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科研机构
海洋研究所 [3]
北京大学 [2]
大连化学物理研究所 [2]
中南大学 [2]
上海大学 [2]
大连理工大学 [1]
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期刊论文 [15]
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A strategy for comprehensive identification of sequential constituents using ultra-high-performance liquid chromatography coupled with linear ion trap-Orbitrap mass spectrometer, application study on chlorogenic acids in Flos Lonicerae Japonicae
期刊论文
Talanta, 2016, 卷号: 147, 页码: 16-27
作者:
Zhang, Jia-yu
;
Wang, Zi-jian
;
Li, Yun
;
Liu, Ying
;
Cai, Wei
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/03
UPLC–LTQ–Orbitrap
ultra-high-performance liquid chromatography coupled with linear ion trap–Orbitrap
MIM
multiple ion monitoring
MTSF
mass spectral trees similarity filter
HRMS
high resolution mass spectrometer
CGAs
chlorogenic acids
FLJ
Flos Lonicerae Japonicae
DPIs
diagnostic product ions
TCMs
Traditional Chinese medicines
LC–MS
liquid chromatography tandem mass spectrometer
FS–PIL–DE
full scan–parent ions list–dynamic exclusion
ESI
electrospray ionization
PMFs
polymethoxylated flavonoids
CID
collision induced dissociation
SIM
selected ion monitoring
TECD
total extraction component detection
CQA
caffeoylquinic acid
DiCQA
dicaffeoylquinic acid
TriCQA
tricaffeoylquinic acid
pCoQA
p-coumaroylquinic acid
FQA
feruloylquinic acid
SQA
sinapoylquinic acid
pCoCQA
p-coumaroylcaffeoylquinic acid
CFQA
caffeoylferuloylquinic acid
pCoSQA
p-coumaroylsinapoylquinic acid
CSQA
caffeoylsinapoylquinic acid
FSQA
feruloylsinapoylquinic acid.
Chlorogenic acids
Ultra-high-performance liquid chromatography coupled with linear ion trap–Orbitrap
Flos Lonicerae Japonicae
Sequential constituents
Tissue distribution of six major bio-active components after oral administration of Zhenqi Fuzheng capsules to rats using ultra-pressure liquid chromatography-tandem mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2015, 卷号: 986, 页码: 44-53
作者:
Liu, XH
;
Zhu, RJ
;
Hu, F
;
Guo, L
;
Yang, YL
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2016/09/02
UPLC-ESI-MS
CID-MS/MS
MRM
Flavonoids
Saponins
Zhenqi Fuzheng capsule
Tissue distribution
Alternation of adriamycin penetration kinetics in MCF-7 cells from 2D to 3D culture based on P-gp expression through the Chk2/p53/NF-κB pathway
期刊论文
Biochemical Pharmacology, 2015, 卷号: 93, 期号: 2, 页码: 210-220
作者:
Lu, Meng
;
Zhou, Fang
;
Hao, Kun
;
Liu, Jiali
;
Chen, Qianying
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/03
Adriamycin (PubChem CID: 31703)
LY335979 (PubChem CID: 153997)
AZD7762 (PubChem CID: 11152667)
Nutlin-3 (PubChem CID: 216345)
DMSO (PubChem CID: 679)
Propidium iodide (PubChem CID: 104981)
MTT formazan (PubChem CID: 16218671)
ADR
adriamycin
AUC
area under the concentration–time curve
ECM
extracellular matrix
ESI
electrospray ionization
HBSS
Hank's balanced salt solution
LC–MS/MS
liquid chromatography tandem mass spectrometry
MCL
multi-cellular layer
MCR
multi-cellular resistance
MCS
multi-cellular spheroid
MDR
multi-drug resistance
MRM
multiple reaction monitoring
P-gp
P-glycoprotein
PI
propidium iodide
qPCR
quantitative real-time PCR
S.E.
standard error
Multi-cellular layer
Penetration kinetics
P-gp
Chk2/p53/NF-κB pathway
质子化胞嘧啶碰撞诱导解离的实验和理论研究
期刊论文
质谱学报, 2015, 卷号: 36, 页码: 385-393
作者:
陈华鹏[1]
;
张淑琴[2]
;
董俊国[3]
;
翁端[4]
;
程平[5]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/04/30
质子化胞嘧啶
碰撞诱导解离(CID)
电喷雾质谱(ESI-MS)
量化计算
Characterization of laminaran and a highly sulfated polysaccharide from Sargassum fusiforme
期刊论文
CARBOHYDRATE RESEARCH, 2014, 卷号: 385, 页码: 58-64
作者:
Jin, Weihua
;
Zhang, Wenjing
;
Wang, Jing
;
Ren, Sumei
;
Song, Ni
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2015/06/11
ESI-CID-MS/MS
Laminaran
Sargassum fusiforme
NMR
Sulfated polysaccharide
Activity-guided isolation of NF-κB inhibitors and PPARγ agonists from the root bark of Lycium chinense Miller
期刊论文
Journal of Ethnopharmacology, 2014, 卷号: 152, 期号: 3, 页码: 470-477
作者:
Xie, Lian-Wu
;
Atanasov, Atanas G.
