the Venom of the Bird SpiderSelenocosmia huwena Wang
其他
2004-01-01
袁春华
;
刁建波
;
林瑛
;
唐建洲
;
聂松
;
谢锦云
;
梁宋平
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/12/03
Huwentoxin-XI
serine proteinase inhibitor
cDNA
expression
RACE
Huwentoxin-XI
serine proteinase inhibitor
cDNA
expression
RACE
Function and solution structure of hainantoxin-1, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana
期刊论文
欧洲生化学会联合会快报, 2003
Li, DL
;
Xiao, YC
;
Hu, WJ
;
Xie, JY
;
Bosmans, F
;
Tytgat, J
;
Liang, SP
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/11
hainantoxin-i
neurotoxin
sodium channel
solution structure
ICK motif
MU-CONOTOXIN GIIIA
3-DIMENSIONAL STRUCTURE
MOLECULAR-MECHANISMS
MEMBRANE-PROTEIN
HUWENTOXIN-I
RAT-BRAIN
TETRODOTOXIN
NEUROTOXINS
EXPRESSION
CURRENTS
cDNA sequence analysis of seven peptide toxins from the spider Selenocosmia huwena
期刊论文
toxicon, 2003
Diao, JB
;
Lin, Y
;
Tang, JZ
;
Liang, SP
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2015/11/12
cDNA sequence
RACE
huwentoxin
inhibitor cystine knot motif
superfamily
Selenocosmia huwena
HUWENTOXIN-I
PHONEUTRIA-NIGRIVENTER
MOLECULAR-CLONING
CYSTINE KNOT
VENOM
CHANNELS
CONOTOXINS
POTENT
MOTIF
Sequence-specific assignment of H-1-NMR resonance and determination of the secondary structure of HWTX-II
期刊论文
acta biochimica et biophysica sinica, 2001
Shu, Q
;
Lu, SY
;
Gu, XC
;
Liang, SP
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/16
HWTX-II
2D-NMR
sequence-specific assignment
secondary structure
SPIDER SELENOCOSMIA-HUWENA
CALCIUM-CHANNEL ANTAGONIST
NUCLEAR-MAGNETIC-RESONANCE
FUNNEL-WEB SPIDER
3-DIMENSIONAL STRUCTURE
CYSTINE KNOT
HUWENTOXIN-I
VENOM
POLYPEPTIDES
NEUROTOXINS
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