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Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Picture-word order compound protein interaction: Predicting compound-protein interaction using structural images of compounds
期刊论文
JOURNAL OF COMPUTATIONAL CHEMISTRY, 2021, 页码: 10
作者:
Qian, Ying
;
Li, Xuelian
;
Wu, Jian
;
Zhou, Aimin
;
Xu, Zhijian
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/01/04
compound-protein interaction
convolutional neural network (CNN)
drug-drug interaction
image processing
structural images
Itraconazole and rifampicin, as CYP3A modulators but not P-gp modulators, affect the pharmacokinetics of almonertinib and active metabolite HAS-719 in healthy volunteers
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Liu, Lu
;
Li, Wei
;
Yang, Le
;
Guo, Zi-tao
;
Xue, Hao
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2021/08/17
almonertinib
itraconazole
rifampicin
drug metabolism
drug interaction
CYP3A
P-gp
pharmacokinetics
Effects of rifampicin on the pharmacokinetics of alflutinib, a selective third-generation EGFR kinase inhibitor, and its metabolite AST5902 in healthy volunteers
期刊论文
INVESTIGATIONAL NEW DRUGS, 2021, 页码: 8
作者:
Zhu, Yun-ting
;
Zhang, Yi-fan
;
Jiang, Jin-fang
;
Yang, Yong
;
Guo, Li-xia
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  |  
浏览/下载:31/0
  |  
提交时间:2021/05/24
Alflutinib
Rifampicin
CYP3A4
AST5902
Drug-drug interaction
Therapeutic drugs for SARS-CoV-2 treatment: Current state and perspective
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 90, 页码: 19
作者:
Bolarin, Joshua Adedeji
;
Oluwatoyosi, Mercy Adaramodu
;
Orege, Joshua Iseoluwa
;
Ayeni, Emmanuel Ayodeji
;
Ibrahim, Yusuf Ajibola
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/03/29
COVID-19
Therapeutics
Drug interaction
Antiviral drugs
Health and safety
Pharmacokinetic Drug-drug Interaction of Antibiotics Used in Sepsis Care in China
期刊论文
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 1, 页码: 5-23
作者:
Yu, Xuan
;
Chu, Zixuan
;
Li, Jian
;
He, Rongrong
;
Wang, Yaya
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2021/05/24
Pharmacokinetics
drug-drug interaction
antibiotic
sepsis
transporter
enzyme
In silico drug repositioning using deep learning and comprehensive similarity measures
期刊论文
BMC BIOINFORMATICS, 2021, 卷号: 22, 期号: 增刊3, 页码: 1-14
作者:
Yi, HC (Yi, Hai-Cheng) 1 , 2
;
You, ZH (You, Zhu-Hong) 1
;
Wang, L (Wang, Lei) 1
;
Su, XR (Su, Xiao-Rui) 1 , 2
;
Zhou, X (Zhou, Xi) 1
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/07/14
Drug repositioningDrug-disease interactionGated recurrent unitsGaussian interaction profile kernelMachine learning
Therapeutic drugs for SARS-CoV-2 treatment: Current state and perspective
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 90, 页码: 19
作者:
Bolarin, Joshua Adedeji
;
Oluwatoyosi, Mercy Adaramodu
;
Orege, Joshua Iseoluwa
;
Ayeni, Emmanuel Ayodeji
;
Ibrahim, Yusuf Ajibola
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/25
COVID-19
Therapeutics
Drug interaction
Antiviral drugs
Health and safety
Drug interaction of ningetinib and gefitinib involving CYP1A1 and efflux transporters in non-small cell lung cancer patients
期刊论文
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2020, 页码: 13
作者:
Liu, Lu
;
Wang, Qian
;
Xie, Cen
;
Xi, Ning
;
Guo, Zitao
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/12/24
drug–
drug interaction
gefitinib
ningetinib
transporters
Supramolecular Drug-Drug Complex Vesicles Enable Sequential Drug Release for Enhanced Combination Therapy
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2020, 卷号: 12, 期号: 25, 页码: 27940-27950
作者:
Liu, Chengfei
;
Li, Chunpu
;
Pang, Cui
;
Li, Muqiong
;
Li, Huixin
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/24
drug-drug self-delivery system
supramolecular vesicles
host-guest interaction
self-assembly
pillar[5]arene
combination therapy
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