;
Guo, De-An
;
Malainer, Clemens
;
Zhang, Jing-Xian
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/28
1D NMR
one-dimensional nuclear magnetic resonance spectroscopy
2D NMR
two-dimensional nuclear magnetic resonance spectroscopy
ANOVA
analysis of variance
AP-1
activator protein 1
CC
column chromatography
CDCl3
deuterated chloroform
C/EBP
CCAAT/enhancer binding protein
CHCl3
chloroform
COSY
correlation spectroscopy in 2D NMR
DCM
dichloromethane
EGFP
enhanced green fluorescent protein
ESI-MS
electrospray ionization mass spectrometry
DMEM
Dulbecco׳s modified Eagle׳s medium
DMSO
dimethyl sulfoxide
EtOAc
ethyl acetate
EtOH
ethanol
FBS
fetal bovine serum
HEK293
human embryonic kidney 293
HMBC
heteronuclear multiple-bond correlation spectroscopy in 2D NMR
HPLC
high performance liquid chromatography
HSQC
heteronuclear single-quantum correlation spectroscopy in 2D NMR
IC50
half maximal inhibitory concentration
IκB
inhibitor of kappa B
IL-6
interleukin 6
IL-1β
interleukin-1 beta
MeOH
methanol
NF-κB
nuclear factor κB
NMR
nuclear magnetic resonance spectroscopy
PE
petroleum ether
PPARγ
peroxisome proliferator-activated receptor γ
TCM
traditional Chinese medicine
TLC
thin layer chromatography
TNF-α
tumor necrosis factor α
Trans-N-(p-coumaroyl)tyramine (PubChem CID: 5372945)
Trans-N-feruloyltyramine (PubChem CID: 5280537)
Trans-N-caffeoyltyramine (PubChem CID: 9994897)
Dihydro-N-caffeoyltyramine (PubChem CID: 16119668)
CHEMBL2337120 (PubChem CID: 71524307)
CHEMBL2337119 (PubChem CID: 71524308)
CHEMBL2337118 (PubChem CID: 71524309)
CHEMBL2337115 (PubChem CID: 71719510)
CHEMBL2337117 (PubChem CID: 71524310)
Lycium chinense Miller
Lycii Radicis Cortex
NF-κB
PPARγ
Phenolic amides
Fatty acids
Activity-guided isolation of NF-κB inhibitors and PPARγ agonists from the root bark of Lycium chinense Miller
期刊论文
Journal of Ethnopharmacology, 2014, 卷号: 152, 期号: 3, 页码: 470-477
作者:
Xie, Lian-Wu
;
Atanasov, Atanas G.
;
Guo, De-An
;
Malainer, Clemens
;
Zhang, Jing-Xian
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/27
1D NMR
one-dimensional nuclear magnetic resonance spectroscopy
2D NMR
two-dimensional nuclear magnetic resonance spectroscopy
ANOVA
analysis of variance
AP-1
activator protein 1
CC
column chromatography
CDCl3
deuterated chloroform
C/EBP
CCAAT/enhancer binding protein
CHCl3
chloroform
COSY
correlation spectroscopy in 2D NMR
DCM
dichloromethane
EGFP
enhanced green fluorescent protein
ESI-MS
electrospray ionization mass spectrometry
DMEM
Dulbecco׳s modified Eagle׳s medium
DMSO
dimethyl sulfoxide
EtOAc
ethyl acetate
EtOH
ethanol
FBS
fetal bovine serum
HEK293
human embryonic kidney 293
HMBC
heteronuclear multiple-bond correlation spectroscopy in 2D NMR
HPLC
high performance liquid chromatography
HSQC
heteronuclear single-quantum correlation spectroscopy in 2D NMR
IC50
half maximal inhibitory concentration
IκB
inhibitor of kappa B
IL-6
interleukin 6
IL-1β
interleukin-1 beta
MeOH
methanol
NF-κB
nuclear factor κB
NMR
nuclear magnetic resonance spectroscopy
PE
petroleum ether
PPARγ
peroxisome proliferator-activated receptor γ
TCM
traditional Chinese medicine
TLC
thin layer chromatography
TNF-α
tumor necrosis factor α
Trans-N-(p-coumaroyl)tyramine (PubChem CID: 5372945)
Trans-N-feruloyltyramine (PubChem CID: 5280537)
Trans-N-caffeoyltyramine (PubChem CID: 9994897)
Dihydro-N-caffeoyltyramine (PubChem CID: 16119668)
CHEMBL2337120 (PubChem CID: 71524307)
CHEMBL2337119 (PubChem CID: 71524308)
CHEMBL2337118 (PubChem CID: 71524309)
CHEMBL2337115 (PubChem CID: 71719510)
CHEMBL2337117 (PubChem CID: 71524310)
Lycium chinense Miller
Lycii Radicis Cortex
NF-κB
PPARγ
Phenolic amides
Fatty acids
Structural analysis of sulfated fucan from Saccharina japonica by electrospray ionization tandem mass spectrometry
期刊论文
CARBOHYDRATE RESEARCH, 2013, 卷号: 369, 页码: 63-67
作者:
Jin, Weihua
;
Guo, Zhimou
;
Wang, Jing
;
Zhang, Wenjing
;
Zhang, Quanbin
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2014/07/17
ESI-CID-MS/MS
Sulfated fucan
Oligosaccharides
Saccharina japonica
Structural analysis of sulfated fucan from Saccharina japonica by electrospray ionization tandem mass spectrometry
期刊论文
carbohydrate research, 2013, 卷号: 369, 页码: 63-67
作者:
Jin, Weihua
;
Guo, Zhimou
;
Wang, Jing
;
Zhang, Wenjing
;
Zhang, Quanbin
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2015/11/09
ESI-CID-MS/MS
Sulfated fucan
Oligosaccharides
Saccharina japonica
Structural analysis of sulfated fucan from Saccharina japonica by electrospray ionization tandem mass spectrometry
期刊论文
carbohydrate research, 2013, 卷号: 369, 页码: 63-67
作者:
Jin, Weihua
;
Guo, Zhimou
;
Wang, Jing
;
Zhang, Wenjing
;
Zhang, Quanbin
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2015/11/09
ESI-CID-MS/MS
Sulfated fucan
Oligosaccharides
Saccharina japonica
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