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复旦大学上海医学院 [12]
山东大学 [5]
中国医学科学院 北京... [4]
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期刊论文 [34]
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Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 24, 页码: 9370-9387
作者:
Lei, Saifei
;
Clydesdale, Lachlan
;
Dai, Antao
;
Cai, Xiaoqing
;
Feng, Yang
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/01/08
G protein-coupled receptor (GPCR)
glucagon
receptor structure-function
cell signaling
site-directed mutagenesis
biased agonism
GLP-1 receptor
glucagon-like peptide-1
class B peptide hormone
ERK kinase
arrestin
transmembrane domain
Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 24
作者:
Lei, Saifei
;
Clydesdale, Lachlan
;
Dai, Antao
;
Cai, Xiaoqing
;
Feng, Yang
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/05
G protein-coupled receptor (GPCR)
glucagon
receptor structure-function
cell signaling
site-directed mutagenesis
biased agonism
GLP-1 receptor
glucagon-like peptide-1
class B peptide hormone
ERK kinase
arrestin
transmembrane domain
G-protein-coupled receptor kinase-5 promotes glioblastoma progression by targeting the nuclear factor kappa B pathway
期刊论文
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2018, 卷号: 10, 期号: 11, 页码: 3370-3384
作者:
Yang, Yang
;
Wu, Jing-Jing
;
Cheng, Chuan-Dong
;
Bao, De-Jun
;
Dong, Yong-Fei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Glioma
G-protein-coupled receptor kinase-5
nuclear factor kappa B
proliferation
glioma stem cell
blood vessel
High expression of GRK3 is associated with favorable prognosis in pancreatic ductal adenocarcinoma
期刊论文
2018, 卷号: 214, 期号: 2, 页码: 228-232
作者:
Liu, Wen-Jing
;
Zhou, Li
;
Liang, Zhi-Yong
;
Zhou, Wei-Xun
;
You, Lei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
G-protein-coupled receptor kinase 3
Pancreatic ductal adenocarcinoma
Prognosis
Immunohistochemistry
Tissue microarray
Targeting of GIT1 by miR-149*in breast cancer suppresses cell proliferation and metastasis in vitro and tumor growth in vivo
期刊论文
ONCOTARGETS AND THERAPY, 2017, 卷号: 10
作者:
Dong, Yan
;
Chang, Cai
;
Liu, Jingtian
;
Qiang, Jinwei
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
microRNA 149*
miR-149*
G protein-coupled receptor kinase interacting protein 1
GIT1
tumor suppressive role
breast cancer
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:
Yang, Xin
;
Xu, Zhipeng
;
Zhang, Chunlan
;
Cai, Zixin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/12/03
A1c
glycated hemoglobin
AACE
American Association of Clinical Endocrinologists
ACC
acetyl-CoA carboxylase
ADA
American Diabetes Association
Akt/PKB
tyrosine kinase/protein kinase B
AMP
adenosine monophosphate
AMPK
adenosine monophosphate-activated protein
Ang II
angiotensin II
ATP
adenosine triphosphate
BAT
brown adipose tissue
CHOP
CEBP-homologous protein
CEBP
CCAAT enhancer binding protein
CoA
coenzyme A
DPP
Diabetes Prevention Program
EASD
European Association for the Study of Diabetes
eNOS
endothelial nitric oxide synthase
ER
endoplasmic reticulum
FDA
Food and Drug Administration
FFA
free fatty acid
FOXO1
forkhead box protein O1
G6P
glucose 6-phosphate
GDM
gestational diabetes mellitus
GIPR
glucose-dependent insulinotropic polypeptide receptor
GLP-1R
glucagon-like peptide-1 receptor
GLUT1
glucose transporter-1
GLUT4
glucose transporter type 4
GLUTs
glucose transporters
G6P
glucose 6-phosphate, glucose transporter-1
GPR40
G protein-coupled receptor 40
HbA1c
hemoglobin A1c
HGP
hepatic glucose production
