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Twin drug design, synthesis and evaluation of diosgenin derivatives as multitargeted agents for the treatment of vascular dementia
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 37, 页码: 16
作者:
Yang, Gui-Xiang
;
Sun, Jia-Min
;
Zheng, Lu-Lu
;
Zhang, Li
;
Li, Jie
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/06/11
Vascular dementia
Diosgenin
Antioxidant
Anti-cholinesterase
Multi-target-directed ligands
Prevention properties on cerebral ischemia reperfusion of medicine food homologous Dioscorea yam-derived diosgenin based on mediation of potential targets
期刊论文
FOOD CHEMISTRY, 2021, 卷号: 345
作者:
Zhang, Xinxin
;
Wang, Xingbin
;
Xue, Zhaowei
;
Zhan, Guanqun
;
Ito, Yoichiro
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/11/18
Cerebral ischemia reperfusion
Diosgenin-derived products
Edible Dioscorea yams
Medicine food homologous
Food therapy
Alterations of Brain Quantitative Proteomics Profiling Revealed the Molecular Mechanisms of Diosgenin against Cerebral lschemia Reperfusion Effects
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2020, 卷号: 19, 期号: 3
作者:
Zhang, Xinxin
;
Wang, Xingbin
;
Khurm, Muhammad
;
Zhan, Guanqun
;
Zhang, Hui
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/11/25
diosgenin
cerebral ischemic reperfusion
anti-inflammatory
STAT2
HIKESHI
Synthesis and antitumor activity of novel steroidal imidazolium salt derivatives
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 168, 页码: 232-252
作者:
Deng, Guogang
;
Zhou, Bei
;
Wang, Jing
;
Chen, Zhuo
;
Gong, Liang
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2019/07/29
Diosgenin
Cholesterol
Dehydroepiandrosterone
Imidazolium salt
Antitumor activities
Structure-activity relationships
Diosgenyl Saponin Inducing Endoplasmic Reticulum Stress and Mitochondria-Mediated Apoptotic Pathways in Liver Cancer Cells.
期刊论文
Journal of agricultural and food chemistry, 2019, 卷号: Vol.67 No.41, 页码: 11428-11435
作者:
Xin Meng
;
Honghong Dong
;
Yiwu Pan
;
Long Ma
;
Changxiao Liu
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/11/21
IRE-1α
OATP1B1
apoptosis
diosgenin
endoplasmic reticulum stress
hepatocellular carcinoma
Comparative Transcriptome Analysis Identifies Genes Involved in Diosgenin Biosynthesis in Trigonella foenum-graecum L.
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 14
作者:
Zhang, Yansheng
;
Li, Changfu
;
Zhou, Zilin
;
Li, Xiaohua
;
Zhou, Chen
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  |  
浏览/下载:52/0
  |  
提交时间:2019/03/05
Trigonella foenum-graecum L
diosgenin biosynthesis
glycosyltransferase
cytochrome P450
transcriptional factors
Comparative Transcriptome Analysis Identifies Genes Involved in Diosgenin Biosynthesis in Trigonella foenum-graecum L.
期刊论文
MOLECULES, 2019, 卷号: 24
作者:
Zhou, Chen[1]
;
Li, Xiaohua[2]
;
Zhou, Zilin[3]
;
Li, Changfu[4]
;
Zhang, Yansheng[5]
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  |  
浏览/下载:21/0
  |  
提交时间:2019/04/22
Trigonella foenum-graecum L
diosgenin biosynthesis
glycosyltransferase
cytochrome P450
transcriptional factors
Comparative Transcriptome Analysis Identifies Genes Involved in Diosgenin Biosynthesis in Trigonella foenum-graecum L.
期刊论文
Molecules (Basel, Switzerland), 2019, 卷号: Vol.24 No.1
作者:
Zhou Chen
;
Li Xiaohua
;
Zhou Zilin
;
Li Changfu
;
Zhang Yansheng
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/13
Trigonella
foenum-graecum
L.
cytochrome
P450
diosgenin
biosynthesis
glycosyltransferase
transcriptional
factors
Protective Effects of Diosgenin Against Ultraviolet B (UVB) Radiation-induced Inflammation in Human Dermal Fibroblasts
期刊论文
INTERNATIONAL JOURNAL OF PHARMACOLOGY, 2019, 卷号: 15, 期号: 5, 页码: 623-628
作者:
Li, Song
;
Ma, Dongmei
;
Du, Xiaojing
;
Zhou, Shuhua
;
Song, Yali
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Diosgenin
ultraviolet radiation
anti-photoaging
human dermal
fibroblast
pro-inflammatory cytokines
skin inflammation
Diosgenin regulates cholesterol metabolism in hypercholesterolemic rats by inhibiting NPC1L1 and enhancing ABCG5 and ABCG8
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2019, 卷号: 1864, 期号: 8, 页码: 1124-1133
作者:
Li, Ruoqi
;
Liu, Yi
;
Shi, Jingjing
;
Yu, Yantong
;
Lu, Haifei
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/12/11
Diosgenin
Hypercholesterolemia
NPC1L1
ABCG5/G8
LXR-alpha
Cholesterol metabolism
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