HSL
hormone sensitive lipase
IL-6
interleukin 6
INS-1
insulinoma cells in rat
IR
insulin resistance
IRS-1
insulin receptor substrate 1
JNK
c-Jun. N-terminal kinase
Kir6.2
inwardly rectifying potassium/kalium channel
LDs
lipid droplets
LDL
low density lipoprotein
LV
left ventricular
MIN6 cells
mouse insulinoma cells
MAPK
mitogen-activated protein kinases
mPTP
mitochondrial permeability transition pore opening
mTOR
mammalian target of rapamycin
NADPH
nicotinamide adenine dinucleotide phosphate
NF-kappaB
nuclear factors-kappa B
NIT-1 cells
insulinoma cells
p70S6K
p70 ribosomal S6 kinase
PA
palmitic acid
NOS
NADPH oxidase
p38 MAPK
p38 mitogen-activated protein kinase
PA
palmitic acid
PCOS
polycystic ovary syndrome
PGC-1α
peroxisome proliferator-activated receptor-g coactivator-1α
PI3K
phosphatidylinositol 3-kinase
PKB
protein kinase B
PKC
protein kinase C
PPARα
peroxisome-proliferator activated receptor α
PTP
permeability transition pore
RCT
randomized controlled trial
RISK
reperfusion injury salvage kinase
ROS
reactive oxygen species
SERCA2
reticulum sarcoplasmic Ca2 +-ATPase
RISK
reperfusion injury salvage kinase
Smad3
mothers against decapentaplegic homolog 3
SRC-2
steroid receptor coactivator 2
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TGFβ1
transforming growth factor β1
TLR4
Toll-like receptor
TNF-α
tumor necrosis factor α
TR4
testicular receptor 4
UKPDS
United Kingdom Prospective Diabetes Study
VLDL
very low density lipoprotein
Metformin
Pancreatic β Cells
Heart failure
Insulin sensitizer
G protein-coupled estrogen receptor enhances melanogenesis via cAMP-protein kinase (PKA) by upregulating microphthalmia-related transcription factor-tyrosinase in melanoma
期刊论文
The Journal of steroid biochemistry and molecular biology, 2017, 卷号: 165, 期号: Pt B, 页码: 236-246
作者:
Sun, Min
;
Xie, Hong-fu
;
Tang, Yan
;
Lin, Shang-qing
;
Li, Jin-mao
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/03
GPR30
G protein-coupled estrogen receptor
PKA
protein kinase
MITF
microphthalmia-related transcription factor
TYR
tyrosinase
G protein-coupled estrogen receptor (GPER/GPR30)
Melanogenesis
Estrogen
Tyrosinase
Microphthalmia-related transcription factor (MITF)
High expression of G-protein signaling modulator 2 in hepatocellular carcinoma facilitates tumor growth and metastasis by activating the PI3K/AKT signaling pathway
期刊论文
TUMOR BIOLOGY, 2017, 卷号: 39, 期号: 3
作者:
He, Xiao-Qin
;
Zhang, Yue-Feng
;
Yu, Jia-Jun
;
Gan, Yuan-Yuan
;
Han, Na-Na
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
G-protein signaling modulator 2
proliferation
metastasis
G-protein coupled receptor
phosphatidylinositol 3-kinase/protein kinase B
Expression and Significances of G-Protein-Coupled Receptor Kinase 3 in Hepatocellular Carcinoma
期刊论文
2017, 卷号: 8, 期号: 11, 页码: 1972-1978
作者:
Jin Ye
;
Liang Zhi-Yong
;
Zhou Wei-Xun
;
Zhou Li
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/04
hepatocellular carcinoma
G-protein-coupled receptor kinase 3
survival
Effects of paroxetine-mediated inhibition of GRK2 expression on depression and cardiovascular function in patients with myocardial infarction
期刊论文
NEUROPSYCHIATRIC DISEASE AND TREATMENT, 2016, 卷号: 12, 页码: 2333-2341
作者:
Tian, Xiuqing
;
Wang, Qing
;
Guo, Rui
;
Xu, Lingling
;
Chen, Qin M.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/16
selective serotonin reuptake inhibitors
heart rate variability
G
protein-coupled receptor kinase-2
acute myocardial infarction
depression
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